Excimer laser phototherapy for the dissolution of abnormal growth
Abstract
Removal of abnormal human tissue with reduced thermal damage is achieved by selecting a laser having a wavelength in the order of 290 to 400 nm, orienting a laser-transmitting glass member toward the abnormal tissue and directing the laser through the glass member at power densities, pulse rates, and times sufficient to cause multiphoton absorption and bond breaking by Coulomb repulsion rather than thermal destruction. The glass member may include a laser beam concentrator provided by a lens or cone at the tissue-treatment end to increase the beam energy per unit area and reduce the treatment area. 6 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- OSTI Identifier:
- 5273223
- Application Number:
- ON: DE85017803
- Assignee:
- Dept. of Energy
- DOE Contract Number:
- W-31-109-ENG-38
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING; 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; LASERS; THERAPEUTIC USES; NEOPLASMS; SURGERY; FIBER OPTICS; FOCUSING; NEAR ULTRAVIOLET RADIATION; TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTROMAGNETIC RADIATION; MEDICINE; RADIATIONS; ULTRAVIOLET RADIATION; USES; 420300* - Engineering- Lasers- (-1989); 560151 - Radiation Effects on Animals- Man
Citation Formats
Gruen, D M, Young, C E, and Pellin, M J. Excimer laser phototherapy for the dissolution of abnormal growth. United States: N. p., 1985.
Web.
Gruen, D M, Young, C E, & Pellin, M J. Excimer laser phototherapy for the dissolution of abnormal growth. United States.
Gruen, D M, Young, C E, and Pellin, M J. Tue .
"Excimer laser phototherapy for the dissolution of abnormal growth". United States.
@article{osti_5273223,
title = {Excimer laser phototherapy for the dissolution of abnormal growth},
author = {Gruen, D M and Young, C E and Pellin, M J},
abstractNote = {Removal of abnormal human tissue with reduced thermal damage is achieved by selecting a laser having a wavelength in the order of 290 to 400 nm, orienting a laser-transmitting glass member toward the abnormal tissue and directing the laser through the glass member at power densities, pulse rates, and times sufficient to cause multiphoton absorption and bond breaking by Coulomb repulsion rather than thermal destruction. The glass member may include a laser beam concentrator provided by a lens or cone at the tissue-treatment end to increase the beam energy per unit area and reduce the treatment area. 6 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1985},
month = {2}
}
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