Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates
Abstract
The subject invention provides an antibody which specifically binds to the product of a reaction between a labeling substance and a substrate. The subject invention also provides a method of making an immunogen used to produce the antibody of the subject invention. The invention further provides methods of using the subject antibody for detecting an antigen of interest in a sample, for example detecting a protein comprising an amino acid sequence of interest and detecting a nucleic acid molecule comprising a nucleic acid sequence of interest. 8 figs.
- Inventors:
- Issue Date:
- Research Org.:
- University of Vermont
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 516931
- Patent Number(s):
- 5650284
- Application Number:
- PAN: 8-403,649
- Assignee:
- Columbia Univ., New York, NY (United States)
- DOE Contract Number:
- FG02-88ER60742
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 22 Jul 1997
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; IMMUNOASSAY; ANTIBODIES; BIOCHEMICAL REACTION KINETICS; SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; AMINO ACID SEQUENCE; ANTIGENS; NUCLEIC ACIDS
Citation Formats
Erlanger, B F, and Chen, B X. Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates. United States: N. p., 1997.
Web.
Erlanger, B F, & Chen, B X. Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates. United States.
Erlanger, B F, and Chen, B X. Tue .
"Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates". United States.
@article{osti_516931,
title = {Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates},
author = {Erlanger, B F and Chen, B X},
abstractNote = {The subject invention provides an antibody which specifically binds to the product of a reaction between a labeling substance and a substrate. The subject invention also provides a method of making an immunogen used to produce the antibody of the subject invention. The invention further provides methods of using the subject antibody for detecting an antigen of interest in a sample, for example detecting a protein comprising an amino acid sequence of interest and detecting a nucleic acid molecule comprising a nucleic acid sequence of interest. 8 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {7}
}
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