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Title: Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates

Abstract

The subject invention provides an antibody which specifically binds to the product of a reaction between a labeling substance and a substrate. The subject invention also provides a method of making an immunogen used to produce the antibody of the subject invention. The invention further provides methods of using the subject antibody for detecting an antigen of interest in a sample, for example detecting a protein comprising an amino acid sequence of interest and detecting a nucleic acid molecule comprising a nucleic acid sequence of interest. 8 figs.

Inventors:
;
Issue Date:
Research Org.:
University of Vermont
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
516931
Patent Number(s):
5650284
Application Number:
PAN: 8-403,649
Assignee:
Columbia Univ., New York, NY (United States)
DOE Contract Number:  
FG02-88ER60742
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 22 Jul 1997
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; IMMUNOASSAY; ANTIBODIES; BIOCHEMICAL REACTION KINETICS; SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; AMINO ACID SEQUENCE; ANTIGENS; NUCLEIC ACIDS

Citation Formats

Erlanger, B F, and Chen, B X. Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates. United States: N. p., 1997. Web.
Erlanger, B F, & Chen, B X. Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates. United States.
Erlanger, B F, and Chen, B X. Tue . "Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates". United States.
@article{osti_516931,
title = {Enhancing the sensitivity of immunoassay procedures by use of antibodies directed to the product of a reaction between probe labels and assay substrates},
author = {Erlanger, B F and Chen, B X},
abstractNote = {The subject invention provides an antibody which specifically binds to the product of a reaction between a labeling substance and a substrate. The subject invention also provides a method of making an immunogen used to produce the antibody of the subject invention. The invention further provides methods of using the subject antibody for detecting an antigen of interest in a sample, for example detecting a protein comprising an amino acid sequence of interest and detecting a nucleic acid molecule comprising a nucleic acid sequence of interest. 8 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {7}
}