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Title: Method and apparatus for continuously referenced analysis of reactive components in solution

Abstract

A continuously referenced apparatus for measuring the concentration of a reactive chemical species in solution comprises in combination conduit means for introducing a sample solution, means for introducing one or more reactants into a sample solution, and a stream separator disposed within the conduit means for separating the sample solution into a first sample stream and a second sample stream. A reactor is disposed in fluid communication with the first sample stream. A reaction takes place between the reactants introduced and the reactive chemical species of interest, causing the consumption or production of an indicator species in the first sample stream. Measurement means such as a photometric system are disposed in communication with the first and second sample streams, and the outputs of the measurement means are compared to provide a blanked measurement of the concentration of indicator species. The apparatus is particularly suitable for measurement of isoenzymes in body tissues or fluids.

Inventors:
; ;
Issue Date:
OSTI Identifier:
5077176
Assignee:
Dept. of Energy TIC; ERA-05-038413; EDB-80-118002
DOE Contract Number:  
W-7405-ENG-26
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; 47 OTHER INSTRUMENTATION; BODY FLUIDS; QUANTITATIVE CHEMICAL ANALYSIS; MEASURING INSTRUMENTS; TISSUES; DESIGN; ION EXCHANGE CHROMATOGRAPHY; PROTEINS; BIOLOGICAL MATERIALS; BODY; CHEMICAL ANALYSIS; CHROMATOGRAPHY; MATERIALS; ORGANIC COMPOUNDS; SEPARATION PROCESSES; 400104* - Spectral Procedures- (-1987); 550200 - Biochemistry; 440300 - Miscellaneous Instruments- (-1989)

Citation Formats

Bostick, W.D., Denton, M.S., and Dinsmore, S.R. Method and apparatus for continuously referenced analysis of reactive components in solution. United States: N. p., 1979. Web.
Bostick, W.D., Denton, M.S., & Dinsmore, S.R. Method and apparatus for continuously referenced analysis of reactive components in solution. United States.
Bostick, W.D., Denton, M.S., and Dinsmore, S.R. Tue . "Method and apparatus for continuously referenced analysis of reactive components in solution". United States.
@article{osti_5077176,
title = {Method and apparatus for continuously referenced analysis of reactive components in solution},
author = {Bostick, W.D. and Denton, M.S. and Dinsmore, S.R.},
abstractNote = {A continuously referenced apparatus for measuring the concentration of a reactive chemical species in solution comprises in combination conduit means for introducing a sample solution, means for introducing one or more reactants into a sample solution, and a stream separator disposed within the conduit means for separating the sample solution into a first sample stream and a second sample stream. A reactor is disposed in fluid communication with the first sample stream. A reaction takes place between the reactants introduced and the reactive chemical species of interest, causing the consumption or production of an indicator species in the first sample stream. Measurement means such as a photometric system are disposed in communication with the first and second sample streams, and the outputs of the measurement means are compared to provide a blanked measurement of the concentration of indicator species. The apparatus is particularly suitable for measurement of isoenzymes in body tissues or fluids.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1979},
month = {7}
}