Global to push GA events into
skip to main content

Title: Raman-based system for DNA sequencing-mapping and other separations

DNA sequencing and mapping are performed by using a Raman spectrometer with a surface enhanced Raman scattering (SERS) substrate to enhance the Raman signal. A SERS label is attached to a DNA fragment and then analyzed with the Raman spectrometer to identify the DNA fragment according to characteristics of the Raman spectrum generated. 11 figures.
Inventors:
Issue Date:
OSTI Identifier:
5017940
Assignee:
Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States) PTO; EDB-94-077319
Patent Number(s):
US 5306403; A
Application Number:
PPN: US 7-933376
Contract Number:
AC05-84OR21400
Resource Relation:
Patent File Date: 24 Aug 1992
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; DNA SEQUENCERS; DESIGN; DNA SEQUENCING; RAMAN SPECTROSCOPY; GENETIC MAPPING; EQUIPMENT; LABORATORY EQUIPMENT; LASER SPECTROSCOPY; MAPPING; SPECTROSCOPY; STRUCTURAL CHEMICAL ANALYSIS; 550200* - Biochemistry; 550400 - Genetics