Raman-based system for DNA sequencing-mapping and other separations
Abstract
DNA sequencing and mapping are performed by using a Raman spectrometer with a surface enhanced Raman scattering (SERS) substrate to enhance the Raman signal. A SERS label is attached to a DNA fragment and then analyzed with the Raman spectrometer to identify the DNA fragment according to characteristics of the Raman spectrum generated. 11 figures.
- Inventors:
- Issue Date:
- OSTI Identifier:
- 5017940
- Patent Number(s):
- 5306403
- Application Number:
- PPN: US 7-933376
- Assignee:
- Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States)
- DOE Contract Number:
- AC05-84OR21400
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 24 Aug 1992
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; DNA SEQUENCERS; DESIGN; DNA SEQUENCING; RAMAN SPECTROSCOPY; GENETIC MAPPING; EQUIPMENT; LABORATORY EQUIPMENT; LASER SPECTROSCOPY; MAPPING; SPECTROSCOPY; STRUCTURAL CHEMICAL ANALYSIS; 550200* - Biochemistry; 550400 - Genetics
Citation Formats
Vo-Dinh, T. Raman-based system for DNA sequencing-mapping and other separations. United States: N. p., 1994.
Web.
Vo-Dinh, T. Raman-based system for DNA sequencing-mapping and other separations. United States.
Vo-Dinh, T. Tue .
"Raman-based system for DNA sequencing-mapping and other separations". United States.
@article{osti_5017940,
title = {Raman-based system for DNA sequencing-mapping and other separations},
author = {Vo-Dinh, T},
abstractNote = {DNA sequencing and mapping are performed by using a Raman spectrometer with a surface enhanced Raman scattering (SERS) substrate to enhance the Raman signal. A SERS label is attached to a DNA fragment and then analyzed with the Raman spectrometer to identify the DNA fragment according to characteristics of the Raman spectrum generated. 11 figures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {4}
}
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