Tissue irradiator
Abstract
A tissue irradiator is provided for the in-vivo irradiation of body tissue. The irradiator comprises a radiation source material contained and completely encapsulated within vitreous carbon. An embodiment for use as an in- vivo blood irradiator comprises a cylindrical body having an axial bore therethrough. A radioisotope is contained within a first portion of vitreous carbon cylindrically surrounding the axial bore, and a containment portion of vitreous carbon surrounds the radioisotope containing portion, the two portions of vitreous carbon being integrally formed as a single unit. Connecting means are provided at each end of the cylindrical body to permit connections to blood- carrying vessels and to provide for passage of blood through the bore. In a preferred embodiment, the radioisotope is thulium-170 which is present in the irradiator in the form of thulium oxide. A method of producing the preferred blood irradiator is also provided, whereby nonradioactive thulium-169 is dispersed within a polyfurfuryl alcohol resin which is carbonized and fired to form the integral vitreous carbon body and the device is activated by neutron bombardment of the thulium-169 to produce the beta-emitting thulium-170.
- Inventors:
- Issue Date:
- Research Org.:
- Originating Research Org. not identified
- OSTI Identifier:
- 4024280
- Patent Number(s):
- 3927325
- Assignee:
- to U.S. Energy Research and Development Administration
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61N - ELECTROTHERAPY
- NSA Number:
- NSA-33-026116
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 1974 Jul 10; Other Information: A61N5/12; G01N21/24; G21G4/00. Orig. Receipt Date: 30-JUN-76
- Country of Publication:
- United States
- Language:
- English
- Subject:
- N47310* -Isotope & Radiation Source Technology-Radiation Sources-Design & Fabrication; 070201* -Isotope & Radiation Source Technology-Radiation Sources-Design & Fabrication; *RADIATION SOURCE IMPLANTS- DESIGN; BLOOD; IN VIVO; RADIOTHERAPY; THULIUM 170; TISSUES
Citation Formats
Hungate, F P, Riemath, W F, and Bunnell, L R. Tissue irradiator. United States: N. p., 1975.
Web.
Hungate, F P, Riemath, W F, & Bunnell, L R. Tissue irradiator. United States.
Hungate, F P, Riemath, W F, and Bunnell, L R. Tue .
"Tissue irradiator". United States.
@article{osti_4024280,
title = {Tissue irradiator},
author = {Hungate, F P and Riemath, W F and Bunnell, L R},
abstractNote = {A tissue irradiator is provided for the in-vivo irradiation of body tissue. The irradiator comprises a radiation source material contained and completely encapsulated within vitreous carbon. An embodiment for use as an in- vivo blood irradiator comprises a cylindrical body having an axial bore therethrough. A radioisotope is contained within a first portion of vitreous carbon cylindrically surrounding the axial bore, and a containment portion of vitreous carbon surrounds the radioisotope containing portion, the two portions of vitreous carbon being integrally formed as a single unit. Connecting means are provided at each end of the cylindrical body to permit connections to blood- carrying vessels and to provide for passage of blood through the bore. In a preferred embodiment, the radioisotope is thulium-170 which is present in the irradiator in the form of thulium oxide. A method of producing the preferred blood irradiator is also provided, whereby nonradioactive thulium-169 is dispersed within a polyfurfuryl alcohol resin which is carbonized and fired to form the integral vitreous carbon body and the device is activated by neutron bombardment of the thulium-169 to produce the beta-emitting thulium-170.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 16 00:00:00 EST 1975},
month = {Tue Dec 16 00:00:00 EST 1975}
}