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Title: DNA complexes with dyes designed for energy transfer as fluorescent markers

Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated. 4 figures.
Inventors:
;
Issue Date:
OSTI Identifier:
35064
Assignee:
Univ. of California, Oakland, CA (United States) PTO; SCA: 550200; PA: EDB-95:065970; SN: 95001365538
Patent Number(s):
US 5,401,847/A/
Application Number:
PAN: 8-009,704
Contract Number:
FG03-91ER61125
Resource Relation:
Other Information: PBD: 28 Mar 1995
Research Org:
University of California
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; DNA; SEPARATION PROCESSES; DNA SEQUENCING; PHOSPHORS; BIOCHEMICAL REACTION KINETICS; FLUORESCENCE; CHEMICAL SHIFT; BIOLOGICAL MARKERS