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Title: Microinjector for blasocysts

Abstract

An electromechanical device is disclosed for driving the tip of a microinjection cannula, or needle, through the outer barrier of a blastocyst, cell, or cell nucleus for the injection of cells or other bioactive materials. Either a flexible frame or a ram moving within a base member is employed. Cannula motion is achieved by means of a piezoelectric stack and spring return system. The thrust motion over a predetermined microscopic distance is achieved without cannula setback prior to the thrust movement. Instead of specially prepared beveled and tipped needles, standard unimproved cannulas or needles can be used. 6 figs.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Lockheed Martin Energy Research Corporation
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
335469
Patent Number(s):
5,877,008
Application Number:
PAN: 8-898,232
Assignee:
Lockheed Martin Energy Research Corp., Oak Ridge, TN (United States) PTO; SCA: 550300; PA: EDB-99:047345; SN: 99002077364
DOE Contract Number:  
AC05-96OR22464
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 2 Mar 1999
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; DESIGN; LABORATORY EQUIPMENT; SUBCELLULAR DISTRIBUTION; CELL CONSTITUENTS; INJECTION; CELL MEMBRANES

Citation Formats

Remenyik, C.J., Woychik, R.P., Patek, D.R., Hawk, J.A., and Turner, J.C. Microinjector for blasocysts. United States: N. p., 1999. Web.
Remenyik, C.J., Woychik, R.P., Patek, D.R., Hawk, J.A., & Turner, J.C. Microinjector for blasocysts. United States.
Remenyik, C.J., Woychik, R.P., Patek, D.R., Hawk, J.A., and Turner, J.C. Tue . "Microinjector for blasocysts". United States.
@article{osti_335469,
title = {Microinjector for blasocysts},
author = {Remenyik, C.J. and Woychik, R.P. and Patek, D.R. and Hawk, J.A. and Turner, J.C.},
abstractNote = {An electromechanical device is disclosed for driving the tip of a microinjection cannula, or needle, through the outer barrier of a blastocyst, cell, or cell nucleus for the injection of cells or other bioactive materials. Either a flexible frame or a ram moving within a base member is employed. Cannula motion is achieved by means of a piezoelectric stack and spring return system. The thrust motion over a predetermined microscopic distance is achieved without cannula setback prior to the thrust movement. Instead of specially prepared beveled and tipped needles, standard unimproved cannulas or needles can be used. 6 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {3}
}