Plant rhamnogalacturonan II complexation of heavy metal cations
Abstract
The present invention provides rhamnogalacturonan-II (RG-II) and relates to its ability to complex specific multivalent heavy metal cations. In the presence of boric acid, RG-II monomers form dimers that are cross-linked by a borate ester. The yield of such borate ester cross-linked dimers of RG-II is enhanced in the presence of specific heavy metal cations. The present invention further relates to the utility of RG-II in assays for the detection of specific heavy metal contamination; as a reagent useful in the removal of specific heavy metal cations contaminating foods and liquids, for example, fish, wines, etc.; as a pharmaceutical composition useful as an antidote in specific heavy metal cation poisoning; as a treatment for the detoxification of specific heavy metal cations from blood and/or tissues; and in a method of remediation of waters and soils contaminated with specific heavy metal cations. 15 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of Georgia, Athens, GA (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 335468
- Patent Number(s):
- 5877164
- Application Number:
- PAN: 8-755,058
- Assignee:
- Univ. of Georgia Research Foundation, Inc., Athens, GA (United States); Inst. National de la Recherche Agronomique, Paris (France)
- DOE Contract Number:
- FG02-93ER20097; FG05-93ER20115
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 2 Mar 1999
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 54 ENVIRONMENTAL SCIENCES; REMEDIAL ACTION; BIODEGRADATION; PLANTS; METALS; LAND POLLUTION CONTROL; WATER POLLUTION CONTROL
Citation Formats
O`Neill, M A, Pellerin, P J.M., Warrenfeltz, D, Vidal, S, Darvill, A G, and Albersheim, P. Plant rhamnogalacturonan II complexation of heavy metal cations. United States: N. p., 1999.
Web.
O`Neill, M A, Pellerin, P J.M., Warrenfeltz, D, Vidal, S, Darvill, A G, & Albersheim, P. Plant rhamnogalacturonan II complexation of heavy metal cations. United States.
O`Neill, M A, Pellerin, P J.M., Warrenfeltz, D, Vidal, S, Darvill, A G, and Albersheim, P. Tue .
"Plant rhamnogalacturonan II complexation of heavy metal cations". United States.
@article{osti_335468,
title = {Plant rhamnogalacturonan II complexation of heavy metal cations},
author = {O`Neill, M A and Pellerin, P J.M. and Warrenfeltz, D and Vidal, S and Darvill, A G and Albersheim, P},
abstractNote = {The present invention provides rhamnogalacturonan-II (RG-II) and relates to its ability to complex specific multivalent heavy metal cations. In the presence of boric acid, RG-II monomers form dimers that are cross-linked by a borate ester. The yield of such borate ester cross-linked dimers of RG-II is enhanced in the presence of specific heavy metal cations. The present invention further relates to the utility of RG-II in assays for the detection of specific heavy metal contamination; as a reagent useful in the removal of specific heavy metal cations contaminating foods and liquids, for example, fish, wines, etc.; as a pharmaceutical composition useful as an antidote in specific heavy metal cation poisoning; as a treatment for the detoxification of specific heavy metal cations from blood and/or tissues; and in a method of remediation of waters and soils contaminated with specific heavy metal cations. 15 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 02 00:00:00 EST 1999},
month = {Tue Mar 02 00:00:00 EST 1999}
}
Works referenced in this record:
Boron Nutrition of Cultured Tobacco BY-2 Cells. II. Characterization of the Boron-Polysaccharide Complex
journal, January 1997
- Kobayashi, M.; Ohno, K.; Matoh, T.
- Plant and Cell Physiology, Vol. 38, Issue 6
Structural characterization of red wine rhamnogalacturonan II
journal, September 1996
- Pellerin, Patrice; Doco, Thierry; Vida, Stéphane
- Carbohydrate Research, Vol. 290, Issue 2
Two Chains of Rhamnogalacturonan II Are Cross-Linked by Borate-Diol Ester Bonds in Higher Plant Cell Walls
journal, March 1996
- Kobayashi, M.; Matoh, T.; Azuma, Ji.
- Plant Physiology, Vol. 110, Issue 3