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Title: Process for producing 8-fluoropurines

Abstract

An efficient, regio-controlled approach to the synthesis of 8-fluoropurines by direct fluorination of purines with dilute elemental fluorine, or acetyl hypofluorite, is provided. In a preferred embodiment, a purine compound is dissolved in a polar solvent and reacted with a dilute mixture of F{sub 2} in He or other inert gas.

Inventors:
; ; ;
Issue Date:
Research Org.:
University of California
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
321251
Patent Number(s):
5,861,503
Application Number:
PAN: 8-846,424
Assignee:
Univ. of California, Oakland, CA (United States) PTO; SCA: 400201; PA: EDB-99:030944; SN: 99002064425
DOE Contract Number:  
FC03-87ER60615
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 19 Jan 1999
Country of Publication:
United States
Language:
English
Subject:
40 CHEMISTRY; PURINES; FLUORINATION; FLUORINATED AROMATIC HYDROCARBONS; SYNTHESIS

Citation Formats

Barrio, J.R., Satyamurthy, N., Namavari, M., and Phelps, M.E. Process for producing 8-fluoropurines. United States: N. p., 1999. Web.
Barrio, J.R., Satyamurthy, N., Namavari, M., & Phelps, M.E. Process for producing 8-fluoropurines. United States.
Barrio, J.R., Satyamurthy, N., Namavari, M., and Phelps, M.E. Tue . "Process for producing 8-fluoropurines". United States.
@article{osti_321251,
title = {Process for producing 8-fluoropurines},
author = {Barrio, J.R. and Satyamurthy, N. and Namavari, M. and Phelps, M.E.},
abstractNote = {An efficient, regio-controlled approach to the synthesis of 8-fluoropurines by direct fluorination of purines with dilute elemental fluorine, or acetyl hypofluorite, is provided. In a preferred embodiment, a purine compound is dissolved in a polar solvent and reacted with a dilute mixture of F{sub 2} in He or other inert gas.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}