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Title: Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions

Abstract

The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients. 5 figs.

Inventors:
; ; ;
Issue Date:
Research Org.:
Associated Universities Inc
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
321189
Patent Number(s):
5,853,695
Application Number:
PAN: 8-743,287; TRN: 99:003295
Assignee:
Brookhaven Science Associates LLC, Upton, NY (United States) PTO; SCA: 550604; PA: EDB-99:032024; SN: 99002058470
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 29 Dec 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; TIN 117; ISOMERIC NUCLEI; RADIOTHERAPY; SKELETON; PAIN; NEOPLASMS; RADIOPHARMACEUTICALS; THERAPEUTIC USES

Citation Formats

Srivastava, S.C., Meinken, G.E., Mausner, L.F., and Atkins, H.L. Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions. United States: N. p., 1998. Web.
Srivastava, S.C., Meinken, G.E., Mausner, L.F., & Atkins, H.L. Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions. United States.
Srivastava, S.C., Meinken, G.E., Mausner, L.F., and Atkins, H.L. Tue . "Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions". United States.
@article{osti_321189,
title = {Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions},
author = {Srivastava, S.C. and Meinken, G.E. and Mausner, L.F. and Atkins, H.L.},
abstractNote = {The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients. 5 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {12}
}