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Title: Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels

Abstract

Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures. 22 figs.

Inventors:
; ; ;
Issue Date:
Research Org.:
Univ. of California (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
321188
Patent Number(s):
5853992
Application Number:
PAN: 8-726,178
Assignee:
Univ. of California, Oakland, CA (United States)
DOE Contract Number:  
FG03-91ER61125
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 29 Dec 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; CYANINE DYES; MOLECULAR BIOLOGY; DNA SEQUENCING; NUCLEIC ACIDS; MOLECULAR STRUCTURE

Citation Formats

Glazer, A N, Mathies, R A, Hung, S C, and Ju, J. Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels. United States: N. p., 1998. Web.
Glazer, A N, Mathies, R A, Hung, S C, & Ju, J. Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels. United States.
Glazer, A N, Mathies, R A, Hung, S C, and Ju, J. Tue . "Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels". United States.
@article{osti_321188,
title = {Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels},
author = {Glazer, A N and Mathies, R A and Hung, S C and Ju, J},
abstractNote = {Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures. 22 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {12}
}