Capillary zone electrophoresis-mass spectrometer interface

D`Silva, A

Title: Capillary zone electrophoresis-mass spectrometer interface

Full Record
Other Related Research

Abstract

A device for providing equal electrical potential between two loci unconnected by solid or liquid electrical conductors is provided. The device comprises a first electrical conducting terminal, a second electrical conducting terminal connected to the first terminal by a rigid dielectric structure, and an electrically conducting gas contacting the first and second terminals. This device is particularly suitable for application in the electrospray ionization interface between a capillary zone electrophoresis apparatus and a mass spectrometer. 1 fig.

Inventors:: D`Silva, A

Issue Date:: 1996-08-06

Research Org.:: Iowa State Univ., Ames, IA (United States)

OSTI Identifier:: 288022

Patent Number(s):: 5543618

Application Number:: PAN: 8-268,501

Assignee:: Iowa State Univ. Research Foundation, Inc., Ames, IA (United States)

DOE Contract Number:: W-7405-ENG-82

Resource Type:: Patent

Resource Relation:: Other Information: PBD: 6 Aug 1996

Country of Publication:: United States

Language:: English

Subject:: 40 CHEMISTRY; ELECTROPHORESIS; SEPARATION EQUIPMENT; EQUIPMENT INTERFACES; MASS SPECTROMETERS; DESIGN; ELECTRICAL EQUIPMENT; OPERATION

Citation Formats


                    D`Silva, A. Capillary zone electrophoresis-mass spectrometer interface.  United States: N. p., 1996. 
        Web.

Copy to clipboard


                    D`Silva, A. Capillary zone electrophoresis-mass spectrometer interface.  United States.

Copy to clipboard


                    D`Silva, A. Tue .  
        "Capillary zone electrophoresis-mass spectrometer interface".  United States.

Copy to clipboard


                    
@article{osti_288022,

  title        = {Capillary zone electrophoresis-mass spectrometer interface},

  author       = {D`Silva, A},

  abstractNote = {A device for providing equal electrical potential between two loci unconnected by solid or liquid electrical conductors is provided. The device comprises a first electrical conducting terminal, a second electrical conducting terminal connected to the first terminal by a rigid dielectric structure, and an electrically conducting gas contacting the first and second terminals. This device is particularly suitable for application in the electrospray ionization interface between a capillary zone electrophoresis apparatus and a mass spectrometer. 1 fig.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1996},

  month        = {8}

}

Copy to clipboard

Patent:

Search for the full text at the U.S. Patent and Trademark Office

Save / Share:

Export Metadata

Save to My Library

Similar Records in DOE Patents and OSTI.GOV collections:

Capillary zone electrophoresis-mass spectrometer interface

Patent D'Silva, Arthur [Ames, IA]

A device for providing equal electrical potential between two loci unconnected by solid or liquid electrical conducts is provided. The device comprises a first electrical conducting terminal, a second electrical conducting terminal connected to the first terminal by a rigid dielectric structure, and an electrically conducting gas contacting the first and second terminals. This device is particularly suitable for application in the electrospray ionization interface between a capillary zone electrophoresis apparatus and a mass spectrometer.
Full Text Available
Capillary electrophoresis electrospray ionization mass spectrometry interface

Patent Smith, R D; Severs, J C

The present invention is an interface between a capillary electrophoresis separation capillary end and an electrospray ionization mass spectrometry emitter capillary end, for transporting an analyte sample from a capillary electrophoresis separation capillary to a electrospray ionization mass spectrometry emitter capillary. The interface of the present invention has: (a) a charge transfer fitting enclosing both of the capillary electrophoresis capillary end and the electrospray ionization mass spectrometry emitter capillary end; (b) a reservoir containing an electrolyte surrounding the charge transfer fitting; and (c) an electrode immersed into the electrolyte, the electrode closing a capillary electrophoresis circuit and providing charge transfermore » « less
Capillary electrophoresis electrospray ionization mass spectrometry interface

Patent Smith, Richard D [Richland, WA]; Severs, Joanne C [Hayward, CA]

The present invention is an interface between a capillary electrophoresis separation capillary end and an electrospray ionization mass spectrometry emitter capillary end, for transporting an anolyte sample from a capillary electrophoresis separation capillary to a electrospray ionization mass spectrometry emitter capillary. The interface of the present invention has: (a) a charge transfer fitting enclosing both of the capillary electrophoresis capillary end and the electrospray ionization mass spectrometry emitter capillary end; (b) a reservoir containing an electrolyte surrounding the charge transfer fitting; and (c) an electrode immersed into the electrolyte, the electrode closing a capillary electrophoresis circuit and providing charge transfermore » « less
Full Text Available
Sheathless interface for coupling capillary electrophoresis with mass spectrometry

Patent Wang, Chenchen; Tang, Keqi; Smith, Richard D.

A sheathless interface for coupling capillary electrophoresis (CE) with mass spectrometry is disclosed. The sheathless interface includes a separation capillary for performing CE separation and an emitter capillary for electrospray ionization. A portion of the emitter capillary is porous or, alternatively, is coated to form an electrically conductive surface. A section of the emitter capillary is disposed within the separation capillary, forming a joint. A metal tube, containing a conductive liquid, encloses the joint.
Full Text Available
Improved electrospray ionization interface for capillary zone electrophoresis-mass spectrometry

Journal Article Smith, R D; Barinaga, C J; Udseth, H R - Anal. Chem.; (United States)

A new electrospray ionization interface for capillary zone electrophoresis-mass spectrometry (CZE-MS) is described. The interface uses a sheath flow of liquid to make the electrical contact at the CZE terminus, thus defining both the CZE and electrospray field gradients. This allows the composition of the electrosprayed liquid to be controlled independently of the CZE buffer, providing operation with buffers that could not be used previously (e.g., aqueous and high ionic strength buffers). The interface operation is independent of CZE flow rate; CZE capillaries are easily replaced and require no additional preparation. Since the electrospray occurs directly from the CZE capillarymore » « less
DOI: https://doi.org/10.1021/ac00169a022

Similar Records