Gene for ataxia-telangiectasia complementation group D (ATDC)
Abstract
Disclosed herein is a new gene, an AT gene for complementation group D, the ATDC gene and fragments thereof. Nucleic acid probes for the gene are provided as well as proteins encoded by the gene, cDNA therefrom, preferably a 3 kilobase (kb) cDNA, and recombinant nucleic acid molecules for expression of the proteins. Further disclosed are methods to detect mutations in the gene, preferably methods employing the polymerase chain reaction (PCR). Also disclosed are methods to detect AT genes from other AT complementation groups. 30 figs.
- Inventors:
- Issue Date:
- Research Org.:
- University of California
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 27712
- Patent Number(s):
- 5,395,767
- Application Number:
- PAN: 7-903,466
- Assignee:
- Univ. of California, Oakland, CA (United States)
- DOE Contract Number:
- W-7405-ENG-48; AC03-76SF01012
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 7 Mar 1995
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; NERVOUS SYSTEM DISEASES; GENES; VASCULAR DISEASES; GENE MUTATIONS; MEASURING METHODS; GENE REGULATION; DNA-CLONING
Citation Formats
Murnane, J P, Painter, R B, Kapp, L N, and Yu, L C. Gene for ataxia-telangiectasia complementation group D (ATDC). United States: N. p., 1995.
Web.
Murnane, J P, Painter, R B, Kapp, L N, & Yu, L C. Gene for ataxia-telangiectasia complementation group D (ATDC). United States.
Murnane, J P, Painter, R B, Kapp, L N, and Yu, L C. Tue .
"Gene for ataxia-telangiectasia complementation group D (ATDC)". United States.
@article{osti_27712,
title = {Gene for ataxia-telangiectasia complementation group D (ATDC)},
author = {Murnane, J P and Painter, R B and Kapp, L N and Yu, L C},
abstractNote = {Disclosed herein is a new gene, an AT gene for complementation group D, the ATDC gene and fragments thereof. Nucleic acid probes for the gene are provided as well as proteins encoded by the gene, cDNA therefrom, preferably a 3 kilobase (kb) cDNA, and recombinant nucleic acid molecules for expression of the proteins. Further disclosed are methods to detect mutations in the gene, preferably methods employing the polymerase chain reaction (PCR). Also disclosed are methods to detect AT genes from other AT complementation groups. 30 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {3}
}
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