Gene for ataxia-telangiectasia complementation group D (ATDC)

Murnane, J P; Painter, R B; Kapp, L N; Yu, L C

Title: Gene for ataxia-telangiectasia complementation group D (ATDC)

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Abstract

Disclosed herein is a new gene, an AT gene for complementation group D, the ATDC gene and fragments thereof. Nucleic acid probes for the gene are provided as well as proteins encoded by the gene, cDNA therefrom, preferably a 3 kilobase (kb) cDNA, and recombinant nucleic acid molecules for expression of the proteins. Further disclosed are methods to detect mutations in the gene, preferably methods employing the polymerase chain reaction (PCR). Also disclosed are methods to detect AT genes from other AT complementation groups. 30 figs.

Inventors:: Murnane, J P; Painter, R B; Kapp, L N; Yu, L C

Issue Date:: 1995-03-07

Research Org.:: Univ. of California (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 27712

Patent Number(s):: 5395767

Application Number:: PAN: 7-903,466

Assignee:: Univ. of California, Oakland, CA (United States)

DOE Contract Number:: W-7405-ENG-48; AC03-76SF01012

Resource Type:: Patent

Resource Relation:: Other Information: PBD: 7 Mar 1995

Country of Publication:: United States

Language:: English

Subject:: 55 BIOLOGY AND MEDICINE, BASIC STUDIES; NERVOUS SYSTEM DISEASES; GENES; VASCULAR DISEASES; GENE MUTATIONS; MEASURING METHODS; GENE REGULATION; DNA-CLONING

Citation Formats


                    Murnane, J P, Painter, R B, Kapp, L N, and Yu, L C. Gene for ataxia-telangiectasia complementation group D (ATDC).  United States: N. p., 1995. 
        Web.

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                    Murnane, J P, Painter, R B, Kapp, L N, & Yu, L C. Gene for ataxia-telangiectasia complementation group D (ATDC).  United States.

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                    Murnane, J P, Painter, R B, Kapp, L N, and Yu, L C. Tue .  
        "Gene for ataxia-telangiectasia complementation group D (ATDC)".  United States.

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@article{osti_27712,

  title        = {Gene for ataxia-telangiectasia complementation group D (ATDC)},

  author       = {Murnane, J P and Painter, R B and Kapp, L N and Yu, L C},

  abstractNote = {Disclosed herein is a new gene, an AT gene for complementation group D, the ATDC gene and fragments thereof. Nucleic acid probes for the gene are provided as well as proteins encoded by the gene, cDNA therefrom, preferably a 3 kilobase (kb) cDNA, and recombinant nucleic acid molecules for expression of the proteins. Further disclosed are methods to detect mutations in the gene, preferably methods employing the polymerase chain reaction (PCR). Also disclosed are methods to detect AT genes from other AT complementation groups. 30 figs.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1995},

  month        = {3}

}

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