Methods of transfection using sonoporation
Abstract
The present invention relates to methods of transforming a cell by use of an acoustic transducer. In particular embodiments, the radiofrequency signal to the transducer can be tuned to provide optimal membrane disruption of the cell; and an agent, such as a nucleic acid, can then be delivered to the cell.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE National Nuclear Security Administration (NNSA)
- OSTI Identifier:
- 2293952
- Patent Number(s):
- 11834650
- Application Number:
- 16/446,971
- Assignee:
- National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
- DOE Contract Number:
- NA0003525
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 06/20/2019
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Ruffing, Anne, Branch, Darren W., and Manginell, Ronald P. Methods of transfection using sonoporation. United States: N. p., 2023.
Web.
Ruffing, Anne, Branch, Darren W., & Manginell, Ronald P. Methods of transfection using sonoporation. United States.
Ruffing, Anne, Branch, Darren W., and Manginell, Ronald P. Tue .
"Methods of transfection using sonoporation". United States. https://www.osti.gov/servlets/purl/2293952.
@article{osti_2293952,
title = {Methods of transfection using sonoporation},
author = {Ruffing, Anne and Branch, Darren W. and Manginell, Ronald P.},
abstractNote = {The present invention relates to methods of transforming a cell by use of an acoustic transducer. In particular embodiments, the radiofrequency signal to the transducer can be tuned to provide optimal membrane disruption of the cell; and an agent, such as a nucleic acid, can then be delivered to the cell.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2023},
month = {12}
}
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