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Title: Methods of transfection using sonoporation

Abstract

The present invention relates to methods of transforming a cell by use of an acoustic transducer. In particular embodiments, the radiofrequency signal to the transducer can be tuned to provide optimal membrane disruption of the cell; and an agent, such as a nucleic acid, can then be delivered to the cell.

Inventors:
; ;
Issue Date:
Research Org.:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
2293952
Patent Number(s):
11834650
Application Number:
16/446,971
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
DOE Contract Number:  
NA0003525
Resource Type:
Patent
Resource Relation:
Patent File Date: 06/20/2019
Country of Publication:
United States
Language:
English

Citation Formats

Ruffing, Anne, Branch, Darren W., and Manginell, Ronald P. Methods of transfection using sonoporation. United States: N. p., 2023. Web.
Ruffing, Anne, Branch, Darren W., & Manginell, Ronald P. Methods of transfection using sonoporation. United States.
Ruffing, Anne, Branch, Darren W., and Manginell, Ronald P. Tue . "Methods of transfection using sonoporation". United States. https://www.osti.gov/servlets/purl/2293952.
@article{osti_2293952,
title = {Methods of transfection using sonoporation},
author = {Ruffing, Anne and Branch, Darren W. and Manginell, Ronald P.},
abstractNote = {The present invention relates to methods of transforming a cell by use of an acoustic transducer. In particular embodiments, the radiofrequency signal to the transducer can be tuned to provide optimal membrane disruption of the cell; and an agent, such as a nucleic acid, can then be delivered to the cell.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2023},
month = {12}
}

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