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Title: P-coumaroyl-CoA:monolignol transferases

Abstract

The invention is directed to p-coumaroyl-CoA:monolignol transferase enzymes, nucleic acids encoding p-coumaroyl-CoA:monolignol transferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of p-coumaroyl-CoA:monolignol transferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Univ. of Wisconsin, Madison, WI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
2293822
Patent Number(s):
11807876
Application Number:
17/107,108
Assignee:
Wisconsin Alumni Research Foundation (Madison, WI)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
FC02-07ER64494
Resource Type:
Patent
Resource Relation:
Patent File Date: 11/30/2020
Country of Publication:
United States
Language:
English

Citation Formats

Ralph, John, Karlen, Steven D., Smith, Rebecca Anne, Fox, Brian, Beebe, Emily, and Bingman, Craig. P-coumaroyl-CoA:monolignol transferases. United States: N. p., 2023. Web.
Ralph, John, Karlen, Steven D., Smith, Rebecca Anne, Fox, Brian, Beebe, Emily, & Bingman, Craig. P-coumaroyl-CoA:monolignol transferases. United States.
Ralph, John, Karlen, Steven D., Smith, Rebecca Anne, Fox, Brian, Beebe, Emily, and Bingman, Craig. Tue . "P-coumaroyl-CoA:monolignol transferases". United States. https://www.osti.gov/servlets/purl/2293822.
@article{osti_2293822,
title = {P-coumaroyl-CoA:monolignol transferases},
author = {Ralph, John and Karlen, Steven D. and Smith, Rebecca Anne and Fox, Brian and Beebe, Emily and Bingman, Craig},
abstractNote = {The invention is directed to p-coumaroyl-CoA:monolignol transferase enzymes, nucleic acids encoding p-coumaroyl-CoA:monolignol transferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of p-coumaroyl-CoA:monolignol transferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 07 00:00:00 EST 2023},
month = {Tue Nov 07 00:00:00 EST 2023}
}

Works referenced in this record:

Strcuture and transcription of the nopaline synthase gene region of T-DNA
journal, January 1983


Lignin Biosynthesis
journal, June 2003


Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
journal, February 1998


Anti-gene therapy: the use of ribozymes to inhibit gene function
journal, December 1996


Plants having enhanced yield-related traits and a method for making the same
patent, August 2016


Engineering monolignol p-coumarate conjugates into Poplar and Arabidopsis lignins
journal, October 2015


Assaying chimeric genes in plants: The GUS gene fusion system
journal, December 1987


Cloning and expression of the cDNA coding for aequorin, a bioluminescent calcium-binding protein
journal, February 1985


Next-generation ammonia pretreatment enhances cellulosic biofuel production
journal, January 2016


Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
patent, January 1995


Progressive sequence alignment as a prerequisitetto correct phylogenetic trees
journal, August 1987


Structure and expression of the maize gene encoding the phosphoenolpyruvate carboxylase isozyme involved in C4 photosynthesis
journal, May 1989


RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
journal, December 1998


A single amino acid converts a repressor to an activator of flowering
journal, May 2005


The challenges of genome sequence annotation or “The devil is in the details”
journal, November 1997


Defining the Diverse Cell Populations Contributing to Lignification in Arabidopsis Stems
journal, April 2017


Method for preparing fertile transgenic corn plants
patent, July 1996


Direct gene transfer to cells of a graminaceous monocot
journal, May 1985


Antioxidant Properties of Hydroxycinnamic Acids: A Review of Structure- Activity Relationships
journal, November 2013


Insights into corn genes derived from large-scale cDNA sequencing
journal, October 2008


Genetic Requirements for Inheritance of RNAi in C. elegans
journal, March 2000


Naturally p-Hydroxybenzoylated Lignins in Palms
journal, February 2015


Maize sucrose synthase-1 promoter directs phloem cell-specific expression of Gus gene in transgenic tobacco plants
journal, June 1990


Green fluorescent protein: an in vivo reporter of plant gene expression
journal, April 1995


Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions
patent-application, September 2011


Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega
journal, January 2011


Invasive cleavage of nucleic acids
patent, November 1999


Solution-state 2D NMR of Ball-milled Plant Cell Wall Gels in DMSO-d 6
journal, March 2008


Herbicide Resistance in Transgenic Plants Expressing a Bacterial Detoxification Gene
journal, October 1988


Reverse genetics by fast neutron mutagenesis in higher plants
journal, November 2002


Paving the Way for Lignin Valorisation: Recent Advances in Bioengineering, Biorefining and Catalysis
journal, June 2016


The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
journal, October 1999


Synthesis of feruloylated and p-coumaroylated methyl glycosides
journal, May 1992


Method for preparing fertile transgenic corn plants
patent, July 1996


Muting circuit for AM stereophonic receiver
patent, December 1984


Facile Synthesis of 4-Hydroxycinnamyl p-Coumarates
journal, August 1998


Enzymatic Synthesis and Purification of Aromatic Coenzyme A Esters
journal, March 2002


Isolation of an efficient actin promoter for use in rice transformation.
journal, February 1990


Basic local alignment search tool
journal, October 1990


Identification of DNA sequences required for activity of the cauliflower mosaic virus 35S promoter
journal, February 1985


CLUSTAL: a package for performing multiple sequence alignment on a microcomputer
journal, December 1988


Lignans from the wood of Aralia bipinnata
journal, July 1995


Whole plant cell wall characterization using solution-state 2D NMR
journal, August 2012


Comparison of biosequences
journal, December 1981


Quorum sensing inhibition activity of garlic extract andp-coumaric acid
journal, November 2009


Effects of γ-valerolactone in hydrolysis of lignocellulosic biomass to monosaccharides
journal, January 2014


mut-7 of C. elegans, Required for Transposon Silencing and RNA Interference, Is a Homolog of Werner Syndrome Helicase and RNaseD
journal, October 1999


Cell-Free Protein Synthesis for Functional and Structural Studies
book, October 2013


Feruloyl-CoA; Monolignol Transferase
patent-application, August 2017


Detection of nucleic acid sequences by invader-directed cleavage
patent, December 1999


Method and apparatus for audio bass enhancement
patent-application, July 2006


Transformation of Maize Cells and Regeneration of Fertile Transgenic Plants.
journal, July 1990


RNA Interference
journal, March 2000


Solution-state 2D NMR of ball-milled plant cell wall gels in DMSO-d6/pyridine-d5
journal, January 2010


Isolation and characterization of a maize chlorophyll a/b binding protein gene that produces high levels of mRNA in the dark
journal, February 1989


Multiple sequence alignment with hierarchical clustering
journal, November 1988


Statistics of local complexity in amino acid sequences and sequence databases
journal, June 1993


Parallelization of a local similarity algorithm
journal, April 1992


Time-Course Accumulation of Main Bioactive Components in the Rhizome of Ligusticum chuanxiong
journal, December 2006


Detection and Determination of p-Coumaroylated Units in Lignins
journal, May 1999


Chromogenic identification of genetic regulatory signals in Bacillus subtilis based on expression of a cloned Pseudomonas gene.
journal, February 1983


p-Coumaroyl-CoA:Monolignol Transferase
patent-application, February 2016


Stable Transformation of Soybean (Glycine Max) by Particle Acceleration
journal, August 1988


Characterization of nonderivatized plant cell walls using high-resolution solution-state NMR spectroscopy
journal, June 2008


RNAi and double-strand RNA
journal, January 1999


Ester Groups in Lignin
journal, August 1955


Role of PHABULOSA and PHAVOLUTA in determining radial patterning in shoots
journal, June 2001


The α-Amylase Gene as a Marker for Gene Cloning: Direct Screening of Recombinant Clones
journal, March 1990


Pathway of p-Coumaric Acid Incorporation into Maize Lignin As Revealed by NMR
journal, October 1994


Cell ablation using trans-splicing ribozymes
patent, June 1997


A High-Throughput Platform for Screening Milligram Quantities of Plant Biomass for Lignocellulose Digestibility
journal, January 2010


Conversion of p-coumarate into caffeate by Streptomyces nigrifaciens. Purification and properties of the hydroxylating enzyme
journal, November 1972


Transient Expression of Chimeric Genes Delivered into Pollen by Microprojectile Bombardment
journal, December 1989


Stable transformation of soybean by electroporation and root formation from transformed callus
journal, June 1987


Amino acid substitution matrices from protein blocks.
journal, November 1992


Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions
patent-application, October 2013


Methods for Pretreatment of Lignocellulosic Biomass for Efficient Hydrolysis and Biofuel Production
journal, April 2009

  • Kumar, Parveen; Barrett, Diane M.; Delwiche, Michael J.
  • Industrial & Engineering Chemistry Research, Vol. 48, Issue 8, p. 3713-3729
  • https://doi.org/10.1021/ie801542g

Hybridization of nucleic acids immobilized on solid supports
journal, May 1984


Policing rogue genes
journal, November 1999


Lignin monomer production integrated into the γ-valerolactone sugar platform
journal, January 2015


Lignin monomer composition is determined by the expression of a cytochrome P450-dependent monooxygenase in Arabidopsis
journal, June 1998


Phenolic constituents from the core of Kenaf (Hibiscus cannabinus)
journal, April 2001


Lignins: Natural polymers from oxidative coupling of 4-hydroxyphenyl- propanoids
journal, January 2004


Transient and Stable Expression of the Firefly Luciferase Gene in Plant Cells and Transgenic Plants
journal, November 1986


Reductive Cleavage Method for Quantitation of Monolignols and Low-Abundance Monolignol Conjugates
journal, May 2018


Expression of a soybean ?-conclycinin gene under the control of the Cauliflower Mosaic Virus 35S and 19S promoters in transformed petunia tissues
journal, January 1987


BdCESA7, BdCESA8, and BdPMT Utility Promoter Constructs for Targeted Expression to Secondary Cell-Wall-Forming Cells of Grasses
journal, February 2016


Method for modifying lignin structure using monolignol ferulate conjugates
patent, October 2013


Production of Transgenic Soybean Plants Using Agrobacterium-Mediated DNA Transfer
journal, August 1988


DNA sequences required for anaerobic expression of the maize alcohol dehydrogenase 1 gene
journal, October 1987


Highly Decorated Lignins in Leaf Tissues of the Canary Island Date Palm Phoenix canariensis
journal, September 2017


Nonenzymatic Sugar Production from Biomass Using Biomass-Derived  -Valerolactone
journal, January 2014


A new, structurally nonredundant, diverse data set of protein-protein interfaces and its implications
journal, April 2004


Transient Gene Expression in Intact and Organized Rice Tissues.
journal, July 1990


Hibiscus cannabinus feruloyl-coa:monolignol transferase
patent, November 2016


p -Coumaroyl-CoA:monolignol transferase (PMT) acts specifically in the lignin biosynthetic pathway in Brachypodium distachyon
journal, February 2014


Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
journal, May 2001


Over-Expression of Tobacco knotted 1-Type Class1 Homeobox Genes Alters Various Leaf Morphology
journal, May 2000


Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
patent-application, December 2007


Expression of a Maize Cell Wall Hydroxyproline-Rich Glycoprotein Gene in Early Leaf and Root Vascular Differentiation
journal, August 1990


Modulation of Expression of Acyltransferases to Modify Hydroxycinnamic Acid Content
patent-application, October 2015


Solvent-Enabled Nonenyzmatic Sugar Production from Biomass for Chemical and Biological Upgrading
journal, March 2015


Site-directed mutagenesis of mouse dihydrofolate reductase. Mutants with increased resistance to methotrexate and trimethoprim.
journal, September 1988


Protein annotation: detective work for function prediction
journal, June 1998


Gene transfer to cereals: an assessment
journal, October 1989


Stable transformation of maize cells by electroporation
patent, December 1995


Information enhancement methods for large scale sequence analysis
journal, June 1993


Identification of an essential upstream element in the nopaline synthase promoter by stable and transient assays
journal, August 1987


Bacterial antimutagenesis by hydroxycinnamic acids from plant cell walls
journal, December 2003


Improved tools for biological sequence comparison.
journal, April 1988


Self-Splicing of Group i Introns
journal, June 1990


Antioxidant and antigenotoxic effects of plant cell wall hydroxycinnamic acids in cultured HT‐29 cells
journal, May 2005


Method of inducing lysine overproduction in plants
patent, November 1993


Developmentally regulated expression of the bean  -phaseolin gene in tobacco seed
journal, May 1985


Lignin engineering
journal, June 2008


Go hunting in sequence databases but watch out for the traps
journal, October 1996


Monolignol Ferulate Transferase Introduces Chemically Labile Linkages into the Lignin Backbone
journal, April 2014


Monolignol ferulate conjugates are naturally incorporated into plant lignins
journal, October 2016


Two Regulatory Genes of the Maize Anthocyanin Pathway Are Homologous: Isolation of B Utilizing R Genomic Sequences
journal, December 1989


Simple RNA enzymes with new and highly specific endoribonuclease activities
journal, August 1988


BLAST+: architecture and applications
journal, January 2009


The Effects on Lignin Structure of Overexpression of Ferulate 5-Hydroxylase in Hybrid Poplar 1
journal, April 2009


Additivity of mutational effects in proteins
journal, September 1990


Syringyl Methacrylate, a Hardwood Lignin-Based Monomer for High- T g Polymeric Materials
journal, April 2016


A general method applicable to the search for similarities in the amino acid sequence of two proteins
journal, March 1970


Construction of an efficient expression vector for coupled transcription/translation in a wheat germ cell-free system
journal, October 2000


Expression of the REB transcriptional activator in rice grains improves the yield of recombinant proteins whose genes are controlled by a Reb -responsive promoter
journal, September 2001


Conversion of hydroxycinnamic acids into volatile phenols in a synthetic medium and in red wine by Dekkera bruxellensis
journal, March 2012


Strategies for the Conversion of Lignin to High-Value Polymeric Materials: Review and Perspective
journal, December 2015


Hibiscus Cannabinus Feruloyl-Coa:Monolignol Transferase
patent-application, January 2015


A Single Mutation Converts a Novel Phosphotyrosine Binding Domain into a Dual-specificity Phosphatase
journal, November 1995


Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast
journal, November 2016


Fast and sensitive multiple sequence alignments on a microcomputer
journal, April 1989


Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions
patent-application, August 2007


Cloning and Expression of the Tyrosinase Gene from Streptomyces antibioticus in Streptomyces lividans
journal, September 1983


Formaldehyde stabilization facilitates lignin monomer production during biomass depolymerization
journal, October 2016


p-Hydroxybenzoate groups in the lignin of aspen (populus tremula)
journal, January 1955


Thermotropic Liquid‐Crystalline Polymer Derived from Natural Cinnamoyl Biomonomers
journal, March 2004


Lignin Biosynthesis and Structure
journal, May 2010


Vascular expression of a bean cell wall glycine-rich protein-β-glucuronidase gene fusion in transgenic tobacco
journal, May 1989


Targeted screening for induced mutations
journal, April 2000


The bialaphos biosynthetic genes ofStreptomyces hygroscopicus: Molecular cloning and characterization of the gene cluster
journal, October 1986


Identification of Grass-specific Enzyme That Acylates Monolignols with p-Coumarate
journal, January 2012


Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana
journal, December 1998


Application of CRISPR/Cas9 in plant biology
journal, May 2017


Structural Redesigning Arabidopsis Lignins into Alkali-Soluble Lignins through the Expression of p- Coumaroyl-CoA:Monolignol Transferase PMT
journal, January 2016


GATEWAY™ vectors for Agrobacterium-mediated plant transformation
journal, May 2002


Impact of lignin polymer backbone esters on ionic liquid pretreatment of poplar
journal, April 2017


Lignans from Ochroma lagopus Swartz
journal, November 1995


Cinnamate-4-Hydroxylase Expression in Arabidopsis (Regulation in Response to Development and the Environment)
journal, March 1997


Ribozyme engineering
journal, August 1992


A Polyethylene Glycol-Mediated Protoplast Transformation System for Production of Fertile Transgenic Rice Plants
journal, July 1990


Identification and suppression of the p‐ coumaroyl CoA:hydroxycinnamyl alcohol transferase in Zea mays L.
journal, May 2014


Metabolic engineering of novel lignin in biomass crops
journal, October 2012


Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.
journal, August 1978


The Chemistry of Self-Splicing RNA and RNA Enzymes
journal, June 1987


Protein tolerance to random amino acid change
journal, June 2004


Feruloyl-CoA:monolignol transferase
patent, September 2016


Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi
journal, September 2002


Feruloyl-CoA:monolignol transferase
patent, November 2016