Device and method to manipulate ions in multi-level system

Ibrahim, Yehia M.; Hollerbach, Adam L.; Li, Ailin

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Title: Device and method to manipulate ions in multi-level system

Abstract

An apparatus includes multiple levels of ion transport channels, with successive levels coupled by elevator channels. Efficient three dimensional packing provides long path lengths in practical volumes for ion mobility separation with high resolving power. Disclosed elevator configurations provide efficient routing of ion transport channels across levels with low ion loss, enabling ion mobility separation over 100 levels or more. Elevator configurations include (i) opposed traveling waves meeting at an elevator entrance, (ii) external elevator with a wrap-around electrode bank, (iii) external elevator with electrode banks on parallel extension plates, or (iv) elevator operating in surfing mode, in various combinations. Manufacture is aided by printed wiring boards, with interchangeable boards. Assembly with motherboard, spacer block(s), and alignment pins provides efficient distribution of electrode excitations and accurate reproducible positioning.

Inventors:: Ibrahim, Yehia M.; Hollerbach, Adam L.; Li, Ailin

Issue Date:: Tue Oct 24 00:00:00 EDT 2023

Research Org.:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Org.:: USDOE; National Institutes of Health (NIH)

OSTI Identifier:: 2293759

Patent Number(s):: 11796504

Application Number:: 17/399,629

Assignee:: Battelle Memorial Institute (Richland, WA)

DOE Contract Number:: AC05-76RL01830; CA217699; GM103493-10; GM130709-01

Resource Type:: Patent

Resource Relation:: Patent File Date: 08/11/2021

Country of Publication:: United States

Language:: English

Citation Formats


                    Ibrahim, Yehia M., Hollerbach, Adam L., and Li, Ailin. Device and method to manipulate ions in multi-level system.  United States: N. p., 2023. 
        Web.

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                    Ibrahim, Yehia M., Hollerbach, Adam L., & Li, Ailin. Device and method to manipulate ions in multi-level system.  United States.

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                    Ibrahim, Yehia M., Hollerbach, Adam L., and Li, Ailin. Tue .  
        "Device and method to manipulate ions in multi-level system".  United States.  https://www.osti.gov/servlets/purl/2293759.

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@article{osti_2293759,

  title        = {Device and method to manipulate ions in multi-level system},

  author       = {Ibrahim, Yehia M. and Hollerbach, Adam L. and Li, Ailin},

  abstractNote = {An apparatus includes multiple levels of ion transport channels, with successive levels coupled by elevator channels. Efficient three dimensional packing provides long path lengths in practical volumes for ion mobility separation with high resolving power. Disclosed elevator configurations provide efficient routing of ion transport channels across levels with low ion loss, enabling ion mobility separation over 100 levels or more. Elevator configurations include (i) opposed traveling waves meeting at an elevator entrance, (ii) external elevator with a wrap-around electrode bank, (iii) external elevator with electrode banks on parallel extension plates, or (iv) elevator operating in surfing mode, in various combinations. Manufacture is aided by printed wiring boards, with interchangeable boards. Assembly with motherboard, spacer block(s), and alignment pins provides efficient distribution of electrode excitations and accurate reproducible positioning.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Oct 24 00:00:00 EDT 2023},

  month        = {Tue Oct 24 00:00:00 EDT 2023}

}

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Title: Device and method to manipulate ions in multi-level system

Abstract

Citation Formats

System and method for collisional activation of charged particles patent, September 2013

Ion funnel ion trap and process patent, February 2011

Method and apparatus for ion mobility separations utilizing alternating current waveforms patent, June 2019

Method and apparatus for spatial compression and increased mobility resolution of ions patent, July 2018

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Ion Elevators and Escalators in Multilevel Structures for Lossless Ion Manipulations journal, January 2017

Characterization of Traveling Wave Ion Mobility Separations in Structures for Lossless Ion Manipulations journal, October 2015

Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS) with Improved Ion Transmission and IMS Resolution patent-application, December 2014

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Method and device for ion mobility separations patent, July 2017

Method and device for ion mobility separation patent, September 2019

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Ion manipulation device with electrical breakdown protection patent, December 2014

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Serpentine Ultralong Path with Extended Routing (SUPER) High Resolution Traveling Wave Ion Mobility-MS using Structures for Lossless Ion Manipulations journal, April 2017

Hooked differential mobility spectrometry apparatus and method therefore patent, February 2009

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Method and Apparatus for Ion Mobility Separations Utilizing Alternating Current Waveforms patent-application, January 2019

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Method and apparatus for ion mobility separations utilizing alternating current waveforms
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Device for separating non-ions from ions
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Apparatus and method of dissociating ions in a multipole ion guide
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Squeezing of Ion Populations and Peaks in Traveling Wave Ion Mobility Separations and Structures for Lossless Ion Manipulations Using Compression Ratio Ion Mobility Programming
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Device to manipulate ions of same or different polarities
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Method and apparatus for compressing ions
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