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Title: Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions

Compounds and methods for single step, covalent labeling of the phosphate group of an organic substance under aqueous conditions are described. The labeling compound includes any kind of detectable signal group covalently bound to an imidazole moiety, which can be imidazole or a substituted imidazole. A preferred labeling compound has the formula shown in the accompanying diagram. 4 figs.
Inventors:
;
Issue Date:
OSTI Identifier:
224972
Assignee:
Northeastern Univ., Boston, MA (United States) PTO; SCA: 400202; PA: INS-96:011389; EDB-96:080666; SN: 96001577509
Patent Number(s):
US 5,512,486/A/
Application Number:
PAN: 8-060,569
Contract Number:
FG02-90ER60964
Resource Relation:
Other Information: PBD: 30 Apr 1996
Research Org:
Northeastern University
Country of Publication:
United States
Language:
English
Subject:
40 CHEMISTRY; PHOSPHATES; LABELLING; DNA ADDUCTS; AQUEOUS SOLUTIONS; IMIDAZOLES; MOLECULAR STRUCTURE

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