System and method for three-dimensional in vitro flexible microelectrode array
Abstract
The present disclosure relates to a biocompatible, in vitro probe system. The probe system may have a substrate and a culture well supported on the substrate. The culture well defines a three-dimensional volume for containing in vitro cultures of electroactive cells. The probe system has at least one probe subsystem supported on the substrate. The probe subsystem has at least one probe having an array of electrodes, with the probe being disposed within the culture well for in vitro electrically communicating with the electroactive cells. The probe subsystem is adapted to be interfaced to an external instrumentation/recording device.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 2222168
- Patent Number(s):
- 11725170
- Application Number:
- 16/677,328
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- DOE Contract Number:
- AC52-07NA27344
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 11/07/2019
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Soscia, David, Enright, Heather Ann, Fischer, Nicholas, Lam, Doris Mailie, Tooker, Angela C., Triplett, Michael, and Wheeler, Elizabeth K. System and method for three-dimensional in vitro flexible microelectrode array. United States: N. p., 2023.
Web.
Soscia, David, Enright, Heather Ann, Fischer, Nicholas, Lam, Doris Mailie, Tooker, Angela C., Triplett, Michael, & Wheeler, Elizabeth K. System and method for three-dimensional in vitro flexible microelectrode array. United States.
Soscia, David, Enright, Heather Ann, Fischer, Nicholas, Lam, Doris Mailie, Tooker, Angela C., Triplett, Michael, and Wheeler, Elizabeth K. Tue .
"System and method for three-dimensional in vitro flexible microelectrode array". United States. https://www.osti.gov/servlets/purl/2222168.
@article{osti_2222168,
title = {System and method for three-dimensional in vitro flexible microelectrode array},
author = {Soscia, David and Enright, Heather Ann and Fischer, Nicholas and Lam, Doris Mailie and Tooker, Angela C. and Triplett, Michael and Wheeler, Elizabeth K.},
abstractNote = {The present disclosure relates to a biocompatible, in vitro probe system. The probe system may have a substrate and a culture well supported on the substrate. The culture well defines a three-dimensional volume for containing in vitro cultures of electroactive cells. The probe system has at least one probe subsystem supported on the substrate. The probe subsystem has at least one probe having an array of electrodes, with the probe being disposed within the culture well for in vitro electrically communicating with the electroactive cells. The probe subsystem is adapted to be interfaced to an external instrumentation/recording device.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2023},
month = {8}
}
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