Multiplexed fluorescence detector system for capillary electrophoresis
Abstract
A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis. 14 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Iowa State Univ., Ames, IA (United States)
- OSTI Identifier:
- 203884
- Patent Number(s):
- 5498324
- Application Number:
- PAN: 8-223,864
- Assignee:
- Iowa State Univ. Research Foundation, Inc., Ames, IA (United States)
- DOE Contract Number:
- W-7405-ENG-82
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 12 Mar 1996
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; ELECTROPHORESIS; OPTIMIZATION; MONITORS; DESIGN; LASER RADIATION; FIBER OPTICS; SEPARATION PROCESSES; MICROSCOPY
Citation Formats
Yeung, E S, and Taylor, J A. Multiplexed fluorescence detector system for capillary electrophoresis. United States: N. p., 1996.
Web.
Yeung, E S, & Taylor, J A. Multiplexed fluorescence detector system for capillary electrophoresis. United States.
Yeung, E S, and Taylor, J A. Tue .
"Multiplexed fluorescence detector system for capillary electrophoresis". United States.
@article{osti_203884,
title = {Multiplexed fluorescence detector system for capillary electrophoresis},
author = {Yeung, E S and Taylor, J A},
abstractNote = {A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis. 14 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1996},
month = {3}
}
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