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Title: Biomarkers of cell senescence

The present invention provides a biomarker system for the in vivo and in vitro assessment of cell senescence. In the method of the present invention, {beta}-galactosidase activity is utilized as a means by which cell senescence may be assessed either in in vitro cell cultures or in vivo. 1 fig.
Inventors:
; ;
Issue Date:
OSTI Identifier:
201520
Assignee:
Univ. of California, Oakland, CA (United States) PTO; SCA: 550200; PA: EDB-96:056060; SN: 96001551788
Patent Number(s):
US 5,491,069/A/
Application Number:
PAN: 8-198,436
Contract Number:
AC03-76SF00098
Resource Relation:
Other Information: PBD: 13 Feb 1996
Research Org:
University of California
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; BIOLOGICAL MARKERS; DESIGN; GALACTOSIDASE; ENZYME ACTIVITY; ANIMAL CELLS; LIFE CYCLE

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