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Title: Automated two-dimensional interface for capillary gas chromatography

A multidimensional gas chromatograph (GC) system is disclosed which has wide bore capillary and narrow bore capillary GC columns in series and has a novel system interface. Heart cuts from a high flow rate sample, separated by a wide bore GC column, are collected and directed to a narrow bore GC column with carrier gas injected at a lower flow compatible with a mass spectrometer. A bimodal six-way valve is connected with the wide bore GC column outlet and a bimodal four-way valve is connected with the narrow bore GC column inlet. A trapping and retaining circuit with a cold trap is connected with the six-way valve and a transfer circuit interconnects the two valves. The six-way valve is manipulated between first and second mode positions to collect analyte, and the four-way valve is manipulated between third and fourth mode positions to allow carrier gas to sweep analyte from a deactivated cold trap, through the transfer circuit, and then to the narrow bore GC capillary column for separation and subsequent analysis by a mass spectrometer. Rotary valves have substantially the same bore width as their associated columns to minimize flow irregularities and resulting sample peak deterioration. The rotary valves aremore » heated separately from the GC columns to avoid temperature lag and resulting sample deterioration. 3 figs.« less
Inventors:
;
Issue Date:
OSTI Identifier:
201518
Assignee:
Lovelace Biomedical and Environmental Research Inst., Inc., Albuquerque, NM (United States) PTO; SCA: 400102; 400105; PA: EDB-96:054429; SN: 96001551780
Patent Number(s):
US 5,492,555/A/
Application Number:
PAN: 8-257,388
Contract Number:
AC04-76EV01013
Resource Relation:
Other Information: PBD: 20 Feb 1996
Research Org:
Lovelace Biomedical and Environmental Research Institute
Country of Publication:
United States
Language:
English
Subject:
40 CHEMISTRY; EXTRACTION COLUMNS; EQUIPMENT INTERFACES; MASS SPECTROMETERS; DESIGN; GAS CHROMATOGRAPHY; GAS ANALYSIS; MASS SPECTROSCOPY; SEPARATION PROCESSES; SAMPLE PREPARATION; CAPILLARY FLOW