Dendritic gold nanoparticles and methods of synthesis
Abstract
A method of producing dendritic gold nanoparticles by combining a gold precursor solution, a reducing agent, and a bifunctional peptide having an amine-rich amino acid sequence into a buffered aqueous solution in a single container, and agitating the mixture causing the formation of the dendritic gold nanoparticles having a surface with a positive charge and a second end portion of the bifunctional peptide exposed on the surface of the dendritic gold nanoparticles. The dendritic gold nanoparticles may be used to deliver therapeutic, diagnostic, and/or immunogenic amino acid sequences as portions of the bifunctional peptide.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of Oklahoma, Norman, OK (United States)
- Sponsoring Org.:
- USDOE; National Institutes of Health (NIH)
- OSTI Identifier:
- 1998319
- Patent Number(s):
- 11634507
- Application Number:
- 16/838,798
- Assignee:
- The Board of Regents of the University of Oklahoma (Norman, OK)
- DOE Contract Number:
- SC0016567; EB021339
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 04/02/2020
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Mao, Chuanbin, Wang, Lin, and Qiu, Penghe. Dendritic gold nanoparticles and methods of synthesis. United States: N. p., 2023.
Web.
Mao, Chuanbin, Wang, Lin, & Qiu, Penghe. Dendritic gold nanoparticles and methods of synthesis. United States.
Mao, Chuanbin, Wang, Lin, and Qiu, Penghe. Tue .
"Dendritic gold nanoparticles and methods of synthesis". United States. https://www.osti.gov/servlets/purl/1998319.
@article{osti_1998319,
title = {Dendritic gold nanoparticles and methods of synthesis},
author = {Mao, Chuanbin and Wang, Lin and Qiu, Penghe},
abstractNote = {A method of producing dendritic gold nanoparticles by combining a gold precursor solution, a reducing agent, and a bifunctional peptide having an amine-rich amino acid sequence into a buffered aqueous solution in a single container, and agitating the mixture causing the formation of the dendritic gold nanoparticles having a surface with a positive charge and a second end portion of the bifunctional peptide exposed on the surface of the dendritic gold nanoparticles. The dendritic gold nanoparticles may be used to deliver therapeutic, diagnostic, and/or immunogenic amino acid sequences as portions of the bifunctional peptide.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2023},
month = {4}
}
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Works referenced in this record:
Synthesis of Highly Branched Gold Nanodendrites with a Narrow Size Distribution and Tunable NIR and SERS Using a Multiamine Surfactant
journal, July 2013
- Jia, Wenfeng; Li, Jinru; Jiang, Long
- ACS Applied Materials & Interfaces, Vol. 5, Issue 15
A gold nanoflower-based traceable drug delivery system for intracellular SERS imaging-guided targeted chemo-phototherapy
journal, January 2018
- Song, Chunyuan; Dou, Yanxia; Yuwen, Lihui
- Journal of Materials Chemistry B, Vol. 6, Issue 19
Multibranched Gold Nanoparticles with Intrinsic LAT-1 Targeting Capabilities for Selective Photothermal Therapy of Breast Cancer
journal, November 2017
- Ong, Zhan Yuin; Chen, Shu; Nabavi, Elham
- ACS Applied Materials & Interfaces, Vol. 9, Issue 45
Tuning photothermal properties of gold nanodendrites for in vivo cancer therapy within a wide near infrared range by simply controlling their degree of branching
journal, October 2016
- Qiu, Penghe; Yang, Mingying; Qu, Xuewei
- Biomaterials, Vol. 104