Composition for detecting alpha particle radiation and methods of use
Abstract
A capsule composition comprising: (a) a polyester shell having a thickness of no more than 20 microns, and (b) a solution containing a visual and/or olfactory indicator, wherein the solution is encapsulated by the polyester shell. Also described herein is a method for detecting alpha particle radiation, in which: (i) the capsule composition is placed in contact with an esterase in a location where the presence of alpha particle radiation is being determined; (ii) waiting a period of time for the esterase to degrade the polyester shells, wherein the period of time is insufficient for the esterase to cause leakage of the solution in the absence of alpha particle radiation but is sufficient for alpha particle radiation, if present, to cause leakage from the capsule composition; and (iii) observing whether leakage has occurred at the end of the period of time to determine whether alpha particle radiation is present.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1987140
- Patent Number(s):
- 11584919
- Application Number:
- 16/748,039
- Assignee:
- UT-Battelle LLC (Oak Ridge, TN)
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 01/21/2020
- Country of Publication:
- United States
- Language:
- English
Citation Formats
McKnight, Timothy E., Graham, David E., Standaert, Robert F., Lewis, Linda A., and Lewis, Samuel A. Composition for detecting alpha particle radiation and methods of use. United States: N. p., 2023.
Web.
McKnight, Timothy E., Graham, David E., Standaert, Robert F., Lewis, Linda A., & Lewis, Samuel A. Composition for detecting alpha particle radiation and methods of use. United States.
McKnight, Timothy E., Graham, David E., Standaert, Robert F., Lewis, Linda A., and Lewis, Samuel A. Tue .
"Composition for detecting alpha particle radiation and methods of use". United States. https://www.osti.gov/servlets/purl/1987140.
@article{osti_1987140,
title = {Composition for detecting alpha particle radiation and methods of use},
author = {McKnight, Timothy E. and Graham, David E. and Standaert, Robert F. and Lewis, Linda A. and Lewis, Samuel A.},
abstractNote = {A capsule composition comprising: (a) a polyester shell having a thickness of no more than 20 microns, and (b) a solution containing a visual and/or olfactory indicator, wherein the solution is encapsulated by the polyester shell. Also described herein is a method for detecting alpha particle radiation, in which: (i) the capsule composition is placed in contact with an esterase in a location where the presence of alpha particle radiation is being determined; (ii) waiting a period of time for the esterase to degrade the polyester shells, wherein the period of time is insufficient for the esterase to cause leakage of the solution in the absence of alpha particle radiation but is sufficient for alpha particle radiation, if present, to cause leakage from the capsule composition; and (iii) observing whether leakage has occurred at the end of the period of time to determine whether alpha particle radiation is present.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2023},
month = {2}
}
Works referenced in this record:
Dry Products Comprising a Sheet and Two Phases
patent-application, March 2005
- Hauser, Matthias; Martens, Nicolas; Ansmann, Achim
- US Patent Application 10/483616; 20050048856
Products Comprising an Applicator and Lipid and Aqueous Phase
patent-application, July 2006
- Hauser, Matthias; Ansmann, Achim; Issberner, Ulrich
- US Patent Application 10/521070; 20060154834
PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
journal, December 2013
- McCall, Rebecca L.; Sirianni, Rachael W.
- Journal of Visualized Experiments, Issue 82
Dry Products Comprising an Applicator and Two Phases
patent-application, July 2006
- Hauser, Matthias; Issberner, Ulrich; Annsmann, Achim
- US Patent Application 10/520952; 20060159924
A review on fluorescent inorganic nanoparticles for optical sensing applications
journal, January 2016
- Ng, Sing Muk; Koneswaran, Masilamany; Narayanaswamy, Ramaier
- RSC Advances, Vol. 6, Issue 26
Products Comprising a Sheet and a Lipid and Aqueous Phase
patent-application, February 2005
- Martens, Nicholas; Ansmann, Achim; Hauser, Matthias
- US Patent Application 10/483633; 20050031847
Measurement of radon and xenon binding to a cryptophane molecular host
journal, June 2011
- Jacobson, D. R.; Khan, N. S.; Colle, R.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 27, p. 10969-10973
Dry Products Comprising an Applicator and a Wax Phase
patent-application, October 2006
- Hauser, Matthias; Ansmann, Achim; Issberner, Ulrich
- US Patent Application 10/520970; 20060222686
Rodent-repellent microcapsules and preparations thereof
patent, March 1991
- Kondo, Takeshi; Ueda, Osamu; Fukakusa, Yoshiya
- US Patent Document 5,002,768
A novel application for 222Rn emanation standards: Radon–cryptophane host chemistry
journal, September 2012
- Laureano-Perez, L.; Collé, R.; Jacobson, D. R.
- Applied Radiation and Isotopes, Vol. 70, Issue 9
Comparative study on the enzymatic degradation of poly(lactic-co-glycolic acid) by hydrolytic enzymes based on the colorimetric quantification of glycolic acid
journal, October 2011
- Kemme, Michael; Prokesch, Ines; Heinzel-Wieland, Regina
- Polymer Testing, Vol. 30, Issue 7
Liposome Coated with Polyhydroxyalkanoate and Production Method Thereof
patent-application, June 2003
- Nomoto, Tsuyoshi; Yano, Tetsuya; Kozaki, Shinya
- US Patent Application 10/190490; 20030113368
Products Comprising an Applicator and a Wax Dispersion
patent-application, October 2006
- Hauser, Matthias; Sans, Anne
- US Patent Application 10/541950; 20060233866
Composition for Detecting Alpha Particle Radiation and Methods of Use
patent-application, July 2020
- McKnight, Timothy E.; Graham, David E.; Standaert, Robert F.
- US Patent Application 16/748039; 20200231951