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Title: Systems for producing radionuclides using minimal target material

Abstract

Among the various aspects of the present disclosure is the provision of systems for producing radioisotopes and improving the specific activity of radioisotopes (e.g., Cu-64 chloride). As described herein, the system includes a target material area or target material shape that matches the proton beam strike area or proton beam strike shape, resulting in optimal thickness with less target material required.

Inventors:
Issue Date:
Research Org.:
Washington Univ., St. Louis, MO (United States)
Sponsoring Org.:
USDOE; National Institutes of Health (NIH)
OSTI Identifier:
1986797
Patent Number(s):
11495365
Application Number:
16/352,516
Assignee:
Washington University (St. Louis, MO)
DOE Contract Number:  
FG02-87EF60512; CA086307
Resource Type:
Patent
Resource Relation:
Patent File Date: 03/13/2019
Country of Publication:
United States
Language:
English

Citation Formats

Gaehle, Gregory. Systems for producing radionuclides using minimal target material. United States: N. p., 2022. Web.
Gaehle, Gregory. Systems for producing radionuclides using minimal target material. United States.
Gaehle, Gregory. Tue . "Systems for producing radionuclides using minimal target material". United States. https://www.osti.gov/servlets/purl/1986797.
@article{osti_1986797,
title = {Systems for producing radionuclides using minimal target material},
author = {Gaehle, Gregory},
abstractNote = {Among the various aspects of the present disclosure is the provision of systems for producing radioisotopes and improving the specific activity of radioisotopes (e.g., Cu-64 chloride). As described herein, the system includes a target material area or target material shape that matches the proton beam strike area or proton beam strike shape, resulting in optimal thickness with less target material required.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2022},
month = {11}
}

Works referenced in this record:

High purity production and potential applications of copper-60 and copper-61
journal, May 1999


Production of .sup.64 Cu and other radionuclides using a charged-particle accelerator
patent, January 2000


Simultaneous production of high specific activity 64Cu and 61Co with 11.4MeV protons on enriched 64Ni nuclei
journal, October 2007


Module-assisted preparation of 64Cu with high specific activity
journal, April 2012


Alternative method for 64Cu radioisotope production
journal, July 2009


Efficient preparation of high-quality 64Cu for routine use
journal, November 2016


Automation of 64Cu production at Turku PET Centre
journal, July 2014


Automated Separation, Purification and Labeling System for 60CU, 61CU and 64CU Radionuclides and Recovery Thereof
patent-application, January 2006


Radiosynthesis and quality control of [ 11 C]TASP457 as a clinically useful PET ligand for imaging of histamine H 3 receptors in human brain
journal, November 2016


A semi-automated system for the routine production of copper-64
journal, August 2012


A simple and efficient method of nickel electrodeposition for the cyclotron production of 64Cu
journal, July 2014