Systems for producing radionuclides using minimal target material
Abstract
Among the various aspects of the present disclosure is the provision of systems for producing radioisotopes and improving the specific activity of radioisotopes (e.g., Cu-64 chloride). As described herein, the system includes a target material area or target material shape that matches the proton beam strike area or proton beam strike shape, resulting in optimal thickness with less target material required.
- Inventors:
- Issue Date:
- Research Org.:
- Washington Univ., St. Louis, MO (United States)
- Sponsoring Org.:
- USDOE; National Institutes of Health (NIH)
- OSTI Identifier:
- 1986797
- Patent Number(s):
- 11495365
- Application Number:
- 16/352,516
- Assignee:
- Washington University (St. Louis, MO)
- DOE Contract Number:
- FG02-87EF60512; CA086307
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 03/13/2019
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Gaehle, Gregory. Systems for producing radionuclides using minimal target material. United States: N. p., 2022.
Web.
Gaehle, Gregory. Systems for producing radionuclides using minimal target material. United States.
Gaehle, Gregory. Tue .
"Systems for producing radionuclides using minimal target material". United States. https://www.osti.gov/servlets/purl/1986797.
@article{osti_1986797,
title = {Systems for producing radionuclides using minimal target material},
author = {Gaehle, Gregory},
abstractNote = {Among the various aspects of the present disclosure is the provision of systems for producing radioisotopes and improving the specific activity of radioisotopes (e.g., Cu-64 chloride). As described herein, the system includes a target material area or target material shape that matches the proton beam strike area or proton beam strike shape, resulting in optimal thickness with less target material required.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2022},
month = {11}
}
Works referenced in this record:
The Installation of a Solid Target System Produced by Newton Scientific on a 168 JSW Baby Cyclotron Capable of Loading and Delivering Multiple Solid Targets with a Single Setup
conference, January 2003
- Gaehle, G.
- AIP Conference Proceedings
High purity production and potential applications of copper-60 and copper-61
journal, May 1999
- McCarthy, Deborah W.; Bass, Laura A.; Cutler, P. Duffy
- Nuclear Medicine and Biology, Vol. 26, Issue 4
Production of .sup.64 Cu and other radionuclides using a charged-particle accelerator
patent, January 2000
- Welch, Michael J.; McCarthy, Deborah; Shefer, Ruth
- US Patent Document 6,011,825
Simultaneous production of high specific activity 64Cu and 61Co with 11.4MeV protons on enriched 64Ni nuclei
journal, October 2007
- Avila-Rodriguez, Miguel A.; Nye, Jonathon A.; Nickles, Robert J.
- Applied Radiation and Isotopes, Vol. 65, Issue 10
Module-assisted preparation of 64Cu with high specific activity
journal, April 2012
- Thieme, S.; Walther, M.; Pietzsch, H. -J.
- Applied Radiation and Isotopes, Vol. 70, Issue 4
Alternative method for 64Cu radioisotope production
journal, July 2009
- Le, Van So; Howse, J.; Zaw, M.
- Applied Radiation and Isotopes, Vol. 67, Issue 7-8
Efficient preparation of high-quality 64Cu for routine use
journal, November 2016
- Ohya, Tomoyuki; Nagatsu, Kotaro; Suzuki, Hisashi
- Nuclear Medicine and Biology, Vol. 43, Issue 11
Automation of 64Cu production at Turku PET Centre
journal, July 2014
- Elomaa, Viki-Veikko; Jurttila, Jori; Rajander, Johan
- Applied Radiation and Isotopes, Vol. 89
Establishing Reliable Cu-64 Production Process: From Target Plating to Molecular Specific Tumor Micro-PET Imaging
journal, April 2017
- Xie, Qinghua; Zhu, Hua; Wang, Feng
- Molecules, Vol. 22, Issue 4
Automated Separation, Purification and Labeling System for 60CU, 61CU and 64CU Radionuclides and Recovery Thereof
patent-application, January 2006
- Welch, Michael John; Tang, Lucie Li Wa; Gaehle, Gregory Glen
- US Patent Application 10/914617; 20060004491
Radiosynthesis and quality control of [ 11 C]TASP457 as a clinically useful PET ligand for imaging of histamine H 3 receptors in human brain
journal, November 2016
- Hanyu, Masayuki; Kawamura, Kazunori; Takei, Makoto
- Nuclear Medicine and Biology, Vol. 43, Issue 11
A semi-automated system for the routine production of copper-64
journal, August 2012
- Kume, Maiko; Carey, Paul C.; Gaehle, Gregory
- Applied Radiation and Isotopes, Vol. 70, Issue 8
A simple and efficient method of nickel electrodeposition for the cyclotron production of 64Cu
journal, July 2014
- Manrique-Arias, Juan C.; Avila-Rodriguez, Miguel A.
- Applied Radiation and Isotopes, Vol. 89