Biosynthetic platform for the production of cannabinoids and other prenylated compounds

Bowie, James U.; Valliere, Meaghan; Korman, Tyler P.; Woodall, Nicholas

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A - human necessities
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A21 - baking
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Title: Biosynthetic platform for the production of cannabinoids and other prenylated compounds

Abstract

Provided is an enzyme useful for prenylation and recombinant pathways for the production of cannabinoids, cannabinoid precursors and other prenylated chemicals in a cell free system as well and recombinant microorganisms that catalyze the reactions.

Inventors:: Bowie, James U.; Valliere, Meaghan; Korman, Tyler P.; Woodall, Nicholas

Issue Date:: 2022-10-25

Research Org.:: Univ. of California, Los Angeles, CA (United States)

Sponsoring Org.:: USDOE; National Institutes of Health (NIH)

OSTI Identifier:: 1986733

Patent Number(s):: 11479760

Application Number:: 17/264,758

Assignee:: The Regents of the University of California (Oakland, CA)

DOE Contract Number:: FC02-02ER63421; GM008496

Resource Type:: Patent

Resource Relation:: Patent File Date: 08/01/2019

Country of Publication:: United States

Language:: English

Citation Formats


                    Bowie, James U., Valliere, Meaghan, Korman, Tyler P., and Woodall, Nicholas. Biosynthetic platform for the production of cannabinoids and other prenylated compounds.  United States: N. p., 2022. 
        Web.

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                    Bowie, James U., Valliere, Meaghan, Korman, Tyler P., & Woodall, Nicholas. Biosynthetic platform for the production of cannabinoids and other prenylated compounds.  United States.

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                    Bowie, James U., Valliere, Meaghan, Korman, Tyler P., and Woodall, Nicholas. Tue .  
        "Biosynthetic platform for the production of cannabinoids and other prenylated compounds".  United States.  https://www.osti.gov/servlets/purl/1986733.

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@article{osti_1986733,

  title        = {Biosynthetic platform for the production of cannabinoids and other prenylated compounds},

  author       = {Bowie, James U. and Valliere, Meaghan and Korman, Tyler P. and Woodall, Nicholas},

  abstractNote = {Provided is an enzyme useful for prenylation and recombinant pathways for the production of cannabinoids, cannabinoid precursors and other prenylated chemicals in a cell free system as well and recombinant microorganisms that catalyze the reactions.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2022},

  month        = {10}

}

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Works referenced in this record:

Structure-Based Engineering Increased the Catalytic Turnover Rate of a Novel Phenazine Prenyltransferase
journal, October 2012

Zocher, Georg; Saleh, Orwah; Heim, Joel B.
PLoS ONE, Vol. 7, Issue 10
https://doi.org/10.1371/journal.pone.0048427

Catalytic Mechanism of Aromatic Prenylation by NphB
journal, March 2012

Yang, Yue; Miao, Yipu; Wang, Bing
Biochemistry, Vol. 51, Issue 12
https://doi.org/10.1021/bi201800m

Novel Aromatic Prenyltransferases, Nucleic Acids Encoding Same and Uses Thereof
patent-application, November 2010

Kuzuyama, Tomohisa; Noel, Joseph P.; Richard, Stephane P.
US Patent Application 12/480618; 20100285502
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20100285502