DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Multi-channel pulsed valve inlet system and method

Abstract

A multichannel inlet system for a mass spectrometer includes a plurality of valve assemblies coupled to a manifold, and a pulsed valve driver. The manifold is configured to be connected in fluid connection with an ion trap of the mass spectrometer. Each valve assembly includes a valve and an injection port operably coupled to receive the reagent. The valve has an actuated state in which the valve provides fluid communication between the injection port and the manifold, and an unactuated state in which the valve substantially prevents fluid communication between the injection port and the manifold. The pulsed valve driver is operably connected to receive a pulse signal sequence from a processor, and is configured to generate pulsed valve drive signals for one or more of the valves based on the pulse signal sequence to cause a corresponding one of the valves to be in the actuated state.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Purdue Univ., West Lafayette, IN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1986693
Patent Number(s):
11469092
Application Number:
16/855,625
Assignee:
Purdue Research Foundation (West Lafayette, IN)
DOE Contract Number:  
SC0000997
Resource Type:
Patent
Resource Relation:
Patent File Date: 04/22/2020
Country of Publication:
United States
Language:
English

Citation Formats

Kenttamaa, Hilkka, Hilger, Ryan, Yerabolu, Ravikiran, Kong, John, Prentice, Tiffany, and Jin, Chunfen. Multi-channel pulsed valve inlet system and method. United States: N. p., 2022. Web.
Kenttamaa, Hilkka, Hilger, Ryan, Yerabolu, Ravikiran, Kong, John, Prentice, Tiffany, & Jin, Chunfen. Multi-channel pulsed valve inlet system and method. United States.
Kenttamaa, Hilkka, Hilger, Ryan, Yerabolu, Ravikiran, Kong, John, Prentice, Tiffany, and Jin, Chunfen. Tue . "Multi-channel pulsed valve inlet system and method". United States. https://www.osti.gov/servlets/purl/1986693.
@article{osti_1986693,
title = {Multi-channel pulsed valve inlet system and method},
author = {Kenttamaa, Hilkka and Hilger, Ryan and Yerabolu, Ravikiran and Kong, John and Prentice, Tiffany and Jin, Chunfen},
abstractNote = {A multichannel inlet system for a mass spectrometer includes a plurality of valve assemblies coupled to a manifold, and a pulsed valve driver. The manifold is configured to be connected in fluid connection with an ion trap of the mass spectrometer. Each valve assembly includes a valve and an injection port operably coupled to receive the reagent. The valve has an actuated state in which the valve provides fluid communication between the injection port and the manifold, and an unactuated state in which the valve substantially prevents fluid communication between the injection port and the manifold. The pulsed valve driver is operably connected to receive a pulse signal sequence from a processor, and is configured to generate pulsed valve drive signals for one or more of the valves based on the pulse signal sequence to cause a corresponding one of the valves to be in the actuated state.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2022},
month = {10}
}

Works referenced in this record:

Estimation of effective ion temperatures in a quadrupole ion trap
journal, August 1998


Multiple sample introduction mass spectrometry
patent, March 2001


Atmospheric pressure ion source for mass spectrometry
patent, December 2011


Internal pulsed valve sample introduction on a quadrupole ion trap mass spectrometer
journal, October 1995


Comparison of Functional Group Selective Ion–Molecule Reactions of Trimethyl Borate in Different Ion Trap Mass Spectrometers
journal, February 2011


Principles of collisional activation in analytical mass spectrometry
journal, September 1992


Method for Cooling Ions in a Linear Ion Trap
patent-application, July 2011


Multiple electrospray probe interface for mass spectrometry
patent, October 2008


Mass spectrometer with a plurality of ionization probes
patent, December 2002


Ozone-Induced Dissociation on a Modified Tandem Linear Ion-Trap: Observations of Different Reactivity for Isomeric Lipids
journal, December 2010


Methods for Fragmenting Ions in a Linear Ion Trap
patent-application, August 2009


Method of Operating a Linear Ion Trap to Provide Low Pressure Short Time High Amplitude Excitation with Pulsed Pressure
patent-application, August 2009


Sensitive Glow Discharge Ion Source for Aerosol and Gas Analysis
patent-application, February 2007


Parallel fluid electrospray mass spectrometer
patent, May 2000


Investigation of the gas phase reactivity of the 1-adamantyl radical using a distonic radical anion approach
journal, January 2007


Functional Group Selective Ion/Molecule Reactions:  Mass Spectrometric Identification of the Amido Functionality in Protonated Monofunctional Compounds
journal, April 2007


Pulsed gas introduction into quadrupole ion traps
journal, July 1990


Cryogenic 2D Linear Ion Trap and Uses Thereof
patent-application, November 2018


A two-dimensional quadrupole ion trap mass spectrometer
journal, June 2002