Shape memory embolectomy devices and systems
Abstract
An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States); Texas A & M Univ., College Station, TX (United States)
- Sponsoring Org.:
- USDOE; National Institute of Biomedical Imaging and Bioengineering
- OSTI Identifier:
- 1924956
- Patent Number(s):
- 11406401
- Application Number:
- 16/701,417
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA); The Texas A&M University System (College Station, TX)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
- DOE Contract Number:
- AC52-07NA27344; R01EB000462
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 12/03/2019
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Szafron, Jason, Maitland, Duncan, Small, IV, Ward, Buckley, Patrick R., and Muschenborn, Andrea D. Shape memory embolectomy devices and systems. United States: N. p., 2022.
Web.
Szafron, Jason, Maitland, Duncan, Small, IV, Ward, Buckley, Patrick R., & Muschenborn, Andrea D. Shape memory embolectomy devices and systems. United States.
Szafron, Jason, Maitland, Duncan, Small, IV, Ward, Buckley, Patrick R., and Muschenborn, Andrea D. Tue .
"Shape memory embolectomy devices and systems". United States. https://www.osti.gov/servlets/purl/1924956.
@article{osti_1924956,
title = {Shape memory embolectomy devices and systems},
author = {Szafron, Jason and Maitland, Duncan and Small, IV, Ward and Buckley, Patrick R. and Muschenborn, Andrea D.},
abstractNote = {An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2022},
month = {8}
}
Works referenced in this record:
Clot Capture Systems and Associated Methods
patent-application, May 2011
- Brady, Eamon; Razavi, Mahmood; Vale, David
- US Patent Application 12/737,527; 2011/0125181 Al
Device And Method For Treatment Of Openings In Vascular And Septal Walls
patent-application, November 2013
- Singhal, Pooja; Wilson, Thomas S.; Cosgriff-Hernandez, Elizabeth
- US Patent Application 13/797727; 20130317541
Septal Closure Device with Centering Mechanism
patent-application, July 2015
- Cahill, Ryan
- US Patent Application 14/642,238; 2015/0182209 Al
Embolectomy devices
patent-application, October 2004
- Kellett, James; Sontrop, Valerie; Welsh, Greg
- US Patent Application 10/698760; 20040199201
Embolus removal device with blood flow restriction and related methods
patent-application, June 2015
- Ma, Jianlu
- US Patent Application 14/598705; 20150150672
Rotating shaft containing optical waveguide
patent-application, December 2013
- Le, Anthony Van; Richardi, Nicholas John
- US Patent Application 13/491538; 20130331689
Ultra Low Density Biodegradable Shape Memory Polymer Foams With Tunable Physical Properties
patent-application, May 2014
- Singhal, Pooja; Wilson, Thomas S.; Cosgriff-Hernandez, Elizabeth
- US Patent Application 13/797631; 20140142207
Design and Characterization of an Endovascular Mechanical Thrombectomy Device1
journal, April 2014
- Szafron, Jason M.; Muschenborn, Andrea D.; Maitland, Duncan J.
- Journal of Medical Devices, Vol. 8, Issue 2
Shape-memory polymers and their composites: Stimulus methods and applications
journal, September 2011
- Leng, Jinsong; Lan, Xin; Liu, Yanju
- Progress in Materials Science, Vol. 56, Issue 7
Shape memory polymer actuator and catheter
patent, May 2004
- Maitland, Duncan J.; Lee, Abraham P.; Schumann, Daniel L.
- US Patent Document 6,740,094
Methods and Apparatus for Treating Embolism
patent-application, October 2015
- Rosenbluth, Robert; Cox, Brian J.; Lubock, Paul
- US Patent Application 14/646,358; 2015/0305756 Al
Guide wire extension for shape memory polymer occlusion removal devices
patent, November 2009
- Maitland, Duncan J.; Small, IV, Ward; Hartman, Jonathan
- US Patent Document 7,611,524
Ultra low density and highly crosslinked biocompatible shape memory polyurethane foams
journal, March 2012
- Singhal, Pooja; Rodriguez, Jennifer N.; Small, Ward
- Journal of Polymer Science Part B: Polymer Physics, Vol. 50, Issue 10, p. 724-737
Shape memory polymer foams for endovascular therapies
patent, May 2015
- Wilson, Thomas S.; Maitland, Duncan J.
- US Patent Document 9,039,733
Shape memory polymer medical device
patent, June 2010
- Maitland, Duncan J.; Benett, William J.; Bearinger, Jane P.
- US Patent Document 7,744,604
Devices and Methods for Removing a Matter from a Body Cavity of a Patient
patent-application, February 2008
- Teitelbaum, George P.; Larsen, Donald W.
- US Patent Application 11/829,879; 2008/0045881 Al