Title: Synthesis of bioproducts from lignin-derived aromatics by genetically modified microorganisms

Abstract

The present invention provides for a method of converting a depolymerized lignin aromatic compound into a bioproduct, comprising: (a) providing a composition comprising a depolymerized lignin aromatic compound, optionally a depolymerized cellulose, and optionally a depolymerized hemicellulose, and (b) introducing a genetically modified microorganism to the composition, wherein the genetically modified microorganism is capable of converting the depolymerized lignin aromatic compound into a bioproduct; such that the depolymerized lignin aromatic compound is converted into a bioproduct.

Inventors:

Gladden, John M.; Skerker, Jeffrey M.; Keasling, Jay D.; Kirby, James; Yaegashi, Junko

Issue Date:

2022-07-12

Research Org.:

Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1924888

Patent Number(s):

11384367

Application Number:

16/450,824

Assignee:

The Regents of the University of California (Oakland, CA); National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM); Battelle Memorial Institute (For Management and Operation of Pacific Northwest National Laboratory) (Richland, WA)

Patent Classifications (CPCs):

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07G - COMPOUNDS OF UNKNOWN CONSTITUTION

C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08H - DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS

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C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07G - COMPOUNDS OF UNKNOWN CONSTITUTION

C07G1/00 - Lignin

C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08H - DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS

C08H6/00 - {Macromolecular compounds derived from lignin, e.g. tannins, humic acids}

C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08L - COMPOSITIONS OF MACROMOLECULAR COMPOUNDS

C08L97/005 - {Lignin}

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

C12P1/02 - by using fungi
C12P13/227 - {Tryptophan}
C12P17/182 - {Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
C12P5/007 - {containing one or more isoprene units, i.e. terpenes
C12P7/42 - Hydroxy-carboxylic acids
C12P7/649 - {Biodiesel, i.e. Fatty acid alkyl esters}

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION

Y02E50/10 - Biofuels

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DOE Contract Number:  

AC02-05CH11231

Resource Type:

Patent

Resource Relation:

Patent File Date: 06/24/2019

Country of Publication:

United States

Language:

English