Title: Microfluidic aspirator and multi-purpose flow sensor and methods of making and using the same

Abstract

Devices that include a liquid chamber including at least two ports, wherein the opening of a first port is larger than the opening of a second port, an air chamber including at least one port, and a membrane located between the liquid chamber and the air chamber, and a pressure sensor coupled to the port in the air chamber are provided. Systems including the disclosed devices are also provided. The systems include liquid in the liquid chamber of the device. Methods of using the devices and systems include measuring one or more properties of a liquid by flowing the liquid through the liquid chamber of the system and measuring the pressure produced due to the difference in size of the ports in the liquid chamber.

Inventors:

Nath, Pulak; McFall, Jackson Henry; Purcell, Dylan Chance; Huang, Jen-Lung

Issue Date:

2022-03-29

Research Org.:

Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)

Sponsoring Org.:

USDOE National Nuclear Security Administration (NNSA)

OSTI Identifier:

1892755

Patent Number(s):

11287358

Application Number:

16/538,561

Assignee:

Triad National Security, LLC (Los Alamos, NM)

Patent Classifications (CPCs):

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

F - MECHANICAL ENGINEERING F04 - POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS F04B - POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

B01L2200/146 - Employing pressure sensors
B01L2300/0663 - Whole sensors
B01L2400/0487 - fluid pressure, pneumatics

F - MECHANICAL ENGINEERING F04 - POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS F04B - POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS

F04B45/043 - {two or more plate-like pumping flexible members in parallel}
F04B45/0536 - {the actuating fluid being controlled by one or more valves}

G - PHYSICS G01 - MEASURING G01F - MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL

G01F1/34 - by measuring pressure or differential pressure
G01F1/72 - Devices for measuring pulsing fluid flows
G01F1/74 - Devices for measuring flow of a fluid or flow of a fluent solid material in suspension in another fluid

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N1/14 - Suction devices, e.g. pumps
G01N11/08 - by measuring pressure required to produce a known flow
G01N33/5044 - {involving specific cell types}

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DOE Contract Number:  

89233218CNA000001

Resource Type:

Patent

Resource Relation:

Patent File Date: 08/12/2019

Country of Publication:

United States

Language:

English

Subject:

47 OTHER INSTRUMENTATION; 42 ENGINEERING