Microscopy imaging device with advanced imaging properties
Abstract
Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.
- Inventors:
- Issue Date:
- Research Org.:
- Stanford Univ., CA (United States); Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1892653
- Patent Number(s):
- 11259703
- Application Number:
- 17/080,295
- Assignee:
- The Board of Trustees of the Leland Stanford Junior University (Stanford, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC52-07NA27344
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 10/26/2020
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Ghosh, Kunal, Burns, Laurie D., El Gamal, Abbas, Schnitzer, Mark J., Cocker, Eric, and Ho, Tatt Wei. Microscopy imaging device with advanced imaging properties. United States: N. p., 2022.
Web.
Ghosh, Kunal, Burns, Laurie D., El Gamal, Abbas, Schnitzer, Mark J., Cocker, Eric, & Ho, Tatt Wei. Microscopy imaging device with advanced imaging properties. United States.
Ghosh, Kunal, Burns, Laurie D., El Gamal, Abbas, Schnitzer, Mark J., Cocker, Eric, and Ho, Tatt Wei. Tue .
"Microscopy imaging device with advanced imaging properties". United States. https://www.osti.gov/servlets/purl/1892653.
@article{osti_1892653,
title = {Microscopy imaging device with advanced imaging properties},
author = {Ghosh, Kunal and Burns, Laurie D. and El Gamal, Abbas and Schnitzer, Mark J. and Cocker, Eric and Ho, Tatt Wei},
abstractNote = {Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2022},
month = {3}
}
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