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Title: Compact assembly for production of medical isotopes via photonuclear reactions

Abstract

The invention provides a method for generating medical isotopes, the method comprising contacting a primary radiation beam with a converter for a time sufficient to produce a secondary beam of gamma particles, and contacting the beam of gamma particles to a target, where the cross section dimension of the beam of gamma particles is similar to the cross section dimension of the target. Both the converter and target are small in diameter and very closely spaced. Also provided is a system for producing medical isotopes, the device comprising a housing having a first upstream end and a second downstream end, a radiotransparent channel (collimator) with a first upstream end and a downstream end, wherein the upstream end is adapted to receive a radiation beam, a target positioned downstream of the downstream end of the channel and coaxially aligned with the channel, wherein the target has a cross section that is similar to the cross section of the channel.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1892510
Patent Number(s):
11217355
Application Number:
16/146,975
Assignee:
UChicago Argonne, LLC (Chicago, IL)
Patent Classifications (CPCs):
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
G - PHYSICS G21 - NUCLEAR PHYSICS G21K - TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR
DOE Contract Number:  
AC02-06CH11357
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/28/2018
Country of Publication:
United States
Language:
English

Citation Formats

Nolen, Jr., Jerry A., Brown, Michael Alexander, Rotsch, David A., Chemerisov, Sergey D., Henning, Walter F., and Song, Jeongseog. Compact assembly for production of medical isotopes via photonuclear reactions. United States: N. p., 2022. Web.
Nolen, Jr., Jerry A., Brown, Michael Alexander, Rotsch, David A., Chemerisov, Sergey D., Henning, Walter F., & Song, Jeongseog. Compact assembly for production of medical isotopes via photonuclear reactions. United States.
Nolen, Jr., Jerry A., Brown, Michael Alexander, Rotsch, David A., Chemerisov, Sergey D., Henning, Walter F., and Song, Jeongseog. Tue . "Compact assembly for production of medical isotopes via photonuclear reactions". United States. https://www.osti.gov/servlets/purl/1892510.
@article{osti_1892510,
title = {Compact assembly for production of medical isotopes via photonuclear reactions},
author = {Nolen, Jr., Jerry A. and Brown, Michael Alexander and Rotsch, David A. and Chemerisov, Sergey D. and Henning, Walter F. and Song, Jeongseog},
abstractNote = {The invention provides a method for generating medical isotopes, the method comprising contacting a primary radiation beam with a converter for a time sufficient to produce a secondary beam of gamma particles, and contacting the beam of gamma particles to a target, where the cross section dimension of the beam of gamma particles is similar to the cross section dimension of the target. Both the converter and target are small in diameter and very closely spaced. Also provided is a system for producing medical isotopes, the device comprising a housing having a first upstream end and a second downstream end, a radiotransparent channel (collimator) with a first upstream end and a downstream end, wherein the upstream end is adapted to receive a radiation beam, a target positioned downstream of the downstream end of the channel and coaxially aligned with the channel, wherein the target has a cross section that is similar to the cross section of the channel.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2022},
month = {1}
}

Works referenced in this record:

Production of isotopes using high power proton beams
patent, December 2015


Method for producing Ac-225 by irradiation of Ra-226 with protons
patent, October 2001


Production of Molybdenum-99 Using Electron Beams
patent-application, November 2014


Preparation of 225Ac by 226Ra(γ, n) photonuclear reaction on an electron accelerator, MT-25 microtron
journal, March 2006


Method of producing molybdenum-99
patent, July 1998