Alpha(v)beta(6) integrin-binding peptides and methods of use thereof
Abstract
The present invention provides peptide conjugates that target an integrin such as αvβ6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE; National Institutes of Health (NIH)
- OSTI Identifier:
- 1860108
- Patent Number(s):
- 11185601
- Application Number:
- 16/217,397
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- EB012836; SC0002061
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 12/12/2018
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Tang, Yng, and Sutcliffe, Julie L. Alpha(v)beta(6) integrin-binding peptides and methods of use thereof. United States: N. p., 2021.
Web.
Tang, Yng, & Sutcliffe, Julie L. Alpha(v)beta(6) integrin-binding peptides and methods of use thereof. United States.
Tang, Yng, and Sutcliffe, Julie L. Tue .
"Alpha(v)beta(6) integrin-binding peptides and methods of use thereof". United States. https://www.osti.gov/servlets/purl/1860108.
@article{osti_1860108,
title = {Alpha(v)beta(6) integrin-binding peptides and methods of use thereof},
author = {Tang, Yng and Sutcliffe, Julie L.},
abstractNote = {The present invention provides peptide conjugates that target an integrin such as αvβ6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 30 00:00:00 EST 2021},
month = {Tue Nov 30 00:00:00 EST 2021}
}
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