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Title: Alpha(v)beta(6) integrin-binding peptides and methods of use thereof

Abstract

The present invention provides peptide conjugates that target an integrin such as αvβ6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.

Inventors:
;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE; National Institutes of Health (NIH)
OSTI Identifier:
1860108
Patent Number(s):
11185601
Application Number:
16/217,397
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
EB012836; SC0002061
Resource Type:
Patent
Resource Relation:
Patent File Date: 12/12/2018
Country of Publication:
United States
Language:
English

Citation Formats

Tang, Yng, and Sutcliffe, Julie L. Alpha(v)beta(6) integrin-binding peptides and methods of use thereof. United States: N. p., 2021. Web.
Tang, Yng, & Sutcliffe, Julie L. Alpha(v)beta(6) integrin-binding peptides and methods of use thereof. United States.
Tang, Yng, and Sutcliffe, Julie L. Tue . "Alpha(v)beta(6) integrin-binding peptides and methods of use thereof". United States. https://www.osti.gov/servlets/purl/1860108.
@article{osti_1860108,
title = {Alpha(v)beta(6) integrin-binding peptides and methods of use thereof},
author = {Tang, Yng and Sutcliffe, Julie L.},
abstractNote = {The present invention provides peptide conjugates that target an integrin such as αvβ6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {11}
}

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