Laser ablation sampling system and method

Kertesz, Vilmos; Srijanto, Bernadeta R.; Collier, Charles Patrick; Cahill, John F.

Title: Laser ablation sampling system and method

Abstract

A method and system for sampling a solid sample material can include the step of mounting the sample material on a support. A sample surface is coated with a surface treatment composition in a dry deposition process. A solvent supply conduit for supplying solvent to the sample surface and a solvent exhaust conduit for withdrawing solvent from the sample surface can be provided. Solvent is flowed from the solvent supply conduit to the surface treatment composition and the sample surface such that the solvent contacts the surface treatment composition. A laser beam is directed from a laser source to the sample and the surface treatment composition. The laser beam will ablate the sample and the surface treatment composition in portions intersected by the laser beam. Ablated sample material enters the solvent liquid and will be transported with the solvent away from the sample surface through the solvent exhaust conduit.

Inventors:: Kertesz, Vilmos; Srijanto, Bernadeta R.; Collier, Charles Patrick; Cahill, John F.

Issue Date:: 2021-11-23

Research Org.:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1860097

Patent Number(s):: 11181446

Application Number:: 16/797,712

Assignee:: UT-Battelle, LLC (Oak Ridge, TN)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS

Show more

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N1/04 - in the solid state, e.g. by cutting
G01N1/38 - Diluting, dispersing or mixing samples
G01N2001/045 - {Laser ablation
G01N2001/383 - {collecting and diluting in a flow of liquid}

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
H01J49/0463 - {Desorption by laser or particle beam, followed by ionisation as a separate step
H01J49/164 - {Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]

Show less

DOE Contract Number:: AC05-00OR22725

Resource Type:: Patent

Resource Relation:: Patent File Date: 02/21/2020

Country of Publication:: United States

Language:: English

Citation Formats


                    Kertesz, Vilmos, Srijanto, Bernadeta R., Collier, Charles Patrick, and Cahill, John F.. Laser ablation sampling system and method.  United States: N. p., 2021. 
        Web.

Copy to clipboard


                    Kertesz, Vilmos, Srijanto, Bernadeta R., Collier, Charles Patrick, & Cahill, John F.. Laser ablation sampling system and method.  United States.

Copy to clipboard


                    Kertesz, Vilmos, Srijanto, Bernadeta R., Collier, Charles Patrick, and Cahill, John F.. Tue .  
        "Laser ablation sampling system and method".  United States.  https://www.osti.gov/servlets/purl/1860097.

Copy to clipboard


                    
@article{osti_1860097,

  title        = {Laser ablation sampling system and method},

  author       = {Kertesz, Vilmos and Srijanto, Bernadeta R. and Collier, Charles Patrick and Cahill, John F.},

  abstractNote = {A method and system for sampling a solid sample material can include the step of mounting the sample material on a support. A sample surface is coated with a surface treatment composition in a dry deposition process. A solvent supply conduit for supplying solvent to the sample surface and a solvent exhaust conduit for withdrawing solvent from the sample surface can be provided. Solvent is flowed from the solvent supply conduit to the surface treatment composition and the sample surface such that the solvent contacts the surface treatment composition. A laser beam is directed from a laser source to the sample and the surface treatment composition. The laser beam will ablate the sample and the surface treatment composition in portions intersected by the laser beam. Ablated sample material enters the solvent liquid and will be transported with the solvent away from the sample surface through the solvent exhaust conduit.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2021},

  month        = {11}

}

Copy to clipboard

Patent:

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, June 2014

Van Berkel, Gary J.; Kertesz, Vilmos; Ovchinnikova, Olga S.
US Patent Document 8,742,338
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8742338

Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, August 2013

Van Berkel, Gary J.; Kertesz, Vilmos; Ovchinnikova, Olga S.
US Patent Document 8,519,330
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8519330

Superhydrophobic transparent glass (stg) thin film articles
patent-application, April 2012

Aytug, Tolga; Simpson, John; Christen, David
US Patent Application 12/915183; 20120088066
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20120088066

System and Method for Liquid Extraction Electrospray-Assisted Sample Transfer to Solution for Chemical Analysis
patent-application, May 2016

Kertesz, Vilmos; Van Berkel, Gary J.
US Patent Application 14/529307; 20160126080
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20160126080

Laser Ablation Sampling of Materials Directly into the Formed Liquid Microjunction of a Continuous Flow Surface Sampling Probe/Electrospray Ionization Emitter for Mass Spectral Analysis and Imaging
journal, October 2013

Ovchinnikova, Olga S.; Lorenz, Matthias; Kertesz, Vilmos
Analytical Chemistry, Vol. 85, Issue 21
https://doi.org/10.1021/ac4018499

Fabrication, performance testing, and screening of three dimensional arrays of materials
patent-application, August 2003

Potyrailo, Radislav ALexandrovich; Cawse, James Norman
US Patent Application 10/083727; 20030162179
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20030162179

Combining transmission geometry laser ablation and a non-contact continuous flow surface sampling probe/electrospray emitter for mass spectrometry based chemical imaging: Laser ablation/surface sampling probe chemical imaging
journal, November 2011

Ovchinnikova, Olga S.; Kertesz, Vilmos; Van Berkel, Gary J.
Rapid Communications in Mass Spectrometry, Vol. 25, Issue 24
https://doi.org/10.1002/rcm.5285

Systems and Methods for Laser Assisted sample Transfer to Solution for Chemical Analysis
patent-application, August 2014

Van Berkel, Gary J. .; Kertesz, Vilmos; Ovchinnikova, Olga S.
US Patent Application 14/267482; 20140238155
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140238155

Combining Laser Ablation/Liquid Phase Collection Surface Sampling and High-Performance Liquid Chromatography−Electrospray Ionization-Mass Spectrometry
journal, March 2011

Ovchinnikova, Olga S.; Kertesz, Vilmos; Van Berkel, Gary J.
Analytical Chemistry, Vol. 83, Issue 6
https://doi.org/10.1021/ac200051y

Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, September 2015

Van Berkel, Gary J.; Kertesz, Vilmos; Ovchinnikova, Olga S.
US Patent Document 9,146,180
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9146180

Anti-fingerprint Coatings
patent-application, June 2013

Aytug, Tolga; Simpson, John T.
US Patent Application 13/767244; 20130157008
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130157008

Systems and Methods for Laser Assisted Sample Transfer to Solution for Chemical Analysis
patent-application, November 2013

Van Berkel, Gary J.; Kertesz, Vilmos; Ovchinnikova, Olga S.
US Patent Application 13/949777; 20130298701
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130298701

System and method for laser assisted sample transfer to solution for chemical analysis
patent, January 2014

Van Berkel, Gary J.; Kertesz, Vilmos
US Patent Document 8,637,813
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8637813

Similar Records in DOE Patents and OSTI.GOV collections:

Laser ablation system, and method of decontaminating surfaces

Patent Ferguson, Russell L [Idaho Falls, ID]; Edelson, Martin C [Ames, IA]; Pang, Ho-ming [Ames, IA]

A laser ablation system comprising a laser head providing a laser output; a flexible fiber optic cable optically coupled to the laser output and transmitting laser light; an output optics assembly including a nozzle through which laser light passes; an exhaust tube in communication with the nozzle; and a blower generating a vacuum on the exhaust tube. A method of decontaminating a surface comprising the following steps: providing an acousto-optic, Q-switched Nd:YAG laser light ablation system having a fiber optically coupled output optics assembly; and operating the laser light ablation system to produce an irradiance greater than 1.times.10.sup.7 W/cm.sup.2, andmore » a pulse width between 80 and 170 ns. « less
Full Text Available
System and method for measuring particles in a sample stream of a flow cytometer using low-power laser source

Patent Graves, Steven W.; Habbersett, Robert C.

A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronicmore » « less
Full Text Available
Systems and methods for laser assisted sample transfer to solution for chemical analysis

Patent Van Berkel, Gary J; Kertesz, Vilmos; Ovchinnikova, Olga S

Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed usingmore » « less
Full Text Available
Systems and methods for laser assisted sample transfer to solution for chemical analysis

Patent Van Berkel, Gary J.; Kertesz, Vilmos; Ovchinnikova, Olga S.

Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed usingmore » « less
Full Text Available
Systems and methods for laser assisted sample transfer to solution for chemical analysis

Patent Van Berkel, Gary J.; Kertesz, Vilmos; Ovchinnikova, Olga S.

Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed usingmore » « less
Full Text Available

Similar Records

Title: Laser ablation sampling system and method

Abstract

Citation Formats

Systems and methods for laser assisted sample transfer to solution for chemical analysis patent, June 2014

Systems and methods for laser assisted sample transfer to solution for chemical analysis patent, August 2013

Superhydrophobic transparent glass (stg) thin film articles patent-application, April 2012

System and Method for Liquid Extraction Electrospray-Assisted Sample Transfer to Solution for Chemical Analysis patent-application, May 2016

Laser Ablation Sampling of Materials Directly into the Formed Liquid Microjunction of a Continuous Flow Surface Sampling Probe/Electrospray Ionization Emitter for Mass Spectral Analysis and Imaging journal, October 2013

Fabrication, performance testing, and screening of three dimensional arrays of materials patent-application, August 2003

Combining transmission geometry laser ablation and a non-contact continuous flow surface sampling probe/electrospray emitter for mass spectrometry based chemical imaging: Laser ablation/surface sampling probe chemical imaging journal, November 2011

Systems and Methods for Laser Assisted sample Transfer to Solution for Chemical Analysis patent-application, August 2014

Combining Laser Ablation/Liquid Phase Collection Surface Sampling and High-Performance Liquid Chromatography−Electrospray Ionization-Mass Spectrometry journal, March 2011

Systems and methods for laser assisted sample transfer to solution for chemical analysis patent, September 2015

Anti-fingerprint Coatings patent-application, June 2013

Systems and Methods for Laser Assisted Sample Transfer to Solution for Chemical Analysis patent-application, November 2013

System and method for laser assisted sample transfer to solution for chemical analysis patent, January 2014

Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, June 2014

Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, August 2013

Superhydrophobic transparent glass (stg) thin film articles
patent-application, April 2012

System and Method for Liquid Extraction Electrospray-Assisted Sample Transfer to Solution for Chemical Analysis
patent-application, May 2016

Laser Ablation Sampling of Materials Directly into the Formed Liquid Microjunction of a Continuous Flow Surface Sampling Probe/Electrospray Ionization Emitter for Mass Spectral Analysis and Imaging
journal, October 2013

Fabrication, performance testing, and screening of three dimensional arrays of materials
patent-application, August 2003

Combining transmission geometry laser ablation and a non-contact continuous flow surface sampling probe/electrospray emitter for mass spectrometry based chemical imaging: Laser ablation/surface sampling probe chemical imaging
journal, November 2011

Systems and Methods for Laser Assisted sample Transfer to Solution for Chemical Analysis
patent-application, August 2014

Combining Laser Ablation/Liquid Phase Collection Surface Sampling and High-Performance Liquid Chromatography−Electrospray Ionization-Mass Spectrometry
journal, March 2011

Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, September 2015

Anti-fingerprint Coatings
patent-application, June 2013

Systems and Methods for Laser Assisted Sample Transfer to Solution for Chemical Analysis
patent-application, November 2013

System and method for laser assisted sample transfer to solution for chemical analysis
patent, January 2014