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Title: Function-based probes for environmental microbiome analysis and methods of making and using the same

Abstract

Probe embodiments for identifying analytes involved in biofuel or bioenergy production, bioremediation, or nutrient cycling as well as methods of making and use are described herein. In some embodiments, probes identifying cellulose degradation and/or sugar transport, lignin or chitin degradation, or peptide or toxin metabolism are included. In some embodiments, probes for identifying analytes in a soil sample are included in the compositions and methods disclosed herein.

Inventors:
; ;
Issue Date:
Research Org.:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1860048
Patent Number(s):
11169152
Application Number:
16/132,266
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07H - SUGARS
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/14/2018
Country of Publication:
United States
Language:
English

Citation Formats

Wright, Aaron T., Ramos-Hunter, Susan, and Sadler, Natalie C.. Function-based probes for environmental microbiome analysis and methods of making and using the same. United States: N. p., 2021. Web.
Wright, Aaron T., Ramos-Hunter, Susan, & Sadler, Natalie C.. Function-based probes for environmental microbiome analysis and methods of making and using the same. United States.
Wright, Aaron T., Ramos-Hunter, Susan, and Sadler, Natalie C.. Tue . "Function-based probes for environmental microbiome analysis and methods of making and using the same". United States. https://www.osti.gov/servlets/purl/1860048.
@article{osti_1860048,
title = {Function-based probes for environmental microbiome analysis and methods of making and using the same},
author = {Wright, Aaron T. and Ramos-Hunter, Susan and Sadler, Natalie C.},
abstractNote = {Probe embodiments for identifying analytes involved in biofuel or bioenergy production, bioremediation, or nutrient cycling as well as methods of making and use are described herein. In some embodiments, probes identifying cellulose degradation and/or sugar transport, lignin or chitin degradation, or peptide or toxin metabolism are included. In some embodiments, probes for identifying analytes in a soil sample are included in the compositions and methods disclosed herein.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {11}
}

Works referenced in this record:

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journal, December 2012


A Suite of Activity-Based Probes for Human Cytochrome P450 Enzymes
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Activity-based protein profiling of microbes
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Screening‐based discovery of Aspergillus fumigatus plant‐type chitinase inhibitors
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Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms
journal, January 2010


β-Lactams and β-lactones as activity-based probes in chemical biology
journal, January 2012


Live-Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules
journal, April 2014


Exploring the Binding Proteins of Glycolipids with Bifunctional Chemical Probes
journal, October 2016


Method for isolating or identifying a target protein interacting with a lipid in a cell
patent-application, January 2011