Title: Isolated oleaginous yeast

Abstract

Some aspects provide engineered microbes for oil production. Methods for microbe engineering and for use of engineered microbes are also provided herein. Such engineered microbes exhibit greatly enhanced conversion yields and TAG synthesis and storage properties.

Inventors:

Stephanopoulos, Gregory; Qiao, Kangjian; Xu, Peng

Issue Date:

2021-10-12

Research Org.:

Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1859930

Patent Number(s):

11142770

Application Number:

15/296,148

Assignee:

Massachusetts Institute of Technology (Cambridge, MA)

Patent Classifications (CPCs):

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N1/16 - Yeasts
C12N15/52 - Genes encoding for enzymes or proenzymes
C12N15/81 - for yeasts
C12N2330/51 - Specially adapted vectors
C12N2510/02 - Cells for production
C12N9/1029 - {transferring groups other than amino-acyl groups
C12N9/93 - {Ligases

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

C12P7/64 - Fats

C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES

C12Y203/0102 - Diacylglycerol O-acyltransferase
C12Y604/01002 - Acetyl-CoA carboxylase

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DOE Contract Number:  

SC0008744

Resource Type:

Patent

Resource Relation:

Patent File Date: 10/18/2016

Country of Publication:

United States

Language:

English