Title: Genes involved in astaxanthin biosynthesis

Abstract

The disclosure is directed to nucleic acid, host cell, and polypeptide compositions encoded by the unicellular green alga Chromochloris zofingiensis, methods of making such compositions, and method of using the compositions to produce astaxanthin.

Inventors:

Roth, Melissa S.; Niyogi, Krishna K.; Gallaher, Sean D.; Merchant, Sabeeha

Issue Date:

2021-09-21

Research Org.:

Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Org.:

USDOE; US Dept. of Agriculture (USDA)

OSTI Identifier:

1840467

Patent Number(s):

11124819

Application Number:

15/922,763

Assignee:

The Regents of the University of California (Oakland, CA)

Patent Classifications (CPCs):

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N1/12 - Unicellular algae
C12N15/52 - Genes encoding for enzymes or proenzymes
C12N15/67 - General methods for enhancing the expression
C12N15/79 - Vectors or expression systems specially adapted for eukaryotic hosts
C12N9/1025 - {Acyltransferases

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

C12P23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES

C12Y203/0102 - Diacylglycerol O-acyltransferase
C12Y203/0104 - Acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase
C12Y203/01158 - Phospholipid

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DOE Contract Number:  

2013-67012-21272; AC02-05CH11231

Resource Type:

Patent

Resource Relation:

Patent File Date: 03/15/2018

Country of Publication:

United States

Language:

English