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Title: Spectroscopy imaging and analysis of live cells

Abstract

Disclosed herein are systems, methods, systems and devices for measurement and visualization of chemical dynamics in living cells or tissues for diagnostic pathology. Devices can be open- or closed-channel microfluidic membrane devices for long-term IR spectroscopy of live adherent cells and ultimately for rapidly identifying time-dependent spectral features indicative of chemical abnormality in individual cells.

Inventors:
; ;
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1840232
Patent Number(s):
11054367
Application Number:
15/766,594
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 10/11/2016
Country of Publication:
United States
Language:
English

Citation Formats

Holman, Hoi-Ying N., Loutherback, Kevin, and Chen, Liang. Spectroscopy imaging and analysis of live cells. United States: N. p., 2021. Web.
Holman, Hoi-Ying N., Loutherback, Kevin, & Chen, Liang. Spectroscopy imaging and analysis of live cells. United States.
Holman, Hoi-Ying N., Loutherback, Kevin, and Chen, Liang. Tue . "Spectroscopy imaging and analysis of live cells". United States. https://www.osti.gov/servlets/purl/1840232.
@article{osti_1840232,
title = {Spectroscopy imaging and analysis of live cells},
author = {Holman, Hoi-Ying N. and Loutherback, Kevin and Chen, Liang},
abstractNote = {Disclosed herein are systems, methods, systems and devices for measurement and visualization of chemical dynamics in living cells or tissues for diagnostic pathology. Devices can be open- or closed-channel microfluidic membrane devices for long-term IR spectroscopy of live adherent cells and ultimately for rapidly identifying time-dependent spectral features indicative of chemical abnormality in individual cells.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {7}
}

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