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Title: Self-assembling peptide polymer

Abstract

A self-assembling peptide is provided that is enzymatically oxidized to form a polymeric pigment. The monomeric peptide has three amino acids (tyrosine (Y), one phenylalanine (F), and one aspartic acid (D) or one lysine (K)) and, following self-assembly and treatment with a tyrosinase enzyme oxidizes and polymerizes into a material with predetermined properties.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE; National Science Foundation (NSF); US Air Force Office of Scientific Research (AFOSR)
OSTI Identifier:
1824014
Patent Number(s):
11021516
Application Number:
16/332,231
Assignee:
The Research Foundation for The State University of New York (New York, NY); University of Strathclyde (Glasgow, GB); Carnegie Mellon University (Pittsburgh, PA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
DOE Contract Number:  
AC02-06CH11357; CHE-1346572; DMR-0820341; DMR-1420073; FA9550-15-1-0192
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/11/2017
Country of Publication:
United States
Language:
English

Citation Formats

Ulijn, Rein Vincent, Lampel, Ayala, Tuttle, Tell, Scott, Gary K., McPhee, Scott, and Bettinger, Christopher J. Self-assembling peptide polymer. United States: N. p., 2021. Web.
Ulijn, Rein Vincent, Lampel, Ayala, Tuttle, Tell, Scott, Gary K., McPhee, Scott, & Bettinger, Christopher J. Self-assembling peptide polymer. United States.
Ulijn, Rein Vincent, Lampel, Ayala, Tuttle, Tell, Scott, Gary K., McPhee, Scott, and Bettinger, Christopher J. Tue . "Self-assembling peptide polymer". United States. https://www.osti.gov/servlets/purl/1824014.
@article{osti_1824014,
title = {Self-assembling peptide polymer},
author = {Ulijn, Rein Vincent and Lampel, Ayala and Tuttle, Tell and Scott, Gary K. and McPhee, Scott and Bettinger, Christopher J.},
abstractNote = {A self-assembling peptide is provided that is enzymatically oxidized to form a polymeric pigment. The monomeric peptide has three amino acids (tyrosine (Y), one phenylalanine (F), and one aspartic acid (D) or one lysine (K)) and, following self-assembly and treatment with a tyrosinase enzyme oxidizes and polymerizes into a material with predetermined properties.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {6}
}

Works referenced in this record:

Self-assembling Peptide Amphiphiles and Related Methods for Growth Factor Delivery
patent-application, September 2005


Color Reaction Using Tyrosinase and Peptide
patent-application, August 2013


Self-assembled peptide-amphiphiles & self-assembled peptide nanofiber networks presenting multiple signals
patent-application, December 2005


Synthetic amino acid-and/or peptide-containing graft copolymers
patent, March 1990


Color reaction using tyrosinase and peptide
patent, May 2014