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Title: Means and methods for treating copper-related diseases

Abstract

The present invention relates to the field of (bio-)medicine, and more particularly to the treatment of copper-related diseases. Novel means and methods for depleting (excess) copper from organs and/or the circulation are provided. Agents with a high copper binding affinity and stabilized forms thereof are provided, as well as a novel treatment regimen. The means and methods of the present invention are particularly useful for treatment of Wilson Disease, but also for treatment of other conditions.

Inventors:
; ; ;
Issue Date:
Research Org.:
Helmholtzzentrum Munchen (Germany); Univ. of Michigan, Ann Arbor, MI (United States); Iowa State Univ., Ames, IA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1823931
Patent Number(s):
11000568
Application Number:
16/063,220
Assignee:
Helmholtz Zentrum Munchen--Deutsches Forschungszentrum fur Gesundheit und Umwelt (GMBH) (Neuhergerg, DE); Iowa State University Research Foundation, Inc. (Ames, IA); The Regents of the University of Michigan (Ames, IA)
DOE Contract Number:  
SC0006630
Resource Type:
Patent
Resource Relation:
Patent File Date: 12/16/2016
Country of Publication:
United States
Language:
English

Citation Formats

Zischka, Hans, Lichtmannegger, Josef, DiSpirito, Alan Angela, and Semrau, Jeremy David. Means and methods for treating copper-related diseases. United States: N. p., 2021. Web.
Zischka, Hans, Lichtmannegger, Josef, DiSpirito, Alan Angela, & Semrau, Jeremy David. Means and methods for treating copper-related diseases. United States.
Zischka, Hans, Lichtmannegger, Josef, DiSpirito, Alan Angela, and Semrau, Jeremy David. Tue . "Means and methods for treating copper-related diseases". United States. https://www.osti.gov/servlets/purl/1823931.
@article{osti_1823931,
title = {Means and methods for treating copper-related diseases},
author = {Zischka, Hans and Lichtmannegger, Josef and DiSpirito, Alan Angela and Semrau, Jeremy David},
abstractNote = {The present invention relates to the field of (bio-)medicine, and more particularly to the treatment of copper-related diseases. Novel means and methods for depleting (excess) copper from organs and/or the circulation are provided. Agents with a high copper binding affinity and stabilized forms thereof are provided, as well as a novel treatment regimen. The means and methods of the present invention are particularly useful for treatment of Wilson Disease, but also for treatment of other conditions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {5}
}