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Title: Modular assemblies and systems for cell cultures and methods thereof

Abstract

The present invention relates to modular assemblies and systems for conducting cell analyses. In particular embodiments, an assembly has micron-scale fluidic structures, thereby minimizing sample use, and possesses a modular architecture that facilitates disassembly of the apparatus. Thus, one such modular assembly facilitates on-chip cell growth and on-chip assays; and then, as needed, the assembly can be disassembled to provide direct access to the cells that were incubated and treated within the chip. Methods of making and using such assemblies, as well as systems thereof, are further described herein.

Inventors:
; ;
Issue Date:
Research Org.:
Sandia National Lab. (SNL-CA), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1823893
Patent Number(s):
10988723
Application Number:
15/273,408
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/22/2016
Country of Publication:
United States
Language:
English

Citation Formats

Hatch, Anson, Abhyankar, Vinay, and Koh, Chung-Yan. Modular assemblies and systems for cell cultures and methods thereof. United States: N. p., 2021. Web.
Hatch, Anson, Abhyankar, Vinay, & Koh, Chung-Yan. Modular assemblies and systems for cell cultures and methods thereof. United States.
Hatch, Anson, Abhyankar, Vinay, and Koh, Chung-Yan. Tue . "Modular assemblies and systems for cell cultures and methods thereof". United States. https://www.osti.gov/servlets/purl/1823893.
@article{osti_1823893,
title = {Modular assemblies and systems for cell cultures and methods thereof},
author = {Hatch, Anson and Abhyankar, Vinay and Koh, Chung-Yan},
abstractNote = {The present invention relates to modular assemblies and systems for conducting cell analyses. In particular embodiments, an assembly has micron-scale fluidic structures, thereby minimizing sample use, and possesses a modular architecture that facilitates disassembly of the apparatus. Thus, one such modular assembly facilitates on-chip cell growth and on-chip assays; and then, as needed, the assembly can be disassembled to provide direct access to the cells that were incubated and treated within the chip. Methods of making and using such assemblies, as well as systems thereof, are further described herein.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {4}
}