Expanded pore particles and delivery methods thereof

Sasaki, Darryl Y.; Negrete, Oscar; Saada, Edwin A.; Fleig, Patrick Franz; Reed, Scott; Qiao, Eric L.

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A - human necessities
A01 - agriculture
A21 - baking
A22 - butchering
A23 - foods or foodstuffs
A24 - tobacco
A41 - wearing apparel
A42 - headwear
A43 - footwear
A44 - haberdashery
A45 - hand or travelling articles
A46 - brushware
A47 - furniture
A61 - medical or veterinary science
A62 - life-saving
A63 - sports
A99 - subject matter not otherwise provided for in this section
B - performing operations
B01 - physical or chemical processes or apparatus in general
B02 - crushing, pulverising, or disintegrating
B03 - separation of solid materials using liquids or using pneumatic tables or jigs
B04 - centrifugal apparatus or machines for carrying-out physical or chemical processes
B05 - spraying or atomising in general
B06 - generating or transmitting mechanical vibrations in general
B07 - separating solids from solids
B08 - cleaning
B09 - disposal of solid waste
B21 - mechanical metal-working without essentially removing material
B22 - casting
B23 - machine tools
B24 - grinding
B25 - hand tools
B26 - hand cutting tools
B27 - working or preserving wood or similar material
B28 - working cement, clay, or stone
B29 - working of plastics
B30 - presses
B31 - making articles of paper, cardboard or material worked in a manner analogous to paper
B32 - layered products
B33 - additive manufacturing technology
B41 - printing
B42 - bookbinding
B43 - writing or drawing implements
B44 - decorative arts
B60 - vehicles in general
B61 - railways
B62 - land vehicles for travelling otherwise than on rails
B63 - ships or other waterborne vessels
B64 - aircraft
B65 - conveying
B66 - hoisting
B67 - opening, closing {or cleaning} bottles, jars or similar containers
B68 - saddlery
B81 - microstructural technology
B82 - nanotechnology
B99 - subject matter not otherwise provided for in this section
C - chemistry
C01 - inorganic chemistry
C02 - treatment of water, waste water, sewage, or sludge
C03 - glass
C04 - cements
C05 - fertilisers
C06 - explosives
C07 - organic chemistry
C08 - organic macromolecular compounds
C09 - dyes
C10 - petroleum, gas or coke industries
C11 - animal or vegetable oils, fats, fatty substances or waxes
C12 - biochemistry
C13 - sugar industry
C14 - skins
C21 - metallurgy of iron
C22 - metallurgy
C23 - coating metallic material
C25 - electrolytic or electrophoretic processes
C30 - crystal growth
C40 - combinatorial technology
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D - textiles
D01 - natural or man-made threads or fibres
D02 - yarns
D03 - weaving
D04 - braiding
D05 - sewing
D06 - treatment of textiles or the like
D07 - ropes
D10 - indexing scheme associated with sublasses of section d, relating to textiles
D21 - paper-making
D99 - subject matter not otherwise provided for in this section
E - fixed constructions
E01 - construction of roads, railways, or bridges
E02 - hydraulic engineering
E03 - water supply
E04 - building
E05 - locks
E06 - doors, windows, shutters, or roller blinds in general
E21 - earth drilling
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F - mechanical engineering
F01 - machines or engines in general
F02 - combustion engines
F03 - machines or engines for liquids
F04 - positive - displacement machines for liquids
F05 - indexing schemes relating to engines or pumps in various subclasses of classes f01-f04
F15 - fluid-pressure actuators
F16 - engineering elements and units
F17 - storing or distributing gases or liquids
F21 - lighting
F22 - steam generation
F23 - combustion apparatus
F24 - heating
F25 - refrigeration or cooling
F26 - drying
F27 - furnaces
F28 - heat exchange in general
F41 - weapons
F42 - ammunition
F99 - subject matter not otherwise provided for in this section
G - physics
G01 - measuring
G02 - optics
G03 - photography
G04 - horology
G05 - controlling
G06 - computing
G07 - checking-devices
G08 - signalling
G09 - education
G10 - musical instruments
G11 - information storage
G12 - instrument details
G16 - information and communication technology [ict] specially adapted for specific application fields
G21 - nuclear physics
G99 - subject matter not otherwise provided for in this section
H - electricity
H01 - basic electric elements
H02 - generation
H03 - basic electronic circuitry
H04 - electric communication technique
H05 - electric techniques not otherwise provided for
H99 - subject matter not otherwise provided for in this section
Y - new / cross sectional technologies
Y02 - technologies or applications for mitigation or adaptation against climate change
Y04 - information or communication technologies having an impact on other technology areas
Y10 - technical subjects covered by former uspc

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Title: Expanded pore particles and delivery methods thereof

Abstract

The present invention relates to a construct including a porous core, a cargo, and a spacer disposed between the core and the cargo. In some examples, the construct further includes an outer layer composed of a lipid, a polymer, or a combination thereof. Methods of making and employing such constructs are also described herein.

Inventors:: Sasaki, Darryl Y.; Negrete, Oscar; Saada, Edwin A.; Fleig, Patrick Franz; Reed, Scott; Qiao, Eric L.

Issue Date:: 2021-03-02

Research Org.:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Org.:: USDOE National Nuclear Security Administration (NNSA)

OSTI Identifier:: 1805556

Patent Number(s):: 10933027

Application Number:: 16/141,725

Assignee:: National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K48/0075 - {characterised by an aspect of the delivery route, e.g. oral, subcutaneous}
A61K9/5115 - {Inorganic compounds}
A61K9/5123 - {Organic compounds, e.g. fats, sugars}
A61K9/5192 - {Processes}

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N15/11 - DNA or RNA fragments
C12N15/79 - Vectors or expression systems specially adapted for eukaryotic hosts
C12N15/90 - Stable introduction of foreign DNA into chromosome
C12N2310/20 - involving clustered regularly interspaced short palindromic repeats [CRISPRs]
C12N2320/32 - Special delivery means, e.g. tissue-specific

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S977/773 - Nanoparticle, i.e. structure having three dimensions of 100 nm or less
Y10S977/906 - Drug delivery

Show less

DOE Contract Number:: NA0003525

Resource Type:: Patent

Resource Relation:: Patent File Date: 09/25/2018

Country of Publication:: United States

Language:: English

Citation Formats


                    Sasaki, Darryl Y., Negrete, Oscar, Saada, Edwin A., Fleig, Patrick Franz, Reed, Scott, and Qiao, Eric L. Expanded pore particles and delivery methods thereof.  United States: N. p., 2021. 
        Web.

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                    Sasaki, Darryl Y., Negrete, Oscar, Saada, Edwin A., Fleig, Patrick Franz, Reed, Scott, & Qiao, Eric L. Expanded pore particles and delivery methods thereof.  United States.

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                    Sasaki, Darryl Y., Negrete, Oscar, Saada, Edwin A., Fleig, Patrick Franz, Reed, Scott, and Qiao, Eric L. Tue .  
        "Expanded pore particles and delivery methods thereof".  United States.  https://www.osti.gov/servlets/purl/1805556.

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@article{osti_1805556,

  title        = {Expanded pore particles and delivery methods thereof},

  author       = {Sasaki, Darryl Y. and Negrete, Oscar and Saada, Edwin A. and Fleig, Patrick Franz and Reed, Scott and Qiao, Eric L.},

  abstractNote = {The present invention relates to a construct including a porous core, a cargo, and a spacer disposed between the core and the cargo. In some examples, the construct further includes an outer layer composed of a lipid, a polymer, or a combination thereof. Methods of making and employing such constructs are also described herein.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2021},

  month        = {3}

}

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Similar Records

Title: Expanded pore particles and delivery methods thereof

Abstract

Citation Formats

Generation of Mesoporous Materials Using Multiphase Surfactant Systems patent-application, April 2018

CD 47 Containing Porous Nanoparticle Supported Lipid Bilayers (Protocells) Field of the Invention patent-application, April 2018

Delivery Platforms for the Domestication of Algae Plants patent-application, March 2016

Protocells and Their Use for Targeted Delivery of Multicomponent Cargos to Cancer Cells patent-application, June 2015

Protocells and their use for targeted delivery of multicomponent cargos to cancer cells patent, November 2016

Composition for Delivering Bioactive Material or Protein, and Use Thereof patent-application, June 2017

Carriers for Plasmid and RNP Delivery in the Treatment of Cancer and Other Disease States patent-application, February 2018

Protocells and their use for targeted delivery of multicomponent cargos to cancer cells patent, March 2015

Core and Surface Modification of Mesoporous Silica Nanoparticles to Achieve Cell Specific Targeting In Vivo. patent-application, October 2016

Torroidal Mesoporous Silica Nanoparticles (TMSNPS) and Related Protocells patent-application, November 2016

Toroidal mesoporous silica nanoparticles (TMSNPs) and related protocells patent, January 2018

Porous Nanoparticle-Supported Lipid Bilayers (Protocells) for Targeted Delivery Including Transdermal Delivery of Cargo and Methods Thereof patent-application, August 2017

Antibiotic Protocells and Related Pharmaceutical Formulations and Methods of Treatment patent-application, June 2017

Porous Nanoparticle Supported Lipid Nanostructures patent-application, October 2014

Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery and methods of using same patent, February 2017

Protocells and Their Use for Target Delivery of Multicomponent Cargos to Cancer Cells patent-application, November 2013

Nanobiocomposite Compositions and Methods patent-application, June 2018

Porous Nanoparticle-Supported Lipid Bilayers (Protocells) for Targeted Delivery and Methods of Using Same patent-application, April 2016

Porous Nanoparticle-Supported Lipid Bilayers (Photocells) for Targeted Delivery and Methods of Using Same patent-application, March 2014

Mesoporous Alum Nanoparticles as a Universal Platform for Antigen Adsorption, Presentation and Delivery patent-application, June 2016

Porous nanoparticle supported lipid bilayer nanostructures patent, May 2014

Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery and methods of using same patent, July 2018

CRLF-2 Binding Peptides, Protocells and Viral-Like Particles Useful in the Treatment of Cancer, Including Acute Lymphoblastic Leukemia (All) patent-application, January 2015

Porous Nanoparticle-Supported Lipid Bilayers (Protocells) for Targeted Delivery Including Transdermal Delivery of Cargo and Methods thereof patent-application, October 2015

Protocells for Plasmid and RNP Delivery in the Treatment of Cancer and Other Disease States patent-application, February 2018

Generation of Mesoporous Materials Using Multiphase Surfactant Systems
patent-application, April 2018

CD 47 Containing Porous Nanoparticle Supported Lipid Bilayers (Protocells) Field of the Invention
patent-application, April 2018

Delivery Platforms for the Domestication of Algae Plants
patent-application, March 2016

Protocells and Their Use for Targeted Delivery of Multicomponent Cargos to Cancer Cells
patent-application, June 2015

Protocells and their use for targeted delivery of multicomponent cargos to cancer cells
patent, November 2016

Composition for Delivering Bioactive Material or Protein, and Use Thereof
patent-application, June 2017

Carriers for Plasmid and RNP Delivery in the Treatment of Cancer and Other Disease States
patent-application, February 2018

Protocells and their use for targeted delivery of multicomponent cargos to cancer cells
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Core and Surface Modification of Mesoporous Silica Nanoparticles to Achieve Cell Specific Targeting In Vivo.
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Torroidal Mesoporous Silica Nanoparticles (TMSNPS) and Related Protocells
patent-application, November 2016

Toroidal mesoporous silica nanoparticles (TMSNPs) and related protocells
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Porous Nanoparticle-Supported Lipid Bilayers (Protocells) for Targeted Delivery Including Transdermal Delivery of Cargo and Methods Thereof
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