Targeted self-assembly of functionalized carbon nanotubes on tumors
Abstract
Provided herein is the two component self-assembly single wall nanotube system and the single wall nanotube construct that is the second component. The two component self-assembly single wall nanotube system has a morpholino oligonucleotide with a targeting moiety followed by a single wall nanotube construct with second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct.
- Inventors:
- Issue Date:
- Research Org.:
- Memorial Sloan-Kettering Cancer Center, New York, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1805418
- Patent Number(s):
- 10900037
- Application Number:
- 15/985,775
- Assignee:
- Sloan-Kettering Institute for Cancer Research Inc. (New York, NY)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- DOE Contract Number:
- SC0002456
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 05/22/2018
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 77 NANOSCIENCE AND NANOTECHNOLOGY
Citation Formats
Scheinberg, David A., McDevitt, Michael R., Villa, Carlos H., and Mulvey, Justin J. Targeted self-assembly of functionalized carbon nanotubes on tumors. United States: N. p., 2021.
Web.
Scheinberg, David A., McDevitt, Michael R., Villa, Carlos H., & Mulvey, Justin J. Targeted self-assembly of functionalized carbon nanotubes on tumors. United States.
Scheinberg, David A., McDevitt, Michael R., Villa, Carlos H., and Mulvey, Justin J. Tue .
"Targeted self-assembly of functionalized carbon nanotubes on tumors". United States. https://www.osti.gov/servlets/purl/1805418.
@article{osti_1805418,
title = {Targeted self-assembly of functionalized carbon nanotubes on tumors},
author = {Scheinberg, David A. and McDevitt, Michael R. and Villa, Carlos H. and Mulvey, Justin J.},
abstractNote = {Provided herein is the two component self-assembly single wall nanotube system and the single wall nanotube construct that is the second component. The two component self-assembly single wall nanotube system has a morpholino oligonucleotide with a targeting moiety followed by a single wall nanotube construct with second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {1}
}
Works referenced in this record:
Targeted self-assembly of functionalized carbon nanotubes on tumors
patent, May 2018
- Scheinberg, David A.; McDevitt, Michael R.; Villa, Carlos H.
- US Patent Document 9,976,137