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Title: Targeted self-assembly of functionalized carbon nanotubes on tumors

Abstract

Provided herein is the two component self-assembly single wall nanotube system and the single wall nanotube construct that is the second component. The two component self-assembly single wall nanotube system has a morpholino oligonucleotide with a targeting moiety followed by a single wall nanotube construct with second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct.

Inventors:
; ; ;
Issue Date:
Research Org.:
Memorial Sloan-Kettering Cancer Center, New York, NY (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1805418
Patent Number(s):
10900037
Application Number:
15/985,775
Assignee:
Sloan-Kettering Institute for Cancer Research Inc. (New York, NY)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
DOE Contract Number:  
SC0002456
Resource Type:
Patent
Resource Relation:
Patent File Date: 05/22/2018
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY

Citation Formats

Scheinberg, David A., McDevitt, Michael R., Villa, Carlos H., and Mulvey, Justin J. Targeted self-assembly of functionalized carbon nanotubes on tumors. United States: N. p., 2021. Web.
Scheinberg, David A., McDevitt, Michael R., Villa, Carlos H., & Mulvey, Justin J. Targeted self-assembly of functionalized carbon nanotubes on tumors. United States.
Scheinberg, David A., McDevitt, Michael R., Villa, Carlos H., and Mulvey, Justin J. Tue . "Targeted self-assembly of functionalized carbon nanotubes on tumors". United States. https://www.osti.gov/servlets/purl/1805418.
@article{osti_1805418,
title = {Targeted self-assembly of functionalized carbon nanotubes on tumors},
author = {Scheinberg, David A. and McDevitt, Michael R. and Villa, Carlos H. and Mulvey, Justin J.},
abstractNote = {Provided herein is the two component self-assembly single wall nanotube system and the single wall nanotube construct that is the second component. The two component self-assembly single wall nanotube system has a morpholino oligonucleotide with a targeting moiety followed by a single wall nanotube construct with second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {1}
}

Works referenced in this record:

Targeted self-assembly of functionalized carbon nanotubes on tumors
patent, May 2018