Fermentation process using yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol
Abstract
Yeast cells are genetically modified to disrupt a native metabolic pathway from dihydroxyacetone to glycerol. In certain aspects, the yeast cell is of the genera Kluyveromyces, Candida or Issatchenkia. In other aspects, the yeast cell is capable of producing at least one organic acid, such as lactate. The yeast cells produce significantly less glycerol than the wild-type strains, and usually produce greater yields of desired fermentation products. Yeast cells of the invention often grow well when cultivated, despite their curtailed glycerol production.
- Inventors:
- Issue Date:
- Research Org.:
- Cargill, Inc., Wayzata, MN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1805414
- Patent Number(s):
- 10899544
- Application Number:
- 15/941,274
- Assignee:
- Cargill, Incorporated (Wayzata, MN)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B65 - CONVEYING B65G - TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- FC36-03GO13145
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 03/30/2018
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Dundon, Catherine Asleson, Suominen, Pirrko, Aristidou, Aristos, Rush, Brian J., Koivuranta, Kari, Hause, Benjamin Matthew, McMullin, Thomas William, and Roberg-Perez, Kevin. Fermentation process using yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol. United States: N. p., 2021.
Web.
Dundon, Catherine Asleson, Suominen, Pirrko, Aristidou, Aristos, Rush, Brian J., Koivuranta, Kari, Hause, Benjamin Matthew, McMullin, Thomas William, & Roberg-Perez, Kevin. Fermentation process using yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol. United States.
Dundon, Catherine Asleson, Suominen, Pirrko, Aristidou, Aristos, Rush, Brian J., Koivuranta, Kari, Hause, Benjamin Matthew, McMullin, Thomas William, and Roberg-Perez, Kevin. Tue .
"Fermentation process using yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol". United States. https://www.osti.gov/servlets/purl/1805414.
@article{osti_1805414,
title = {Fermentation process using yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol},
author = {Dundon, Catherine Asleson and Suominen, Pirrko and Aristidou, Aristos and Rush, Brian J. and Koivuranta, Kari and Hause, Benjamin Matthew and McMullin, Thomas William and Roberg-Perez, Kevin},
abstractNote = {Yeast cells are genetically modified to disrupt a native metabolic pathway from dihydroxyacetone to glycerol. In certain aspects, the yeast cell is of the genera Kluyveromyces, Candida or Issatchenkia. In other aspects, the yeast cell is capable of producing at least one organic acid, such as lactate. The yeast cells produce significantly less glycerol than the wild-type strains, and usually produce greater yields of desired fermentation products. Yeast cells of the invention often grow well when cultivated, despite their curtailed glycerol production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {1}
}
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Works referenced in this record:
Method for producing lactic acid
patent-application, July 2007
- Yamaguchi, Ikuo; Saotome, Osamu; Kuromiya, Shigeru
- US Patent Application 10/592384; 20070161098