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Title: Non-coding RNAs linked to immortality and associated methods and compositions

Abstract

Aspects of the present disclosure include RNAs that confer a mortal phenotype and nucleic acids encoding same. Liposomes, recombinant cells, and pharmaceutical compositions that include the RNAs or nucleic acids encoding same are also provided. Further provided are methods involving quantifying MORT RNAs and/or determining the methylation status of the MORT promoter, as well as methods that employ the RNAs or nucleic acids encoding same.

Inventors:
; ; ;
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771741
Patent Number(s):
10870851
Application Number:
15/764,255
Assignee:
THThe Regents of the University of California (Oakland, CA); Arizona Board of Regents on Behalf of the University of Arizona (Tucson, AZ)
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 10/05/2016
Country of Publication:
United States
Language:
English

Citation Formats

Stampfer, Martha R., Garbe, James C., Vrba, Lukas, and Futscher, Bernard W. Non-coding RNAs linked to immortality and associated methods and compositions. United States: N. p., 2020. Web.
Stampfer, Martha R., Garbe, James C., Vrba, Lukas, & Futscher, Bernard W. Non-coding RNAs linked to immortality and associated methods and compositions. United States.
Stampfer, Martha R., Garbe, James C., Vrba, Lukas, and Futscher, Bernard W. Tue . "Non-coding RNAs linked to immortality and associated methods and compositions". United States. https://www.osti.gov/servlets/purl/1771741.
@article{osti_1771741,
title = {Non-coding RNAs linked to immortality and associated methods and compositions},
author = {Stampfer, Martha R. and Garbe, James C. and Vrba, Lukas and Futscher, Bernard W.},
abstractNote = {Aspects of the present disclosure include RNAs that confer a mortal phenotype and nucleic acids encoding same. Liposomes, recombinant cells, and pharmaceutical compositions that include the RNAs or nucleic acids encoding same are also provided. Further provided are methods involving quantifying MORT RNAs and/or determining the methylation status of the MORT promoter, as well as methods that employ the RNAs or nucleic acids encoding same.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {12}
}

Works referenced in this record:

Human cytosolic sulfotransferase database mining: identification of seven novel genes and pseudogenes
journal, December 2003


A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers
journal, October 2015