Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders
Abstract
Methods of promoting hypoxia or the hypoxia response for the treatment or prevention of mitochondrial dysfunction and oxidative stress disorders are described. Methods for screening for targets of mitochondrial dysfunction and oxidative stress disorders are also described.
- Inventors:
- Issue Date:
- Research Org.:
- The General Hospital Corp., Boston, MA (United States); Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1771657
- Patent Number(s):
- 10842812
- Application Number:
- 15/751,585
- Assignee:
- The General Hospital Corporation (Boston, MA); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, MA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- DOE Contract Number:
- FG02-97ER25308
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 08/12/2016
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Mootha, Vamsi K., Jain, Isha, Zapol, Warren M., and Zazzeron, Luca. Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders. United States: N. p., 2020.
Web.
Mootha, Vamsi K., Jain, Isha, Zapol, Warren M., & Zazzeron, Luca. Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders. United States.
Mootha, Vamsi K., Jain, Isha, Zapol, Warren M., and Zazzeron, Luca. Tue .
"Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders". United States. https://www.osti.gov/servlets/purl/1771657.
@article{osti_1771657,
title = {Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders},
author = {Mootha, Vamsi K. and Jain, Isha and Zapol, Warren M. and Zazzeron, Luca},
abstractNote = {Methods of promoting hypoxia or the hypoxia response for the treatment or prevention of mitochondrial dysfunction and oxidative stress disorders are described. Methods for screening for targets of mitochondrial dysfunction and oxidative stress disorders are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {11}
}
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