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Title: Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders

Abstract

Methods of promoting hypoxia or the hypoxia response for the treatment or prevention of mitochondrial dysfunction and oxidative stress disorders are described. Methods for screening for targets of mitochondrial dysfunction and oxidative stress disorders are also described.

Inventors:
; ; ;
Issue Date:
Research Org.:
The General Hospital Corp., Boston, MA (United States); Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771657
Patent Number(s):
10842812
Application Number:
15/751,585
Assignee:
The General Hospital Corporation (Boston, MA); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, MA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
FG02-97ER25308
Resource Type:
Patent
Resource Relation:
Patent File Date: 08/12/2016
Country of Publication:
United States
Language:
English

Citation Formats

Mootha, Vamsi K., Jain, Isha, Zapol, Warren M., and Zazzeron, Luca. Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders. United States: N. p., 2020. Web.
Mootha, Vamsi K., Jain, Isha, Zapol, Warren M., & Zazzeron, Luca. Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders. United States.
Mootha, Vamsi K., Jain, Isha, Zapol, Warren M., and Zazzeron, Luca. Tue . "Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders". United States. https://www.osti.gov/servlets/purl/1771657.
@article{osti_1771657,
title = {Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders},
author = {Mootha, Vamsi K. and Jain, Isha and Zapol, Warren M. and Zazzeron, Luca},
abstractNote = {Methods of promoting hypoxia or the hypoxia response for the treatment or prevention of mitochondrial dysfunction and oxidative stress disorders are described. Methods for screening for targets of mitochondrial dysfunction and oxidative stress disorders are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {11}
}

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