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Title: Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds


Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).

Issue Date:
Research Org.:
North Carolina State Univ., Raleigh, NC (United States)
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OSTI Identifier:
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North Carolina State University (Raleigh, NC)
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Patent File Date: 11/27/2017
Country of Publication:
United States

Citation Formats

Lindsey, Jonathan S., and Zhang, Shaofei. Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds. United States: N. p., 2020. Web.
Lindsey, Jonathan S., & Zhang, Shaofei. Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds. United States.
Lindsey, Jonathan S., and Zhang, Shaofei. Tue . "Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds". United States.
title = {Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds},
author = {Lindsey, Jonathan S. and Zhang, Shaofei},
abstractNote = {Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {11}

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