Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds

Lindsey, Jonathan S.; Zhang, Shaofei

Title: Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds

Abstract

Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).

Inventors:: Lindsey, Jonathan S.; Zhang, Shaofei

Issue Date:: 2020-11-17

Research Org.:: North Carolina State University, Raleigh, NC (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1771632

Patent Number(s):: 10836774

Application Number:: 16/464,728

Assignee:: North Carolina State University (Raleigh, NC)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K31/409 - having four such rings, e.g. porphine derivatives, bilirubin, biliverdine

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P35/00 - Antineoplastic agents

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
C07D487/22 - in which the condensed system contains four or more hetero rings

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DOE Contract Number:: FG02-05ER15661

Resource Type:: Patent

Resource Relation:: Patent File Date: 11/27/2017

Country of Publication:: United States

Language:: English

Citation Formats


                    Lindsey, Jonathan S., and Zhang, Shaofei. Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds.  United States: N. p., 2020. 
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                    Lindsey, Jonathan S., & Zhang, Shaofei. Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds.  United States.

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                    Lindsey, Jonathan S., and Zhang, Shaofei. Tue .  
        "Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds".  United States.  https://www.osti.gov/servlets/purl/1771632.

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@article{osti_1771632,

  title        = {Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds},

  author       = {Lindsey, Jonathan S. and Zhang, Shaofei},

  abstractNote = {Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2020},

  month        = {11}

}

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Works referenced in this record:

Dialkylated glycol compositions and medicament preparations containing same
patent, May 1976

Thompson, Geoffrey F.
US Patent Document RE28,819
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/RE28819

Tris(3-mercaptopropyl)- N -glycylaminomethane as a New Linker to Bridge Antibody with Metal Particles for Biological Cell Separations
journal, June 2000

Siiman, Olavi; Burshteyn, Alexander; Maples, John A.
Bioconjugate Chemistry, Vol. 11, Issue 4
https://doi.org/10.1021/bc990176u

Photovoltaic cell interconnection
patent, March 2004

Gaudiana, Russell; Li, Lian
US Patent Document 6,706,963
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6706963

Catalytic Enantioselective Pyrrole Alkylations of α,β-Unsaturated 2-Acyl Imidazoles
journal, May 2006

Evans, David A.; Fandrick, Keith R.
Organic Letters, Vol. 8, Issue 11
https://doi.org/10.1021/ol060576e

Epimerization of Chlorophyll Derivatives. V. Effects of the Central Magnesium and Ring Substituents on the Epimerization of Chlorophyll Derivatives
journal, November 1992

Mazaki, Hitoshi; Watanabe, Tadashi; Takahashi, Terumi
Bulletin of the Chemical Society of Japan, Vol. 65, Issue 11
https://doi.org/10.1246/bcsj.65.3080

Photovoltaic fibers
patent, July 2005

Chittibabu, Kethinni; Eckert, Robert D.; Gaudiana, Russell
US Patent Document 6,913,713
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6913713

High-density non-volatile memory devices incorporating sandwich coordination compounds
patent, April 2001

Lindsey, Jonathan S.
US Patent Document 6,212,093
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6212093

Novel bicycloannulation via tandem vinylation and intramolecular Diels-Alder reaction of five-membered heterocycles: a new approach to construction of psoralen and azapsoralen
journal, October 1984

Hayakawa, Kenji; Yodo, Mitsuaki; Ohsuki, Satoru
Journal of the American Chemical Society, Vol. 106, Issue 22
https://doi.org/10.1021/ja00334a044

Syntheses, characterization, and structural chemistry of biladien-ac-10-one and -bc-5-one metal complexes with 4N or (3N + O) co-ordination
journal, January 1996

Khoury, Richard G.; Senge, Mathias O.; Colchester, John E.
Journal of the Chemical Society, Dalton Transactions, Issue 20
https://doi.org/10.1039/dt9960003937

Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
patent, October 1997

Ekwuribe, Nnochiri
US Patent Document 5,681,811
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5681811

Preparation of bispecific antibodies by chemical recombination of monoclonal immunoglobulin G1 fragments
journal, July 1985

Brennan, M.; Davison, P.; Paulus, H.
Science, Vol. 229, Issue 4708
https://doi.org/10.1126/science.3925553

High density non-volatile memory device
patent, April 2002

Bocian, David F.; Kuhr, Werner G.; Lindsey, Jonathan S.
US Patent Document 6,381,169
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6381169

Long-Range Electron Transfer across Molecule−Nanocrystalline Semiconductor Interfaces Using Tripodal Sensitizers
journal, July 2002

Galoppini, Elena; Guo, Wenzhuo; Zhang, Wei
Journal of the American Chemical Society, Vol. 124, Issue 26
https://doi.org/10.1021/ja025840n

The facile and efficient Michael addition of indoles and pyrrole to α,β-unsaturated electron-deficient compounds catalyzed by aluminium dodecyl sulfate trihydrate [Al(DS) ₃ ]·3H ₂ O in water
journal, January 2005

Firouzabadi, Habib; Iranpoor, Nasser; Nowrouzi, Farhad
Chem. Commun., Issue 6
https://doi.org/10.1039/B412653J

Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
patent, February 2000

D'Angelo, Joseph P.; Schur, Henry
US Patent Document 6,024,975
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6024975

Synthesis of tripodal [2]rotaxanes: high concentration principleElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b2/b209836a/
journal, December 2002

Nikitin, Kirill; Long, Brenda; Fitzmaurice, Donald
Chemical Communications, Issue 2
https://doi.org/10.1039/b209836a

Photovoltaic cell
patent, August 2005

Shaheen, Sean; Brabec, Christoph; Fromherz, Thomas
US Patent Document 6,933,436
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6933436

Swallowtail motifs for imparting water solubility to porphyrinic compounds
patent, September 2013

Borbas, K. Eszter; Lindsey, Jonathan S.
US Patent Document 8,530,459
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8530459

CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
patent, April 1989

Primus, Frederick J.; Goldenberg, Milton D.
US Patent Document 4,818,709
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4818709

Packaged pharmaceutical product
patent, October 1991

Carter, Douglas V.
US Patent Document 5,052,558
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5052558

Conjugate addition of pyrroles to α,β-unsaturated ketones using copper bromide as a catalyst
journal, October 2006

Kusurkar, Radhika S.; Nayak, Sandip K.; Chavan, Neelam L.
Tetrahedron Letters, Vol. 47, Issue 41
https://doi.org/10.1016/j.tetlet.2006.08.030

Method of packaging and sterilizing a pharmaceutical product
patent, July 1991

Carter, Douglas V.
US Patent Document 5,033,252
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5033252

Pulseless liquid supply system for flow cytometry
patent, June 1999

North, Jr., Howard L.
US Patent Document 5,915,925
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5915925

The Pigment Complement of the Photosynthetic Reaction Center Isolated from Rhodospirillum rubrum
journal, October 1974

van der Rest, Michel; Gingras, Gabriel
Journal of Biological Chemistry, Vol. 249, Issue 20
https://doi.org/10.1016/S0021-9258(19)42177-7

Highly Enantioselective Synthesis of β-Heteroaryl-Substituted Dihydrochalcones Through Friedel-Crafts Alkylation of Indoles and Pyrrole
journal, February 2010

Wang, Wentao; Liu, Xiaohua; Cao, Weidi
Chemistry - A European Journal, Vol. 16, Issue 5
https://doi.org/10.1002/chem.200902355

Selective Michael addition of pyrrole to conjugated alkenes catalyzed by Cr3+-Catsan and ZnCl2
journal, August 2006

Zhang, Chuan-Xin; Wang, Yi-Qiang; Duan, Yong-Sheng
Catalysis Communications, Vol. 7, Issue 8
https://doi.org/10.1016/j.catcom.2006.01.011

Cyclodextrin polymers for carrying and releasing drugs
patent, April 2000

Kosak, Kenneth M.
US Patent Document 6,048,736
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6048736

Tumor localization and therapy with labeled anti-CEA antibody
patent, September 1982

Goldenberg, Milton D.
US Patent Document 4,348,376
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4348376

Method for diagnostically imaging lesions in the brain inside a blood-brain barrier
patent, October 1991

Neuwelt, Edward A.
US Patent Document 5,059,415
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5059415

Taste-masked microcapsule compositions and methods of manufacture
patent, October 2000

Friend, David R.; Ng, Steve Y.; Sarabia, Rafael E.
US Patent Document 6,139,865
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6139865

Method and apparatus for flow cytometry
patent, July 2003

Malachowski, George C.
US Patent Document 6,589,792
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6589792

Localization of tumors by radiolabelled antibodies
patent, December 1975

Hansen, Hans John; Primus, Frederick James
US Patent Document 3,927,193
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/3927193

Microwave-Assisted Addition of Pyrroles to Electron-Deficient Olefins: A Rapid Entry to C -Alkyl Pyrroles
journal, January 2005

Zhan, Zhuang-Ping; Yang, Wen-Zhen; Yang, Rui-Feng
Synlett, Issue 16
https://doi.org/10.1055/s-2005-872688

Pyrroles and related compounds. Part XXX. Cyclisation of porphyrin β-keto-esters to phaeoporphyrins
journal, January 1974

Kenner, George W.; McCombie, Stuart W.; Smith, Kevin M.
J. Chem. Soc., Perkin Trans. 1, Issue 0
https://doi.org/10.1039/P19740000527

Monoclonal antibodies against microorganisms
journal, October 1984

Polin, R. A.
European Journal of Clinical Microbiology, Vol. 3, Issue 5
https://doi.org/10.1007/BF02017358

De Novo Synthesis of Bacteriochlorins
patent-application, August 2006

Kim, Han-Je; Lindsey, Jonathan S.
US Patent Application 11/357833; 20060194960
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20060194960

The Nazarov Cyclization: A Valuable Method to Synthesize Fully Substituted Carbon Stereocenters: Nazarov Cyclization
journal, September 2014

Wenz, Donald R.; Read de Alaniz, Javier
European Journal of Organic Chemistry, Vol. 2015, Issue 1
https://doi.org/10.1002/ejoc.201402825

Non-immunogenic polypeptides
patent, December 1979

Davis, Frank F.; Van Es, Theodorus; Palczuk, Nicholas C.
US Patent Document 4,179,337
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4179337

Chlorophyll breakdown in higher plants
journal, August 2011

Hörtensteiner, Stefan; Kräutler, Bernhard
Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1807, Issue 8
https://doi.org/10.1016/j.bbabio.2010.12.007

The Combination Treatment of Ultrasound and Antitumor Drugs on Yoshida Sarcoma [吉田肉腫に対する抗腫瘍薬と超音波の併用治療]
journal, January 1987

Yumita, Nagahiko; Okumura, Akihiko; Nishigaki, Ryuichiro
Thermal Medicine(Japanese Journal of Hyperthermic Oncology), Vol. 3, Issue 2
https://doi.org/10.3191/thermalmedicine.3.175

Drug mitochondrial targeting agents
patent, November 2001

Steliou, Kosta
US Patent Document 6,316,652
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6316652

Temperature controlling device for aerosol drug delivery
patent, October 2000

Schuster, Jeffrey A.; Flaim, Christopher
US Patent Document 6,131,570
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6131570

Synthesis and Structure of Tolyporphin A O,O -Diacetate
journal, October 1999

Wang, Wengui; Kishi, Yoshito
Organic Letters, Vol. 1, Issue 7
https://doi.org/10.1021/ol9902374

A General Method for the Catalytic Nazarov Cyclization of Heteroaromatic Compounds
journal, October 2006

Malona, John A.; Colbourne, Jessica M.; Frontier, Alison J.
Organic Letters, Vol. 8, Issue 24
https://doi.org/10.1021/ol062403v

Acetal stabilized prostaglandin compositions
patent, November 1982

Yu, Cheng-Der Tony
US Patent Document 4,358,603
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4358603

Structural characteristics that make chlorophylls green: interplay of hydrocarbon skeleton and substituents
journal, January 2011

Mass, Olga; Taniguchi, Masahiko; Ptaszek, Marcin
New J. Chem., Vol. 35, Issue 1
https://doi.org/10.1039/C0NJ00652A

Pyrroles and related compounds. Part XXVIII. β-Keto-esters in the porphyrin series
journal, January 1974

Cox, Michael T.; Howarth, T. Trefor; Jackson, Anthony H.
J. Chem. Soc., Perkin Trans. 1, Issue 0
https://doi.org/10.1039/P19740000512

Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier.
journal, June 1990

Rakestraw, S. L.; Tompkins, R. G.; Yarmush, M. L.
Proceedings of the National Academy of Sciences, Vol. 87, Issue 11
https://doi.org/10.1073/pnas.87.11.4217

Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
patent, May 2000

Chen, Hongming; Langer, Robert S.
US Patent Document 6,060,082
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6060082

Michael Reactions of α-Unsubstituted Trisubstituted 1 H -Pyrroles
journal, January 1991

Lüönd, Rainer; Neier, Reinhard
Helvetica Chimica Acta, Vol. 74, Issue 1
https://doi.org/10.1002/hlca.19910740111

Single polypeptide chain binding molecules
patent, August 1990

Ladner, Robert Charles; Bird, Robert; Hardman, Karl D.
US Patent Document 4,946,778
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4946778

Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles
patent, November 1986

Goldenberg, Milton D.
US Patent Document 4,624,846
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4624846

Electrophoretic cuff apparatus drug delivery system
patent, November 1999

Ostrow, Alvin S.
US Patent Document 5,983,134
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5983134

The total synthesis of chlorophyll a
journal, January 1990

Woodward, Robert Burns; Ayer, William A.; Beaton, John M.
Tetrahedron, Vol. 46, Issue 22
https://doi.org/10.1016/0040-4020(90)80003-Z

Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
patent, November 1999

Venkateshwaran, Srinivasan; Fikstad, David; Ebert, Charles D.
US Patent Document 5,985,317
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5985317

Recombinant monoclonal antibodies
patent, October 1984

Reading, Christopher
US Patent Document 4,474,893
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4474893

Serendipitous synthetic entrée to tetradehydro analogues of cobalamins
journal, January 2013

Deans, Richard M.; Mass, Olga; Diers, James R.
New Journal of Chemistry, Vol. 37, Issue 12
https://doi.org/10.1039/c3nj00574g

Recent advances in sonodynamic approach to cancer therapy
journal, November 1996

Umemura, S.; Kawabata, K.; Sasaki, K.
Ultrasonics Sonochemistry, Vol. 3, Issue 3
https://doi.org/10.1016/S1350-4177(96)00024-7

Facile synthesis of a B,D-tetradehydrocorrin and rearrangement to bacteriochlorins
journal, January 2011

Aravindu, Kunche; Krayer, Michael; Kim, Han-Je
New Journal of Chemistry, Vol. 35, Issue 7
https://doi.org/10.1039/c1nj20027e

Production of target-specific effector cells using hetero-cross-linked aggregates containing anti-target cell and anti-Fc gamma receptor antibodies.
journal, December 1984

Karpovsky, B.; Titus, J. A.; Stephany, D. A.
Journal of Experimental Medicine, Vol. 160, Issue 6
https://doi.org/10.1084/jem.160.6.1686

Targeted polymerized liposomes for improved drug delivery
patent, December 1999

Langer, Robert S.; Chen, Hongming
US Patent Document 6,004,534
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6004534

One pot direct synthesis of β-ketoesters via carbonylation of aryl halides using cobalt carbonyl
journal, June 2014

Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, Vol. 55, Issue 25
https://doi.org/10.1016/j.tetlet.2014.04.087

Charged lipids and uses for the same
patent, September 2000

Unger, Evan C.
US Patent Document 6,120,751
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6120751

Metal Triflates-Catalyzed Conjugate Addition of Homochiral Pyrroles to α,β-Unsaturated Esters
journal, January 2004

Ünaleroglu, Canan; Temelli, Baris; Demir, Ayhan S.
Synthesis, Vol. 2004, Issue 15
https://doi.org/10.1055/s-2004-831195

De novo synthesis and photophysical characterization of annulated bacteriochlorins. Mimicking and extending the properties of bacteriochlorophylls
journal, January 2011

Krayer, Michael; Yang, Eunkyung; Diers, James R.
New Journal of Chemistry, Vol. 35, Issue 3, p. 587-601
https://doi.org/10.1039/c0nj00771d

A New Route for Installing the Isocyclic Ring on Chlorins Yielding 13 ¹ -Oxophorbines
journal, September 2006

Laha, Joydev K.; Muthiah, Chinnasamy; Taniguchi, Masahiko
The Journal of Organic Chemistry, Vol. 71, Issue 18
https://doi.org/10.1021/jo0608265

Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
patent, May 1982

Goldenberg, Milton D.
US Patent Document 4,331,647
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4331647

New Strategies in Organic Catalysis: The First Enantioselective Organocatalytic Friedel−Crafts Alkylation
journal, May 2001

Paras, Nick A.; MacMillan, David W. C.
Journal of the American Chemical Society, Vol. 123, Issue 18
https://doi.org/10.1021/ja015717g

Transdermal drug patch with attached pocket for controlled heating device
patent, July 2001

Stanley, Theodore H.; Hull, Wade; Rigby, Larry
US Patent Document 6,261,595
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6261595

Preparation of α- and β-substituted alanine derivatives by α-amidoalkylation or Michael addition reactions under heterogeneous catalysis assisted by microwave irradiation
journal, June 2001

de la Hoz, Antonio; Dı́az-Ortiz, Angel; Victoria Gómez, Marı́a
Tetrahedron, Vol. 57, Issue 25
https://doi.org/10.1016/S0040-4020(01)00461-6

Gadolinium triflate catalyzed alkylation of pyrroles: efficient synthesis of 3-oxo-2,3-dihydro-1H-pyrrolizine derivatives
journal, June 2007

Unaleroglu, Canan; Yazici, Arife
Tetrahedron, Vol. 63, Issue 25
https://doi.org/10.1016/j.tet.2007.04.018

Enzyme Amplification Assay
patent, June 1974

Rubenstein, Kenneth E.; Ullman, Edwin F.
US Patent Document 3,817,837
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/3817837

Tetrapartate prodrugs
patent, April 2004

Greenwald, Richard B.; Zhao, Hong
US Patent Document 6,720,306
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6720306

Nomenclature of tetrapyrroles (Recommendations 1986)
journal, January 1987

Moss, G. P.
Pure and Applied Chemistry, Vol. 59, Issue 6
https://doi.org/10.1351/pac198759060779

Fluorinated Photosensitizers Related to Chlorins and Bacteriochlorins for Photodynamic Therapy
patent-application, March 2004

Pandey, Ravindra K.; Potter, William R.; Dougherty, Thomas J.
US Patent Application 10/607922; 20040044197
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20040044197

De Novo Synthesis of Gem-Dialkyl Chlorophyll Analogues for Probing and Emulating Our Green World
journal, June 2015

Lindsey, Jonathan S.
Chemical Reviews, Vol. 115, Issue 13
https://doi.org/10.1021/acs.chemrev.5b00065

Directionally Aligned Helical Peptides on Surfaces
journal, July 1993

Whitesell, J. K.; Chang, H. K.
Science, Vol. 261, Issue 5117
https://doi.org/10.1126/science.261.5117.73

The Total Synthesis of Chlorophyll
journal, July 1960

Woodward, R. B.; Ayer, W. A.; Beaton, J. M.
Journal of the American Chemical Society, Vol. 82, Issue 14
https://doi.org/10.1021/ja01499a093

Proton relaxation enhancement of albumin, immunoglobulin g, and fibrinogen labeled with gd-dtpa
journal, January 1990

Paajanen, Hannu; Reisto, Timo; Hemmilä, Ilkka
Magnetic Resonance in Medicine, Vol. 13, Issue 1
https://doi.org/10.1002/mrm.1910130106

Flow cytometry for high throughput screening
patent, May 2005

Sklar, Larry A.; Edwards, Bruce S.; Kuckuck, Frederick
US Patent Document 6,890,487
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6890487

Cinchona-based primary amine-catalyzed enantioselective aza-Michael reactions of pyrroles with α,β-unsaturated aldehydes
journal, October 2014

Lee, Su-Jeong; Ahn, Jun-Gi; Cho, Chang-Woo
Tetrahedron: Asymmetry, Vol. 25, Issue 20-21
https://doi.org/10.1016/j.tetasy.2014.09.002

Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
patent, June 1998

Gurewich, Victor
US Patent Document 5,759,542
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5759542

Enantioselective Enolate Protonations: Friedel-Crafts Reactions with α-Substituted Acrylates
journal, December 2008

Sibi, Mukund P.; Coulomb, Julien; Stanley, Levi M.
Angewandte Chemie International Edition, Vol. 47, Issue 51
https://doi.org/10.1002/anie.200804221

A Highly Reactive Dicationic Iridium(III) Catalyst for the Polarized Nazarov Cyclization Reaction
journal, March 2010

Vaidya, Tulaza; Atesin, Abdurrahman C.; Herrick, Ildiko R.
Angewandte Chemie International Edition, Vol. 49, Issue 19
https://doi.org/10.1002/anie.201000100

Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water
journal, January 2006

Azizi, Najmedin; Arynasab, Fezzeh; Saidi, Mohammad R.
Org. Biomol. Chem., Vol. 4, Issue 23
https://doi.org/10.1039/B610263H

Sonodynamically induced antitumor effect of gallium-porphyrin complex by focused ultrasound on experimental kidney tumor
journal, January 1997

Yumita, Nagahiko; Sasaki, Kazuaki; Umemura, Shin-ichiro
Cancer Letters, Vol. 112, Issue 1
https://doi.org/10.1016/S0304-3835(96)04548-X

Track soundproofing arrangement
patent, July 2001

Neumann, Bernhard
US Patent Document 6,253,872
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6253872

Iron(III) Salt-Catalyzed Nazarov Cyclization/Michael Addition of Pyrrole Derivatives
journal, December 2008

Fujiwara, Masamune; Kawatsura, Motoi; Hayase, Shuichi
Advanced Synthesis & Catalysis, Vol. 351, Issue 1-2
https://doi.org/10.1002/adsc.200800702

Composition and method for delivery of biologically-active factors
patent, August 2001

Tamarkin, Lawrence; Paciotti, Guilio F.
US Patent Document 6,274,552
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6274552

Addition of pyrroles to electron deficient olefins employing InCl3
journal, November 2001

Yadav, J. S.; Abraham, Sunny; Subba Reddy, B. V.
Tetrahedron Letters, Vol. 42, Issue 45
https://doi.org/10.1016/S0040-4039(01)01697-5

De Novo Synthesis of Stable Tetrahydroporphyrinic Macrocycles: Bacteriochlorins and a Tetradehydrocorrin
journal, July 2005

Kim, Han-Je; Lindsey, Jonathan S.
The Journal of Organic Chemistry, Vol. 70, Issue 14
https://doi.org/10.1021/jo050467y

Device for local drug delivery and methods for using the same
patent, January 1998

Hanson, Stephen R.; Scott, Neal; King, III, Spencer B.
US Patent Document 5,709,874
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5709874

Porphyrin β-keto-esters and their cyclisation to phaeoporphyrins
journal, January 1972

Kenner, G. W.; McCombie, S. W.; Smith, K. M.
J. Chem. Soc., Chem. Commun., Vol. 0, Issue 14
https://doi.org/10.1039/C39720000844

Multistate triple-decker dyads in three distinct architectures for information storage applications
patent, April 2004

Lindsey, Jonathan S.; Bocian, David F.; Schweikart, Karl-Heinz
US Patent Document 6,728,129
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6728129

Device and method for non-occlusive localized drug delivery
patent, November 1999

Hanson, Stephen R.; Scott, Neal; King, III, Spencer B.
US Patent Document 5,985,307
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5985307

Immunoglobulin half-molecules and process for producing hybrid antibodies
patent, October 1984

Auditore-Hargreaves, Karen
US Patent Document 4,479,895
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4479895

Tandem reactions of Friedel–Crafts/aldehyde cyclotrimerization catalyzed by an organotungsten Lewis acid
journal, February 2002

Wang, Hsing-Shiun; Yu, Shuchun Joyce
Tetrahedron Letters, Vol. 43, Issue 6
https://doi.org/10.1016/S0040-4039(01)02323-1

Synthesis of porphyrins. Deoxophylloerythroetioporphyrin
journal, November 1968

Flaugh, Michael E.; Rapoport, Henry
Journal of the American Chemical Society, Vol. 90, Issue 24
https://doi.org/10.1021/ja01026a076

1,1,1-Trifluoro-2-penten-4-one as a building block of trifluoromethyl-substituted compounds
journal, June 1986

Ogoshi, Hisanobu; Mizushima, Hiromoto; Toi, Hiroo
The Journal of Organic Chemistry, Vol. 51, Issue 12
https://doi.org/10.1021/jo00362a034

Refined syntheses of hydrodipyrrin precursors to chlorin and bacteriochlorin building blocks
journal, October 2009

Krayer, Michael; Balasubramanian, Thiagarajan; Ruzié, Christian
Journal of Porphyrins and Phthalocyanines, Vol. 13, Issue 10
https://doi.org/10.1142/S1088424609001406

Drug releasing surgical implant or dressing material
patent, October 1999

Haynes, Duncan H.; Bodeker, Ben H.; Kline, Mark D.
US Patent Document 5,972,366
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5972366

Polymer battery for internal light device
patent, August 2001

Chen, James C.; Brown, David J.; Wilkerson, Brian D.
US Patent Document 6,273,904
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6273904

A trans-AB-Bacteriochlorin Building Block
journal, November 2011

Mass, Olga; Lindsey, Jonathan S.
The Journal of Organic Chemistry, Vol. 76, Issue 22, p. 9478-9487
https://doi.org/10.1021/jo201967k

Drug-Delivery Device with Stretched, Rate-Controlling Membrane
patent, January 1973

Higuchi, Takeru; Leeper, Harold M.
US Patent Document 3,710,795
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/3710795

Propylene glycol diester solutions of PGE-type compounds
patent, October 1983

Yu, Cheng-Der Tony
US Patent Document 4,409,239
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4409239

High density non-volatile memory device incorporating thiol-derivatized porphyrins
patent, March 2001

Gryko, Daniel T.; Clausen, Peter Christian; Roth, Kristian
US Patent Document 6,208,553
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6208553

Tightly coupled porphyrin macrocycles for molecular memory storage
patent, November 2001

Gryko, Daniel T.; Clausen, Peter Christian; Bocian, David F.
US Patent Document 6,324,091
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6324091

Regioselective Bromination Tactics in the de Novo Synthesis of Chlorophyll b Analogues
journal, May 2009

Muthiah, Chinnasamy; Lahaye, Dorothée; Taniguchi, Masahiko
The Journal of Organic Chemistry, Vol. 74, Issue 9
https://doi.org/10.1021/jo9002954

Synthesis and michael reaction of 3,4-dimethylpyrrole
journal, October 1976

Cheng, D. O.; Bowman, T. L.; Legoff, E.
Journal of Heterocyclic Chemistry, Vol. 13, Issue 5
https://doi.org/10.1002/jhet.5570130549

Iron Salt-cataltzed Multipoint Alkylation of Pyrrole with Vinyl Ketones
journal, July 2008

Kawatsura, Motoi; Fujiwara, Masamune; Uehara, Hiroyuki
Chemistry Letters, Vol. 37, Issue 7
https://doi.org/10.1246/cl.2008.794

Synthetic bacteriochlorins with integral spiro-piperidine motifs
journal, January 2013

Reddy, Kanumuri Ramesh; Lubian, Elisa; Pavan, M. Phani
New Journal of Chemistry, Vol. 37, Issue 4
https://doi.org/10.1039/c3nj41161c

Multifunctional Bacteriochlorins from Selective Palladium-Coupling Reactions
journal, July 2012

Yu, Zhanqian; Ptaszek, Marcin
Organic Letters, Vol. 14, Issue 14
https://doi.org/10.1021/ol3015545

Chemical compounds
patent, December 1982

Cook, Peter B.; Hunt, John H.
US Patent Document 4,364,923
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4364923

Tissue-specific and pathogen-specific toxic agents and ribozymes
patent, August 2001

Norris, James; Clawson, Gary; Westwater, Caroline
US Patent Document 6,271,359
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6271359

An Efficient Synthetic Route for Pyrrolizinone Synthesis through Functionalized C-Alkylpyrroles
journal, August 2009

Unaleroglu, Canan; Tasgin, Dilek; Aytac, Sertan
Synthesis, Vol. 2009, Issue 19
https://doi.org/10.1055/s-0029-1216951

Child resistant package assembly for dispensing pharmaceutical medications
patent, June 1994

Kalvelage, John D.
US Patent Document 5,323,907
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5323907

Covalent microparticle-drug conjugates for biological targeting
patent, November 1998

Yatvin, Milton B.; Stowell, Michael H. B.; Gallicchio, Vincent S.
US Patent Document 5,840,674
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5840674

Facile Convergent Route to Molecular Caltrops
journal, February 1999

Yao, Yuxing; Tour, James M.
The Journal of Organic Chemistry, Vol. 64, Issue 6
https://doi.org/10.1021/jo982085g

Iodine-catalyzed efficient conjugate addition of pyrroles to α,β-unsaturated ketones
journal, April 2007

Das, Biswanath; Chowdhury, Nikhil; Damodar, Kongara
Tetrahedron Letters, Vol. 48, Issue 16
https://doi.org/10.1016/j.tetlet.2007.02.094

Colon targeted delivery system
patent, March 2000

Shah, Navnit H.; Railkar, Aruna; Phuapradit, Wantanee
US Patent Document 6,039,975
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6039975

Passive immunization of mice against Schistosoma mansoni with an IgM monoclonal antibody
journal, February 1982

Smith, M. A.; Clegg, J. A.; Snary, D.
Parasitology, Vol. 84, Issue 1
https://doi.org/10.1017/S0031182000051684

Recent advances in the synthesis of porphyrins with five-membered exocyclic rings
journal, March 1993

Lash, Timothy D.; Quizon-Colquitt, Desiree M.; Shiner, Craig M.
Energy & Fuels, Vol. 7, Issue 2
https://doi.org/10.1021/ef00038a002

Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
patent, November 1982

Goldenberg, Milton D.
US Patent Document 4,361,544
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4361544

Compounds having affinity for the granulocyte-colony stimulating factor receptor (G-CSFR) and associated uses
patent, April 2004

Cwirla, Steven E.; Balu, Palani; Duffin, David J.
US Patent Document 6,716,811
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6716811

Hybrid hybridomas and the production of bi-specific monoclonal antibodies
journal, October 1984

Milstein, C.; Cuello, A. C.
Immunology Today, Vol. 5, Issue 10
https://doi.org/10.1016/0167-5699(84)90155-5

Multipathway electronically-controlled drug delivery system
patent, January 1999

Jacobsen, Stephen C.; Wyatt, Roland; Peterson, Stephen C.
US Patent Document 5,860,957
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5860957

Apparatus and method for using an intracutaneous microneedle array
patent, July 2001

Yuzhakov, Vadim Vladimirovich; Sherman, Faiz Feisal; Owens, Grover
US Patent Document 6,256,533
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6256533

Carbonate diester solutions of PGE-type compounds
patent, May 1982

Yu, Cheng-Der Tony; Bruenner, Ursula
US Patent Document 4,328,245
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4328245

Low temperature interconnection of nanoparticles
patent, February 2005

Chittibabu, Kethinni; Gaudiana, Russell
US Patent Document 6,858,158
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6858158

Isolation and partial characterization of the tegumental outer membrane of adult Schistosoma mansoni
journal, August 1981

Simpson, A. J. G.; Schryer, M. D.; Cesari, I. M.
Parasitology, Vol. 83, Issue 1
https://doi.org/10.1017/S0031182000050137

Wire interconnects for fabricating interconnected photovoltaic cells
patent, August 2005

Eckert, Robert D.; Gaudiana, Russell; Li, Lian
US Patent Document 6,924,427
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6924427

Asymmetric synthesis of methyl bacteriopheophorbide-d and analogues by stereoselective reduction of the 3-acetyl to the 3-(1-hydroxyethyl) group
journal, June 1998

Tamiaki, Hitoshi; Kouraba, Mitsuru; Takeda, Kenji
Tetrahedron: Asymmetry, Vol. 9, Issue 12
https://doi.org/10.1016/S0957-4166(98)00199-2

Polyethylene glycol modified interferon therapy
patent, February 2003

Glue, Paul William; Cutler, David L.; Affrime, Melton B.
US Patent Document 6,524,570
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6524570

Long-Distance Electron Transfer Across Molecule−Nanocrystalline Semiconductor Interfaces
journal, April 2001

Galoppini, Elena; Guo, Wenzhuo; Qu, Ping
Journal of the American Chemical Society, Vol. 123, Issue 18
https://doi.org/10.1021/ja005932h

Enantioselective Friedel–Crafts Alkylation of Pyrrole with Chalcones Catalyzed by a Dinuclear Zinc Catalyst
journal, November 2014

Hua, Yuan-Zhao; Han, Xing-Wang; Yang, Xiao-Chao
The Journal of Organic Chemistry, Vol. 79, Issue 23
https://doi.org/10.1021/jo5023712

Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite
journal, January 1980

Yoshida, N.; Nussenzweig, R.; Potocnjak, P.
Science, Vol. 207, Issue 4426
https://doi.org/10.1126/science.6985745

Transparent regenerating photoelectrochemical cell
patent, August 1995

Gratzel, Michael; Saurer, Eric
US Patent Document 5,441,827
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5441827

Reaktionen von Pyrrolen mit α,β-ungesättigten Aldehyden und Ketonen
journal, June 1981

Treibs, Alfred; Wilhelm, Roland; Herrmann, Erwin
Liebigs Annalen der Chemie, Vol. 1981, Issue 5
https://doi.org/10.1002/jlac.198119810510

Method for targeted and controlled release of drugs in the intestinal tract and more particularly in the colon
patent, May 1999

Calanchi, Massimo; Zema, Marco; Brunetti, Gabriele
US Patent Document 5,900,252
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5900252

Transdermal patch incorporating a polymer film incorporated with an active agent
patent, January 2000

Wick, John J.; Weimann, Ludwig; Pollock, Wayne C.
US Patent Document 6,010,715
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6010715

Method for producing a CSAp tryptic peptide and anti-CSAp antibodies
patent, August 1984

Goldenberg, Milton D.; Shochat, Dan
US Patent Document 4,468,457
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4468457

Bismuth Trichloride–Catalyzed C‐Alkylation of Pyrroles with Electron‐Deficient Olefins
journal, June 2006

Zhan, Zhuang‐Ping; Yu, Jing‐Liang; Yang, Wen‐Zhen
Synthetic Communications, Vol. 36, Issue 10
https://doi.org/10.1080/00397910500522074

Route to formyl-porphyrins
patent, March 2009

Balakumar, Arumugham; Muthukumaran, Kannan; Lindsey, Jonathan S.
US Patent Document 7,501,507
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7501507

Enantioselective Friedel−Crafts Reaction of β-Trifluoromethylated Acrylates with Pyrroles and Its Application to the Synthesis of Trifluorinated Heliotridane
journal, February 2010

Huang, Yiyong; Tokunaga, Etsuko; Suzuki, Satoru
Organic Letters, Vol. 12, Issue 5
https://doi.org/10.1021/ol100171z

Carbonate diester solutions of PGE-type compounds
patent, October 1983

Yu, Cheng-Der Tony; Bruenner, Ursula
US Patent Document 4,410,545
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4410545

Addition of Heterocycles to Conjugate Unsaturated Carbonyl Compounds: Difunctional Derivatives
journal, February 1951

Webb, I. D.; Borcherdt, G. T.
Journal of the American Chemical Society, Vol. 73, Issue 2
https://doi.org/10.1021/ja01146a074

Synthesis of Phosphono-substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces
patent-application, May 2005

Lindsey, Jonathan S.; Loewe, Robert S.; Muthukumaran, Kannan
US Patent Application 10/698255; 20050096465
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20050096465

Macromolecular environment control in specific receptor assays
patent, February 1983

Litman, David J.; Harel, Zvi; Ullman, Edwin F.
US Patent Document 4,374,925
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4374925

Formation of the isocyclic ring in chlorophyll
journal, February 1969

Cox, Michael T.; Howarth, T. T.; Jackson, Anthony H.
Journal of the American Chemical Society, Vol. 91, Issue 5
https://doi.org/10.1021/ja01033a043

New alternating conductive heteropolymers
journal, April 1991

Kowalik, Janusz; Nguyen, Hiephoa T.; Tolbert, Laren M.
Synthetic Metals, Vol. 41, Issue 1-2
https://doi.org/10.1016/0379-6779(91)91101-F

Targeted gas and gaseous precursor-filled liposomes
patent, June 2000

Unger, Evan C.; Fritz, Thomas; Matsunaga, Terry
US Patent Document 6,071,495
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6071495

Hybrid polypeptides with enhanced pharmacokinetic properties
patent, December 2003

Barney, Shawn O'Lin; Guthrie, Kelly I.; Merutka, Gene
US Patent Document 6,656,906
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6656906

Northern–Southern Route to Synthetic Bacteriochlorins
journal, November 2016

Liu, Yizhou; Lindsey, Jonathan S.
The Journal of Organic Chemistry, Vol. 81, Issue 23
https://doi.org/10.1021/acs.joc.6b02334

Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
patent, June 1985

Eppstein, Deborah A.; Fraser-Smith, Elizabeth; Matthews, Thomas R.
US Patent Document 4,522,811
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4522811

De novo synthesis of bacteriochlorins
patent, March 2014

Kim, Han-Je; Lindsey, Jonathan S.
US Patent Document 8,664,260
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8664260

The total synthesis of chlorophyll
journal, January 1961

Woodward, R. B.
Pure and Applied Chemistry, Vol. 2, Issue 3-4
https://doi.org/10.1351/pac196102030383

Paramagnetic agents for contrast-enhanced NMR imaging: a review
journal, December 1983

Runge, Vm; Clanton, Ja; Lukehart, Cm
American Journal of Roentgenology, Vol. 141, Issue 6
https://doi.org/10.2214/ajr.141.6.1209

Hafnium Chloride Catalyzed Conjugate Addition of Pyrrole, Pyrazole and Imidazole to α,β-Unsaturated Ketones
journal, January 2007

Uenishi, Jun'ichi; Aburatani, Sachiko; Kawatsura, Motoi
HETEROCYCLES, Vol. 71, Issue 1
https://doi.org/10.3987/COM-06-10935

Phyllobilins – the abundant bilin-type tetrapyrrolic catabolites of the green plant pigment chlorophyll
journal, January 2014

Kräutler, Bernhard
Chem. Soc. Rev., Vol. 43, Issue 17
https://doi.org/10.1039/C4CS00079J

Photophysical Properties and Electronic Structure of Stable, Tunable Synthetic Bacteriochlorins: Extending the Features of Native Photosynthetic Pigments
journal, September 2011

Yang, Eunkyung; Kirmaier, Christine; Krayer, Michael
The Journal of Physical Chemistry B, Vol. 115, Issue 37
https://doi.org/10.1021/jp205258s

Probing native-like orientation of pigments in modified reaction centers from Rhodobacter sphaeroides R26 by linear dichroism
journal, September 1996

Meyer, Michaela; Scheer, Hugo; Breton, Jacques
FEBS Letters, Vol. 393, Issue 1
https://doi.org/10.1016/0014-5793(96)00869-1

Substrates carrying polymers of linked sandwich coordination compounds and methods of use thereof
patent, September 2002

Li, Junzhong; Gryko, Dorota; Lindsey, Jonathan S.
US Patent Document 6,451,942
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6451942

Synthesis and photophysical characteristics of 2,3,12,13-tetraalkylbacteriochlorins
journal, January 2016

Zhang, Shaofei; Kim, Han-Je; Tang, Qun
New Journal of Chemistry, Vol. 40, Issue 7
https://doi.org/10.1039/C6NJ00517A

Breakdown of Chlorophyll in Higher Plants-Phyllobilins as Abundant, Yet Hardly Visible Signs of Ripening, Senescence, and Cell Death
journal, February 2016

Kräutler, Bernhard
Angewandte Chemie International Edition, Vol. 55, Issue 16
https://doi.org/10.1002/anie.201508928

Spectroscopy and Structure Determination
book, January 2007

Kobayashi, Masami; Akiyama, Machiko; Kano, Hiromi
Advances in Photosynthesis and Respiration
https://doi.org/10.1007/1-4020-4516-6_6

Gel electrolytes for dye sensitized solar cells
patent, May 2005

Chittibabu, Kethinni; Hadjikyriacou, Savvas
US Patent Document 6,900,382
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6900382

An Overview of Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications
book, January 2007

Scheer, Hugo
Advances in Photosynthesis and Respiration
https://doi.org/10.1007/1-4020-4516-6_1

Method and apparatus for flow cytometry
patent, June 2001

Malachowski, George C.
US Patent Document 6,248,590
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6248590

Characterization of Porphyrins, Chlorins, and Bacteriochlorins Formed via Allomerization of Bacteriochlorophyll a . Synthesis of Highly Stable Bacteriopurpurinimides and Their Metal Complexes
journal, March 2006

Kozyrev, Andrei N.; Chen, Yihui; Goswami, Lalit N.
The Journal of Organic Chemistry, Vol. 71, Issue 5
https://doi.org/10.1021/jo052334i

An Efficient Convergent Synthesis of Novel Anisotropic Adsorbates Based on Nanometer-Sized and Tripod-Shaped Oligophenylenes End-Capped with Triallylsilyl Groups
journal, June 2002

Deng, Xiaobin; Mayeux, Aurelie; Cai, Chengzhi
The Journal of Organic Chemistry, Vol. 67, Issue 15
https://doi.org/10.1021/jo0257750

Fluorescence and Redox Activity of Probes Anchored through an Aminotrithiol to Polycrystalline Gold
journal, February 1998

Fox, Marye Anne; Whitesell, James K.; McKerrow, Andrew J.
Langmuir, Vol. 14, Issue 4
https://doi.org/10.1021/la9707787

Expanded Scope of Synthetic Bacteriochlorins via Improved Acid Catalysis Conditions and Diverse Dihydrodipyrrin-Acetals
journal, February 2010

Krayer, Michael; Ptaszek, Marcin; Kim, Han-Je
The Journal of Organic Chemistry, Vol. 75, Issue 4, p. 1016-1039
https://doi.org/10.1021/jo9025572

The First Examples of Nazarov Cyclizations Leading to Annulated Pyrroles
journal, December 2005

Song, Chuanjun; Knight, David W.; Whatton, Maria A.
Organic Letters, Vol. 8, Issue 1
https://doi.org/10.1021/ol052683z

Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
patent, December 2000

Flower, Ronald J.; Devine, James Michael
US Patent Document 6,167,301
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6167301

Heteroantibody duplexes target cells for lysis by cytotoxic T lymphocytes.
journal, December 1985

Liu, M. A.; Kranz, D. M.; Kurnick, J. T.
Proceedings of the National Academy of Sciences, Vol. 82, Issue 24
https://doi.org/10.1073/pnas.82.24.8648

Solar cells incorporating light harvesting arrays
patent, June 2002

Lindsey, Jonathan S.; Meyer, Gerald
US Patent Document 6,407,330
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6407330

NMR Imaging in Medicine
journal, May 1982

Pykett, Ian L.
Scientific American, Vol. 246, Issue 5
https://doi.org/10.1038/scientificamerican0582-78

Dermatological patch and process for producing thereof
patent, July 2001

Fujii, Kimihiro; Tanaka, Kazuo; Ikawa, Kazuya
US Patent Document 6,267,983
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6267983

Asymmetric Organocatalytic Michael Addition of Pyrroles to Enones by Cinchona Alkaloid-Derived Primary Amines
journal, August 2013

Hack, Daniel; Enders, Dieter
Synthesis, Vol. 45, Issue 20
https://doi.org/10.1055/s-0033-1339546

Micronized aerosol steroids
patent, November 1983

Cook, Peter B.; Hunt, John H.
US Patent Document 4,414,209
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4414209

Alkyl ether analogs of chlorins having an N-substituted imide ring
patent, September 1999

Pandey, Ravindra K.; Potter, William R.; Dougherty, Thomas J.
US Patent Document 5,952,366
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5952366

Chlorophylls, Symmetry, Chirality, and Photosynthesis
journal, September 2014

Senge, Mathias; Ryan, Aoife; Letchford, Kristie
Symmetry, Vol. 6, Issue 3
https://doi.org/10.3390/sym6030781

Ferrocenyl Derivatives with One, Two, or Three Sulfur-Containing Arms for Self-Assembled Monolayer Formation
journal, March 2000

Hu, Jian; Mattern, Daniell Lewis
The Journal of Organic Chemistry, Vol. 65, Issue 8
https://doi.org/10.1021/jo9909812

Steroidal aerosol compositions and process for the preparation thereof
patent, August 1977

Cook, Peter B.; Hunt, John H.
US Patent Document 4,044,126
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4044126

High density non-volatile memory device
patent, December 2003

Bocian, David F.; Kuhr, Werner G.; Lindsey, Jonathan S.
US Patent Document 6,657,884
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6657884

Transdermal patch
patent, September 1999

Burton, Scott A.; Tata, Shahnaz
US Patent Document 5,948,433
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5948433

Partial synthesis of chlorophyll-a from rhodochlorin
journal, January 1981

Smith, Kevin M.; Lewis, W. Michael
Tetrahedron, Vol. 37
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Title: Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds

Abstract

Citation Formats

Dialkylated glycol compositions and medicament preparations containing same patent, May 1976

Tris(3-mercaptopropyl)- N -glycylaminomethane as a New Linker to Bridge Antibody with Metal Particles for Biological Cell Separations journal, June 2000

Photovoltaic cell interconnection patent, March 2004

Catalytic Enantioselective Pyrrole Alkylations of α,β-Unsaturated 2-Acyl Imidazoles journal, May 2006

Epimerization of Chlorophyll Derivatives. V. Effects of the Central Magnesium and Ring Substituents on the Epimerization of Chlorophyll Derivatives journal, November 1992

Photovoltaic fibers patent, July 2005

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Novel bicycloannulation via tandem vinylation and intramolecular Diels-Alder reaction of five-membered heterocycles: a new approach to construction of psoralen and azapsoralen journal, October 1984

Syntheses, characterization, and structural chemistry of biladien-ac-10-one and -bc-5-one metal complexes with 4N or (3N + O) co-ordination journal, January 1996

Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same patent, October 1997

Preparation of bispecific antibodies by chemical recombination of monoclonal immunoglobulin G1 fragments journal, July 1985

High density non-volatile memory device patent, April 2002

Long-Range Electron Transfer across Molecule−Nanocrystalline Semiconductor Interfaces Using Tripodal Sensitizers journal, July 2002

The facile and efficient Michael addition of indoles and pyrrole to α,β-unsaturated electron-deficient compounds catalyzed by aluminium dodecyl sulfate trihydrate [Al(DS) 3 ]·3H 2 O in water journal, January 2005

Method of transdermally administering high molecular weight drugs with a polymer skin enhancer patent, February 2000

Synthesis of tripodal [2]rotaxanes: high concentration principleElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b2/b209836a/ journal, December 2002

Photovoltaic cell patent, August 2005

Swallowtail motifs for imparting water solubility to porphyrinic compounds patent, September 2013

CEA-family antigens, Anti-CEA antibodies and CEA immunoassay patent, April 1989

Packaged pharmaceutical product patent, October 1991

Conjugate addition of pyrroles to α,β-unsaturated ketones using copper bromide as a catalyst journal, October 2006

Method of packaging and sterilizing a pharmaceutical product patent, July 1991

Pulseless liquid supply system for flow cytometry patent, June 1999

The Pigment Complement of the Photosynthetic Reaction Center Isolated from Rhodospirillum rubrum journal, October 1974

Highly Enantioselective Synthesis of β-Heteroaryl-Substituted Dihydrochalcones Through Friedel-Crafts Alkylation of Indoles and Pyrrole journal, February 2010

Selective Michael addition of pyrrole to conjugated alkenes catalyzed by Cr3+-Catsan and ZnCl2 journal, August 2006

Cyclodextrin polymers for carrying and releasing drugs patent, April 2000

Tumor localization and therapy with labeled anti-CEA antibody patent, September 1982

Method for diagnostically imaging lesions in the brain inside a blood-brain barrier patent, October 1991

Taste-masked microcapsule compositions and methods of manufacture patent, October 2000

Method and apparatus for flow cytometry patent, July 2003

Localization of tumors by radiolabelled antibodies patent, December 1975

Microwave-Assisted Addition of Pyrroles to Electron-Deficient Olefins: A Rapid Entry to C -Alkyl Pyrroles journal, January 2005

Pyrroles and related compounds. Part XXX. Cyclisation of porphyrin β-keto-esters to phaeoporphyrins journal, January 1974

Monoclonal antibodies against microorganisms journal, October 1984

De Novo Synthesis of Bacteriochlorins patent-application, August 2006

The Nazarov Cyclization: A Valuable Method to Synthesize Fully Substituted Carbon Stereocenters: Nazarov Cyclization journal, September 2014

Non-immunogenic polypeptides patent, December 1979

Chlorophyll breakdown in higher plants journal, August 2011

The Combination Treatment of Ultrasound and Antitumor Drugs on Yoshida Sarcoma [吉田肉腫に対する抗腫瘍薬と超音波の併用治療] journal, January 1987

Drug mitochondrial targeting agents patent, November 2001

Temperature controlling device for aerosol drug delivery patent, October 2000

Synthesis and Structure of Tolyporphin A O,O -Diacetate journal, October 1999

A General Method for the Catalytic Nazarov Cyclization of Heteroaromatic Compounds journal, October 2006

Acetal stabilized prostaglandin compositions patent, November 1982

Structural characteristics that make chlorophylls green: interplay of hydrocarbon skeleton and substituents journal, January 2011

Pyrroles and related compounds. Part XXVIII. β-Keto-esters in the porphyrin series journal, January 1974

Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier. journal, June 1990

Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery patent, May 2000

Michael Reactions of α-Unsubstituted Trisubstituted 1 H -Pyrroles journal, January 1991

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Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles patent, November 1986

Electrophoretic cuff apparatus drug delivery system patent, November 1999

The total synthesis of chlorophyll a journal, January 1990

Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents patent, November 1999

Recombinant monoclonal antibodies patent, October 1984

Serendipitous synthetic entrée to tetradehydro analogues of cobalamins journal, January 2013

Recent advances in sonodynamic approach to cancer therapy journal, November 1996

Facile synthesis of a B,D-tetradehydrocorrin and rearrangement to bacteriochlorins journal, January 2011

Production of target-specific effector cells using hetero-cross-linked aggregates containing anti-target cell and anti-Fc gamma receptor antibodies. journal, December 1984

Targeted polymerized liposomes for improved drug delivery patent, December 1999

One pot direct synthesis of β-ketoesters via carbonylation of aryl halides using cobalt carbonyl journal, June 2014

Charged lipids and uses for the same patent, September 2000

Metal Triflates-Catalyzed Conjugate Addition of Homochiral Pyrroles to α,β-Unsaturated Esters journal, January 2004

De novo synthesis and photophysical characterization of annulated bacteriochlorins. Mimicking and extending the properties of bacteriochlorophylls journal, January 2011

A New Route for Installing the Isocyclic Ring on Chlorins Yielding 13 1 -Oxophorbines journal, September 2006

Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers patent, May 1982

New Strategies in Organic Catalysis: The First Enantioselective Organocatalytic Friedel−Crafts Alkylation journal, May 2001

Transdermal drug patch with attached pocket for controlled heating device patent, July 2001

Preparation of α- and β-substituted alanine derivatives by α-amidoalkylation or Michael addition reactions under heterogeneous catalysis assisted by microwave irradiation journal, June 2001

Gadolinium triflate catalyzed alkylation of pyrroles: efficient synthesis of 3-oxo-2,3-dihydro-1H-pyrrolizine derivatives journal, June 2007

Enzyme Amplification Assay patent, June 1974

Tetrapartate prodrugs patent, April 2004

Nomenclature of tetrapyrroles (Recommendations 1986) journal, January 1987

Fluorinated Photosensitizers Related to Chlorins and Bacteriochlorins for Photodynamic Therapy patent-application, March 2004

De Novo Synthesis of Gem-Dialkyl Chlorophyll Analogues for Probing and Emulating Our Green World journal, June 2015

Directionally Aligned Helical Peptides on Surfaces journal, July 1993

Dialkylated glycol compositions and medicament preparations containing same
patent, May 1976

Tris(3-mercaptopropyl)- N -glycylaminomethane as a New Linker to Bridge Antibody with Metal Particles for Biological Cell Separations
journal, June 2000

Photovoltaic cell interconnection
patent, March 2004

Catalytic Enantioselective Pyrrole Alkylations of α,β-Unsaturated 2-Acyl Imidazoles
journal, May 2006

Epimerization of Chlorophyll Derivatives. V. Effects of the Central Magnesium and Ring Substituents on the Epimerization of Chlorophyll Derivatives
journal, November 1992

Photovoltaic fibers
patent, July 2005

High-density non-volatile memory devices incorporating sandwich coordination compounds
patent, April 2001

Novel bicycloannulation via tandem vinylation and intramolecular Diels-Alder reaction of five-membered heterocycles: a new approach to construction of psoralen and azapsoralen
journal, October 1984

Syntheses, characterization, and structural chemistry of biladien-ac-10-one and -bc-5-one metal complexes with 4N or (3N + O) co-ordination
journal, January 1996

Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
patent, October 1997

Preparation of bispecific antibodies by chemical recombination of monoclonal immunoglobulin G1 fragments
journal, July 1985

High density non-volatile memory device
patent, April 2002

Long-Range Electron Transfer across Molecule−Nanocrystalline Semiconductor Interfaces Using Tripodal Sensitizers
journal, July 2002

The facile and efficient Michael addition of indoles and pyrrole to α,β-unsaturated electron-deficient compounds catalyzed by aluminium dodecyl sulfate trihydrate [Al(DS) ₃ ]·3H ₂ O in water
journal, January 2005

Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
patent, February 2000

Synthesis of tripodal [2]rotaxanes: high concentration principleElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b2/b209836a/
journal, December 2002

Photovoltaic cell
patent, August 2005

Swallowtail motifs for imparting water solubility to porphyrinic compounds
patent, September 2013

CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
patent, April 1989

Packaged pharmaceutical product
patent, October 1991

Conjugate addition of pyrroles to α,β-unsaturated ketones using copper bromide as a catalyst
journal, October 2006

Method of packaging and sterilizing a pharmaceutical product
patent, July 1991

Pulseless liquid supply system for flow cytometry
patent, June 1999

The Pigment Complement of the Photosynthetic Reaction Center Isolated from Rhodospirillum rubrum
journal, October 1974

Highly Enantioselective Synthesis of β-Heteroaryl-Substituted Dihydrochalcones Through Friedel-Crafts Alkylation of Indoles and Pyrrole
journal, February 2010

Selective Michael addition of pyrrole to conjugated alkenes catalyzed by Cr3+-Catsan and ZnCl2
journal, August 2006

Cyclodextrin polymers for carrying and releasing drugs
patent, April 2000

Tumor localization and therapy with labeled anti-CEA antibody
patent, September 1982

Method for diagnostically imaging lesions in the brain inside a blood-brain barrier
patent, October 1991

Taste-masked microcapsule compositions and methods of manufacture
patent, October 2000

Method and apparatus for flow cytometry
patent, July 2003

Localization of tumors by radiolabelled antibodies
patent, December 1975

Microwave-Assisted Addition of Pyrroles to Electron-Deficient Olefins: A Rapid Entry to C -Alkyl Pyrroles
journal, January 2005

Pyrroles and related compounds. Part XXX. Cyclisation of porphyrin β-keto-esters to phaeoporphyrins
journal, January 1974

Monoclonal antibodies against microorganisms
journal, October 1984

De Novo Synthesis of Bacteriochlorins
patent-application, August 2006

The Nazarov Cyclization: A Valuable Method to Synthesize Fully Substituted Carbon Stereocenters: Nazarov Cyclization
journal, September 2014

Non-immunogenic polypeptides
patent, December 1979

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journal, August 2011

The Combination Treatment of Ultrasound and Antitumor Drugs on Yoshida Sarcoma [吉田肉腫に対する抗腫瘍薬と超音波の併用治療]
journal, January 1987

Drug mitochondrial targeting agents
patent, November 2001

Temperature controlling device for aerosol drug delivery
patent, October 2000

Synthesis and Structure of Tolyporphin A O,O -Diacetate
journal, October 1999

A General Method for the Catalytic Nazarov Cyclization of Heteroaromatic Compounds
journal, October 2006

Acetal stabilized prostaglandin compositions
patent, November 1982

Structural characteristics that make chlorophylls green: interplay of hydrocarbon skeleton and substituents
journal, January 2011

Pyrroles and related compounds. Part XXVIII. β-Keto-esters in the porphyrin series
journal, January 1974

Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier.
journal, June 1990

Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
patent, May 2000

Michael Reactions of α-Unsubstituted Trisubstituted 1 H -Pyrroles
journal, January 1991

Single polypeptide chain binding molecules
patent, August 1990

Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles
patent, November 1986

Electrophoretic cuff apparatus drug delivery system
patent, November 1999

The total synthesis of chlorophyll a
journal, January 1990

Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
patent, November 1999

Recombinant monoclonal antibodies
patent, October 1984

Serendipitous synthetic entrée to tetradehydro analogues of cobalamins
journal, January 2013

Recent advances in sonodynamic approach to cancer therapy
journal, November 1996

Facile synthesis of a B,D-tetradehydrocorrin and rearrangement to bacteriochlorins
journal, January 2011

Production of target-specific effector cells using hetero-cross-linked aggregates containing anti-target cell and anti-Fc gamma receptor antibodies.
journal, December 1984

Targeted polymerized liposomes for improved drug delivery
patent, December 1999

One pot direct synthesis of β-ketoesters via carbonylation of aryl halides using cobalt carbonyl
journal, June 2014

Charged lipids and uses for the same
patent, September 2000

Metal Triflates-Catalyzed Conjugate Addition of Homochiral Pyrroles to α,β-Unsaturated Esters
journal, January 2004

De novo synthesis and photophysical characterization of annulated bacteriochlorins. Mimicking and extending the properties of bacteriochlorophylls
journal, January 2011

A New Route for Installing the Isocyclic Ring on Chlorins Yielding 13 ¹ -Oxophorbines
journal, September 2006

Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
patent, May 1982

New Strategies in Organic Catalysis: The First Enantioselective Organocatalytic Friedel−Crafts Alkylation
journal, May 2001

Transdermal drug patch with attached pocket for controlled heating device
patent, July 2001

Preparation of α- and β-substituted alanine derivatives by α-amidoalkylation or Michael addition reactions under heterogeneous catalysis assisted by microwave irradiation
journal, June 2001

Gadolinium triflate catalyzed alkylation of pyrroles: efficient synthesis of 3-oxo-2,3-dihydro-1H-pyrrolizine derivatives
journal, June 2007

Enzyme Amplification Assay
patent, June 1974

Tetrapartate prodrugs
patent, April 2004

Nomenclature of tetrapyrroles (Recommendations 1986)
journal, January 1987

Fluorinated Photosensitizers Related to Chlorins and Bacteriochlorins for Photodynamic Therapy
patent-application, March 2004

De Novo Synthesis of Gem-Dialkyl Chlorophyll Analogues for Probing and Emulating Our Green World
journal, June 2015

Directionally Aligned Helical Peptides on Surfaces
journal, July 1993

The Total Synthesis of Chlorophyll
journal, July 1960

Proton relaxation enhancement of albumin, immunoglobulin g, and fibrinogen labeled with gd-dtpa
journal, January 1990

Flow cytometry for high throughput screening
patent, May 2005