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Title: Microscopy imaging device with advanced imaging properties

Abstract

Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771547
Patent Number(s):
10813552
Application Number:
15/444,049
Assignee:
The Board of Trustees of the Leland Stanford Junior University (Stanford, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G06 - COMPUTING G06T - IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 02/27/2017
Country of Publication:
United States
Language:
English

Citation Formats

Ghosh, Kunal, Burns, Laurie D., El Gamal, Abbas, Schnitzer, Mark J., Cocker, Eric, and Ho, Tatt Wei. Microscopy imaging device with advanced imaging properties. United States: N. p., 2020. Web.
Ghosh, Kunal, Burns, Laurie D., El Gamal, Abbas, Schnitzer, Mark J., Cocker, Eric, & Ho, Tatt Wei. Microscopy imaging device with advanced imaging properties. United States.
Ghosh, Kunal, Burns, Laurie D., El Gamal, Abbas, Schnitzer, Mark J., Cocker, Eric, and Ho, Tatt Wei. Tue . "Microscopy imaging device with advanced imaging properties". United States. https://www.osti.gov/servlets/purl/1771547.
@article{osti_1771547,
title = {Microscopy imaging device with advanced imaging properties},
author = {Ghosh, Kunal and Burns, Laurie D. and El Gamal, Abbas and Schnitzer, Mark J. and Cocker, Eric and Ho, Tatt Wei},
abstractNote = {Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {10}
}

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