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Title: Dynamically-adaptive live therapeutic agents and methods of use thereof

Abstract

This disclosure provides microbes engineered to detect virulent and spore states of pathogens and release an appropriate therapeutic response accordingly and compositions and methods of use of the same.

Inventors:
; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771529
Patent Number(s):
10808232
Application Number:
15/438,638
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 02/21/2017
Country of Publication:
United States
Language:
English

Citation Formats

Yung, Mimi Cho, Coleman, Matthew A., D'Haeseleer, Patrik, Harris, Howard, Jiao, Yongqin, Overton, Kenneth W., Park, Dan Mcfarland, Segelke, Brent W., and Wong, Sergio E. Dynamically-adaptive live therapeutic agents and methods of use thereof. United States: N. p., 2020. Web.
Yung, Mimi Cho, Coleman, Matthew A., D'Haeseleer, Patrik, Harris, Howard, Jiao, Yongqin, Overton, Kenneth W., Park, Dan Mcfarland, Segelke, Brent W., & Wong, Sergio E. Dynamically-adaptive live therapeutic agents and methods of use thereof. United States.
Yung, Mimi Cho, Coleman, Matthew A., D'Haeseleer, Patrik, Harris, Howard, Jiao, Yongqin, Overton, Kenneth W., Park, Dan Mcfarland, Segelke, Brent W., and Wong, Sergio E. Tue . "Dynamically-adaptive live therapeutic agents and methods of use thereof". United States. https://www.osti.gov/servlets/purl/1771529.
@article{osti_1771529,
title = {Dynamically-adaptive live therapeutic agents and methods of use thereof},
author = {Yung, Mimi Cho and Coleman, Matthew A. and D'Haeseleer, Patrik and Harris, Howard and Jiao, Yongqin and Overton, Kenneth W. and Park, Dan Mcfarland and Segelke, Brent W. and Wong, Sergio E.},
abstractNote = {This disclosure provides microbes engineered to detect virulent and spore states of pathogens and release an appropriate therapeutic response accordingly and compositions and methods of use of the same.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {10}
}

Works referenced in this record:

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