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Title: High efficiency continuous-flow production of radioisotopes

Abstract

Methods and systems are provided for continuous-flow production of radioisotopes with high specific activity. Radioisotopes with high specific activity produced according to the methods described are also provided. The methods can include causing a liquid capture matrix to contact a target containing a target nuclide; irradiating the target with radiation, ionizing radiation, particles, or a combination thereof to produce the radionuclides that are ejected from the target and into the capture matrix; and causing the liquid capture matrix containing the radionuclides to flow from the target to recover the capture matrix containing the radionuclides with high specific activity. The methods are suitable for the production of a variety of radionuclides. For example, in some aspects the target nuclide is 237Np, and the radionuclide is 238Np that decays to produce 238Pu. In other aspects, the target nuclide is 98Mo, and the radionuclide is Mo that decays to produce 99mTc.

Inventors:
; ;
Issue Date:
Research Org.:
Univ. of California, Irvine, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771508
Patent Number(s):
10804000
Application Number:
15/598,918
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07F - ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
DOE Contract Number:  
NE0000361
Resource Type:
Patent
Resource Relation:
Patent File Date: 05/18/2017
Country of Publication:
United States
Language:
English

Citation Formats

Nilsson, Mikael, Safavi-Tehrani, Leila, and Miller, George E. High efficiency continuous-flow production of radioisotopes. United States: N. p., 2020. Web.
Nilsson, Mikael, Safavi-Tehrani, Leila, & Miller, George E. High efficiency continuous-flow production of radioisotopes. United States.
Nilsson, Mikael, Safavi-Tehrani, Leila, and Miller, George E. Tue . "High efficiency continuous-flow production of radioisotopes". United States. https://www.osti.gov/servlets/purl/1771508.
@article{osti_1771508,
title = {High efficiency continuous-flow production of radioisotopes},
author = {Nilsson, Mikael and Safavi-Tehrani, Leila and Miller, George E.},
abstractNote = {Methods and systems are provided for continuous-flow production of radioisotopes with high specific activity. Radioisotopes with high specific activity produced according to the methods described are also provided. The methods can include causing a liquid capture matrix to contact a target containing a target nuclide; irradiating the target with radiation, ionizing radiation, particles, or a combination thereof to produce the radionuclides that are ejected from the target and into the capture matrix; and causing the liquid capture matrix containing the radionuclides to flow from the target to recover the capture matrix containing the radionuclides with high specific activity. The methods are suitable for the production of a variety of radionuclides. For example, in some aspects the target nuclide is 237Np, and the radionuclide is 238Np that decays to produce 238Pu. In other aspects, the target nuclide is 98Mo, and the radionuclide is Mo that decays to produce 99mTc.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {10}
}

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