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Title: Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway

Abstract

The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as sugars, alcohols, chemicals, amino acids, polymers, fatty acids and their derivatives, hydrocarbons, isoprenoids, and intermediates thereof, in organisms such that these organisms efficiently convert inorganic carbon to organic carbon-based products of interest using inorganic energy, such as formate, and in particular the use of organisms for the commercial production of various carbon-based products of interest.

Inventors:
; ; ;
Issue Date:
Research Org.:
Gingko Bioworks, Inc., Boston, MA (United States)
Sponsoring Org.:
USDOE Advanced Research Projects Agency - Energy (ARPA-E)
OSTI Identifier:
1771496
Patent Number(s):
10801045
Application Number:
15/867,209
Assignee:
Ginkgo Bioworks, Inc. (Boston, MA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AR0000091
Resource Type:
Patent
Resource Relation:
Patent File Date: 01/10/2018
Country of Publication:
United States
Language:
English

Citation Formats

Fischer, Curt R., Che, Austin J., Shetty, Reshma P., and Kelly, Jason R. Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway. United States: N. p., 2020. Web.
Fischer, Curt R., Che, Austin J., Shetty, Reshma P., & Kelly, Jason R. Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway. United States.
Fischer, Curt R., Che, Austin J., Shetty, Reshma P., and Kelly, Jason R. Tue . "Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway". United States. https://www.osti.gov/servlets/purl/1771496.
@article{osti_1771496,
title = {Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway},
author = {Fischer, Curt R. and Che, Austin J. and Shetty, Reshma P. and Kelly, Jason R.},
abstractNote = {The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as sugars, alcohols, chemicals, amino acids, polymers, fatty acids and their derivatives, hydrocarbons, isoprenoids, and intermediates thereof, in organisms such that these organisms efficiently convert inorganic carbon to organic carbon-based products of interest using inorganic energy, such as formate, and in particular the use of organisms for the commercial production of various carbon-based products of interest.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {10}
}

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